The global problem of antifungal resistance: prevalence, mechanisms, and management DS Perlin, R Rautemaa-Richardson, A Alastruey-Izquierdo The Lancet infectious diseases 17 (12), e383-e392, 2017 | 983 | 2017 |
Frequency and evolution of azole resistance in Aspergillus fumigatus associated with treatment failure SJ Howard, D Cerar, MJ Anderson, A Albarrag, MC Fisher, ... Emerging infectious diseases 15 (7), 1068, 2009 | 879 | 2009 |
Increasing Echinocandin Resistance in Candida glabrata: Clinical Failure Correlates With Presence of FKS Mutations and Elevated Minimum Inhibitory … BD Alexander, MD Johnson, CD Pfeiffer, C Jiménez-Ortigosa, J Catania, ... Clinical infectious diseases 56 (12), 1724-1732, 2013 | 866 | 2013 |
Resistance to echinocandin-class antifungal drugs DS Perlin Drug Resistance Updates 10 (3), 121-130, 2007 | 668 | 2007 |
Mechanisms of antifungal drug resistance LE Cowen, D Sanglard, SJ Howard, PD Rogers, DS Perlin Cold Spring Harbor perspectives in medicine 5 (7), a019752, 2015 | 637 | 2015 |
Specific Substitutions in the Echinocandin Target Fks1p Account for Reduced Susceptibility of Rare Laboratory and Clinical Candida sp. Isolates S Park, R Kelly, JN Kahn, J Robles, MJ Hsu, E Register, W Li, V Vyas, ... Antimicrobial agents and chemotherapy 49 (8), 3264-3273, 2005 | 521 | 2005 |
A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009–17) in India: role of the ERG11 and FKS1 genes in azole and … A Chowdhary, A Prakash, C Sharma, M Kordalewska, A Kumar, S Sarma, ... Journal of Antimicrobial Chemotherapy 73 (4), 891-899, 2018 | 501 | 2018 |
Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens BM Hover, SH Kim, M Katz, Z Charlop-Powers, JG Owen, MA Ternei, ... Nature microbiology 3 (4), 415-422, 2018 | 438 | 2018 |
Clinical breakpoints for the echinocandins and Candida revisited: integration of molecular, clinical, and microbiological data to arrive at species-specific interpretive criteria MA Pfaller, DJ Diekema, D Andes, MC Arendrup, SD Brown, SR Lockhart, ... Drug Resistance Updates 14 (3), 164-176, 2011 | 379 | 2011 |
A Naturally Occurring Proline-to-Alanine Amino Acid Change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis Accounts for … G Garcia-Effron, SK Katiyar, S Park, TD Edlind, DS Perlin Antimicrobial agents and chemotherapy 52 (7), 2305-2312, 2008 | 372 | 2008 |
High-frequency triazole resistance found in nonculturable Aspergillus fumigatus from lungs of patients with chronic fungal disease DW Denning, S Park, C Lass-Florl, MG Fraczek, M Kirwan, R Gore, ... Clinical infectious diseases 52 (9), 1123-1129, 2011 | 367 | 2011 |
Effect of Candida glabrata FKS1 and FKS2 Mutations on Echinocandin Sensitivity and Kinetics of 1,3-β-d-Glucan Synthase: Implication for the Existing … G Garcia-Effron, S Lee, S Park, JD Cleary, DS Perlin Antimicrobial agents and chemotherapy 53 (9), 3690-3699, 2009 | 360 | 2009 |
Echinocandin Resistance in Candida DS Perlin Clinical Infectious Diseases 61 (suppl_6), S612-S617, 2015 | 349 | 2015 |
Echinocandin resistance: an emerging clinical problem? MC Arendrup, DS Perlin Current opinion in infectious diseases 27 (6), 484-492, 2014 | 342 | 2014 |
Current perspectives on echinocandin class drugs DS Perlin Future microbiology 6 (4), 441-457, 2011 | 310 | 2011 |
Multiple Resistance Mechanisms among Aspergillus fumigatus Mutants with High-Level Resistance to Itraconazole AM Nascimento, GH Goldman, S Park, SAE Marras, G Delmas, U Oza, ... Antimicrobial agents and chemotherapy 47 (5), 1719-1726, 2003 | 302 | 2003 |
Correlating Echinocandin MIC and Kinetic Inhibition of fks1 Mutant Glucan Synthases for Candida albicans: Implications for Interpretive Breakpoints G Garcia-Effron, S Park, DS Perlin Antimicrobial agents and chemotherapy 53 (1), 112-122, 2009 | 297 | 2009 |
Mechanisms of echinocandin antifungal drug resistance DS Perlin Annals of the new York Academy of Sciences 1354 (1), 1-11, 2015 | 293 | 2015 |
Assessing Resistance to the Echinocandin Antifungal Drug Caspofungin in Candida albicans by Profiling Mutations in FKS1 SV Balashov, S Park, DS Perlin Antimicrobial agents and chemotherapy 50 (6), 2058-2063, 2006 | 280 | 2006 |
Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance KR Healey, Y Zhao, WB Perez, SR Lockhart, JD Sobel, D Farmakiotis, ... Nature communications 7 (1), 11128, 2016 | 267 | 2016 |