Mechanistic understanding of lanthipeptide biosynthetic enzymes LM Repka, JR Chekan, SK Nair, WA Van Der Donk Chemical reviews 117 (8), 5457-5520, 2017 | 457 | 2017 |
Xylan utilization in human gut commensal bacteria is orchestrated by unique modular organization of polysaccharide-degrading enzymes M Zhang, JR Chekan, D Dodd, PY Hong, L Radlinski, V Revindran, ... Proceedings of the National Academy of Sciences 111 (35), E3708-E3717, 2014 | 177 | 2014 |
Biosynthesis of the neurotoxin domoic acid in a bloom-forming diatom JK Brunson, SMK McKinnie, JR Chekan, JP McCrow, ZD Miles, ... Science 361 (6409), 1356-1358, 2018 | 153 | 2018 |
Discovery of a new ATP-binding motif involved in peptidic azoline biosynthesis KL Dunbar, JR Chekan, CL Cox, BJ Burkhart, SK Nair, DA Mitchell Nature chemical biology 10 (10), 823-829, 2014 | 100 | 2014 |
Genome mining methods to discover bioactive natural products KD Bauman, KS Butler, BS Moore, JR Chekan Natural Product Reports 38 (11), 2100-2129, 2021 | 87 | 2021 |
Guanitoxin, re-naming a cyanobacterial organophosphate toxin MF Fiore, ST de Lima, WW Carmichael, SMK McKinnie, JR Chekan, ... Harmful Algae 92, 101737, 2020 | 79 | 2020 |
Characterization of the macrocyclase involved in the biosynthesis of RiPP cyclic peptides in plants JR Chekan, P Estrada, PS Covello, SK Nair Proceedings of the National Academy of Sciences 114 (25), 6551-6556, 2017 | 65 | 2017 |
Scalable Biosynthesis of the Seaweed Neurochemical, Kainic Acid JR Chekan, SMK McKinnie, ML Moore, SG Poplawski, TP Michael, ... Angewandte Chemie 131 (25), 8542-8545, 2019 | 59 | 2019 |
Steric complementarity directs sequence promiscuous leader binding in RiPP biosynthesis JR Chekan, C Ongpipattanakul, SK Nair Proceedings of the National Academy of Sciences 116 (48), 24049-24055, 2019 | 43 | 2019 |
Biosynthesis of l‐4‐Chlorokynurenine, an Antidepressant Prodrug and a Non‐Proteinogenic Amino Acid Found in Lipopeptide Antibiotics H Luhavaya, R Sigrist, JR Chekan, SMK McKinnie, BS Moore Angewandte Chemie International Edition 58 (25), 8394-8399, 2019 | 43 | 2019 |
Molecular basis for resistance against phosphonate antibiotics and herbicides JR Chekan, DP Cogan, SK Nair MedChemComm 7 (1), 28-36, 2016 | 37 | 2016 |
Structure of the lasso peptide isopeptidase identifies a topology for processing threaded substrates JR Chekan, JD Koos, C Zong, MO Maksimov, AJ Link, SK Nair Journal of the American Chemical Society 138 (50), 16452-16458, 2016 | 35 | 2016 |
A common late-stage intermediate in catalysis by 2-hydroxyethyl-phosphonate dioxygenase and methylphosphonate synthase SC Peck, JR Chekan, EC Ulrich, SK Nair, WA Van Der Donk Journal of the American Chemical Society 137 (9), 3217-3220, 2015 | 27 | 2015 |
Biosynthesis of guanitoxin enables global environmental detection in freshwater cyanobacteria ST Lima, TR Fallon, JL Cordoza, JR Chekan, E Delbaje, AR Hopiavuori, ... Journal of the American Chemical Society 144 (21), 9372-9379, 2022 | 24 | 2022 |
Biosynthesis of marine toxins JR Chekan, TR Fallon, BS Moore Current Opinion in Chemical Biology 59, 119-129, 2020 | 24 | 2020 |
Structure and function of phosphonoacetaldehyde dehydrogenase: the missing link in phosphonoacetate formation V Agarwal, SC Peck, JH Chen, SA Borisova, JR Chekan, ... Chemistry & biology 21 (1), 125-135, 2014 | 23 | 2014 |
Domoic acid biosynthesis in the red alga Chondria armata suggests a complex evolutionary history for toxin production TS Steele, JK Brunson, Y Maeno, R Terada, AE Allen, M Yotsu-Yamashita, ... Proceedings of the National Academy of Sciences 119 (6), e2117407119, 2022 | 21 | 2022 |
Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants JR Chekan, C Ongpipattanakul, TR Wright, B Zhang, JM Bollinger Jr, ... Proceedings of the National Academy of Sciences 116 (27), 13299-13304, 2019 | 19 | 2019 |
Structural and biochemical basis for mannan utilization by Caldanaerobius polysaccharolyticus strain ATCC BAA-17 JR Chekan, IH Kwon, V Agarwal, D Dodd, V Revindran, RI Mackie, I Cann, ... Journal of Biological Chemistry 289 (50), 34965-34977, 2014 | 19 | 2014 |
Characterization of Two Late-Stage Enzymes Involved in Fosfomycin Biosynthesis in Pseudomonads P Olivares, EC Ulrich, JR Chekan, WA van der Donk, SK Nair ACS Chemical Biology 12 (2), 456–463, 2017 | 18 | 2017 |