Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes A Lu, VG Magupalli, J Ruan, Q Yin, MK Atianand, MR Vos, GF Schröder, ... Cell 156 (6), 1193-1206, 2014 | 1261 | 2014 |
Hydrolysis of 2′ 3′-cGAMP by ENPP1 and design of nonhydrolyzable analogs L Li, Q Yin, P Kuss, Z Maliga, JL Millán, H Wu, TJ Mitchison Nature chemical biology 10 (12), 1043-1048, 2014 | 436 | 2014 |
Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization L Zhang, S Chen, J Ruan, J Wu, AB Tong, Q Yin, Y Li, L David, A Lu, ... Science 350 (6259), 404-409, 2015 | 414 | 2015 |
E2 interaction and dimerization in the crystal structure of TRAF6 Q Yin, SC Lin, B Lamothe, M Lu, YC Lo, G Hura, L Zheng, RL Rich, ... Nature structural & molecular biology 16 (6), 658-666, 2009 | 388 | 2009 |
The Fas–FADD death domain complex structure reveals the basis of DISC assembly and disease mutations L Wang, JK Yang, V Kabaleeswaran, AJ Rice, AC Cruz, AY Park, Q Yin, ... Nature structural & molecular biology 17 (11), 1324-1329, 2010 | 312 | 2010 |
Cyclic di-GMP sensing via the innate immune signaling protein STING Q Yin, Y Tian, V Kabaleeswaran, X Jiang, D Tu, MJ Eck, ZJ Chen, H Wu Molecular cell 46 (6), 735-745, 2012 | 306 | 2012 |
AIM2 inflammasome activation and regulation: a structural perspective B Wang, Q Yin Journal of structural biology 200 (3), 279-282, 2017 | 195 | 2017 |
Structural studies of NF-κB signaling C Zheng, Q Yin, H Wu Cell research 21 (1), 183-195, 2011 | 194 | 2011 |
Anticancer flavonoids are mouse-selective STING agonists S Kim, L Li, Z Maliga, Q Yin, H Wu, TJ Mitchison ACS chemical biology 8 (7), 1396-1401, 2013 | 172 | 2013 |
Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism A Lu, Y Li, FI Schmidt, Q Yin, S Chen, T Fu, AB Tong, HL Ploegh, Y Mao, ... Nature Structural and Molecular Biology 23 (5), 416-425, 2016 | 164 | 2016 |
Dimerization and ubiquitin mediated recruitment of A20, a complex deubiquitinating enzyme TT Lu, M Onizawa, GE Hammer, EE Turer, Q Yin, E Damko, A Agelidis, ... Immunity 38 (5), 896-905, 2013 | 163 | 2013 |
A dimeric Smac/diablo peptide directly relieves caspase-3 inhibition by XIAP Dynamic and cooperative regulation of XIAP by Smac/Diablo Z Gao, Y Tian, J Wang, Q Yin, H Wu, YM Li, X Jiang Journal of Biological Chemistry 282 (42), 30718-30727, 2007 | 160 | 2007 |
Structural basis of signal transduction in the TNF receptor superfamily J Li, Q Yin, H Wu Advances in immunology 119, 135-153, 2013 | 143 | 2013 |
Structural Biology of Innate Immunity Q Yin, TM Fu, J Li, H Wu Annual Review of Immunology 33 (1), 2015 | 123 | 2015 |
Structural basis for the lack of E2 interaction in the RING domain of TRAF2 Q Yin, B Lamothe, BG Darnay, H Wu Biochemistry 48 (44), 10558-10567, 2009 | 118 | 2009 |
Caspase-9 holoenzyme is a specific and optimal procaspase-3 processing machine Q Yin, HH Park, JY Chung, SC Lin, YC Lo, LS da Graca, X Jiang, H Wu Molecular cell 22 (2), 259-268, 2006 | 102 | 2006 |
Molecular mechanism for p202-mediated specific inhibition of AIM2 inflammasome activation Q Yin, DP Sester, Y Tian, YS Hsiao, A Lu, JA Cridland, V Sagulenko, ... Cell reports 4 (2), 327-339, 2013 | 97 | 2013 |
Plasticity in PYD assembly revealed by cryo-EM structure of the PYD filament of AIM2 A Lu, Y Li, Q Yin, J Ruan, X Yu, E Egelman, H Wu Cell discovery 1 (1), 1-14, 2015 | 94 | 2015 |
Molecular basis for the unique specificity of TRAF6 JY Chung, M Lu, Q Yin, SC Lin, H Wu TNF Receptor Associated Factors (TRAFs), 122-130, 2007 | 88 | 2007 |
Multimeric assembly and biochemical characterization of the Trax–translin endonuclease complex Y Tian, DK Simanshu, M Ascano, R Diaz-Avalos, AY Park, SA Juranek, ... Nature structural & molecular biology 18 (6), 658-664, 2011 | 75 | 2011 |