Haplotyping germline and cancer genomes with high-throughput linked-read sequencing GXY Zheng, BT Lau, M Schnall-Levin, M Jarosz, JM Bell, CM Hindson, ... Nature biotechnology 34 (3), 303-311, 2016 | 830 | 2016 |
High Sensitivity Detection and Quantitation of DNA Copy Number and Single Nucleotide Variants with Single Color Droplet Digital PCR LK Miotke, BT Lau, RT Rumma, HP Ji Analytical Chemistry, 2014 | 254 | 2014 |
Single-cell genomic characterization reveals the cellular reprogramming of the gastric tumor microenvironment A Sathe, SM Grimes, BT Lau, J Chen, C Suarez, RJ Huang, G Poultsides, ... Clinical Cancer Research 26 (11), 2640-2653, 2020 | 253 | 2020 |
A complete microfluidic screening platform for rational protein crystallization BTC Lau, CA Baitz, XP Dong, CL Hansen Journal of the American Chemical Society 129 (3), 454-455, 2007 | 164 | 2007 |
Improved read/write cost tradeoff in DNA-based data storage using LDPC codes S Chandak, K Tatwawadi, B Lau, J Mardia, M Kubit, J Neu, P Griffin, ... 2019 57th Annual Allerton Conference on Communication, Control, and …, 2019 | 79 | 2019 |
Joint single cell DNA-seq and RNA-seq of gastric cancer cell lines reveals rules of in vitro evolution N Andor, BT Lau, C Catalanotti, A Sathe, M Kubit, J Chen, C Blaj, ... NAR Genomics and Bioinformatics 2 (2), lqaa016, 2020 | 75 | 2020 |
New quantitative methods for measuring plasmid loss rates reveal unexpected stability BTC Lau, P Malkus, J Paulsson Plasmid 70 (3), 353-361, 2013 | 73 | 2013 |
Linked read sequencing resolves complex genomic rearrangements in gastric cancer metastases SU Greer, LD Nadauld, BT Lau, J Chen, C Wood-Bouwens, JM Ford, ... Genome medicine 9 (1), 1-17, 2017 | 70 | 2017 |
Overcoming high nanopore basecaller error rates for DNA storage via basecaller-decoder integration and convolutional codes S Chandak, J Neu, K Tatwawadi, J Mardia, B Lau, M Kubit, R Hulett, ... ICASSP 2020-2020 IEEE International Conference on Acoustics, Speech and …, 2020 | 58 | 2020 |
CRISPR–Cas9-targeted fragmentation and selective sequencing enable massively parallel microsatellite analysis GW Shin, SM Grimes, HJ Lee, BT Lau, LC Xia, HP Ji Nature communications 8 (1), 1-13, 2017 | 55 | 2017 |
Integrative single-cell analysis of allele-specific copy number alterations and chromatin accessibility in cancer CY Wu, BT Lau, HS Kim, A Sathe, SM Grimes, HP Ji, NR Zhang Nature Biotechnology 39 (10), 1259-1269, 2021 | 46 | 2021 |
Colorectal cancer metastases in the liver establish immunosuppressive spatial networking between tumor associated SPP1+ macrophages and fibroblasts. A Sathe, K Mason, SM Grimes, Z Zhou, BT Lau, X Bai, A Su, X Tan, H Lee, ... Clinical Cancer Research: an Official Journal of the American Association …, 2022 | 45 | 2022 |
Single-cell transcriptome analysis identifies distinct cell types and niche signaling in a primary gastric organoid model J Chen, BT Lau, N Andor, SM Grimes, C Handy, C Wood-Bouwens, HP Ji Scientific reports 9 (1), 1-12, 2019 | 37 | 2019 |
Profiling SARS-CoV-2 mutation fingerprints that range from the viral pangenome to individual infection quasispecies BT Lau, D Pavlichin, AC Hooker, A Almeda, G Shin, J Chen, MK Sahoo, ... Genome Medicine 13 (1), 1-23, 2021 | 29 | 2021 |
Chromosome-scale mega-haplotypes enable digital karyotyping of cancer aneuploidy JM Bell, BT Lau, SU Greer, C Wood-Bouwens, LC Xia, ID Connolly, ... Nucleic acids research, 2017 | 29 | 2017 |
A functional CRISPR/Cas9 screen identifies kinases that modulate FGFR inhibitor response in gastric cancer J Chen, J Bell, BT Lau, T Whittaker, D Stapleton, HP Ji Oncogenesis 8 (5), 33, 2019 | 24 | 2019 |
Robust Multiplexed Clustering and Denoising of Digital PCR Assays by Data Gridding BT Lau, C Wood-Bouwens, HP Ji Analytical chemistry 89 (22), 11913-11917, 2017 | 21 | 2017 |
Joint single cell DNA-Seq and RNA-Seq of gastric cancer reveals subclonal signatures of genomic instability and gene expression N Andor, BT Lau, C Catalanotti, V Kumar, A Sathe, K Belhocine, ... bioRxiv, 445932, 2018 | 19 | 2018 |
Single-Color Digital PCR Provides High-Performance Detection of Cancer Mutations from Circulating DNA C Wood-Bouwens, BT Lau, CM Handy, HJ Lee, HP Ji The Journal of Molecular Diagnostics 19 (5), 697-710, 2017 | 18 | 2017 |
Single-cell characterization of CRISPR-modified transcript isoforms with nanopore sequencing HS Kim, SM Grimes, AC Hooker, BT Lau, HP Ji Genome biology 22 (1), 1-16, 2021 | 15 | 2021 |