The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells. HHN Jian-Chien Dominic Heng, Bo Feng, Jianyong Han, Jianming Jiang, Petra ... Cell stem cell 6 (2), 167-174, 2010 | 596 | 2010 |
A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity NY Chia, YS Chan, B Feng, X Lu, YL Orlov, D Moreau, P Kumar, L Yang, ... Nature 468 (7321), 316, 2010 | 547 | 2010 |
Long noncoding RNAs: fresh perspectives into the RNA world L Yang, JE Froberg, JT Lee Trends in biochemical sciences 39 (1), 35-43, 2014 | 389 | 2014 |
Transcriptional regulatory networks in embryonic stem cells YS Chan, L Yang, HH Ng Epigenetics and Disease, 239-252, 2011 | 144 | 2011 |
Guided by RNAs: X-inactivation as a model for lncRNA function JE Froberg, L Yang, JT Lee Journal of molecular biology 425 (19), 3698-3706, 2013 | 142 | 2013 |
Loss of H3K27me3 imprinting in somatic cell nuclear transfer embryos disrupts post-implantation development S Matoba, H Wang, L Jiang, F Lu, KA Iwabuchi, X Wu, K Inoue, L Yang, ... Cell stem cell 23 (3), 343-354. e5, 2018 | 136 | 2018 |
Female mice lacking Xist RNA show partial dosage compensation and survive to term L Yang, JE Kirby, H Sunwoo, JT Lee Genes & development 30 (15), 1747-1760, 2016 | 79 | 2016 |
RNAi reveals phase-specific global regulators of human somatic cell reprogramming CXD Toh, JW Chan, ZS Chong, HF Wang, HC Guo, S Satapathy, D Ma, ... Cell reports 15 (12), 2597-2607, 2016 | 56 | 2016 |
Lewy Body–like Inclusions in Human Midbrain Organoids Carrying Glucocerebrosidase and α‐Synuclein Mutations J Jo, L Yang, HD Tran, W Yu, AX Sun, YY Chang, BC Jung, SJ Lee, ... Annals of Neurology 90 (3), 490-505, 2021 | 51 | 2021 |
Genomic approaches to deconstruct pluripotency YH Loh, L Yang, JC Yang, H Li, JJ Collins, GQ Daley Annual review of genomics and human genetics 12, 165-185, 2011 | 47 | 2011 |
Widespread organ tolerance to Xist loss and X reactivation except under chronic stress in the gut L Yang, E Yildirim, JE Kirby, W Press, JT Lee Proceedings of the National Academy of Sciences 117 (8), 4262-4272, 2020 | 40 | 2020 |
Lab-grown mini-brains upgraded L Yang, HH Ng Nature Cell Biology 19 (9), 1010-1012, 2017 | 6 | 2017 |