The allelic landscape of human blood cell trait variation and links to common complex disease WJ Astle, H Elding, T Jiang, D Allen, D Ruklisa, AL Mann, D Mead, ... Cell 167 (5), 1415-1429. e19, 2016 | 1189 | 2016 |
Multiple evidence strands suggest that there may be as few as 19 000 human protein-coding genes I Ezkurdia, D Juan, JM Rodriguez, A Frankish, M Diekhans, J Harrow, ... Human molecular genetics 23 (22), 5866-5878, 2014 | 788 | 2014 |
Emerging methods in protein co-evolution D De Juan, F Pazos, A Valencia Nature Reviews Genetics 14 (4), 249-261, 2013 | 650 | 2013 |
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 627 | 2020 |
Spatiotemporal transcriptomic divergence across human and macaque brain development Y Zhu, AMM Sousa, T Gao, M Skarica, M Li, G Santpere, ... Science 362 (6420), eaat8077, 2018 | 302 | 2018 |
A comparative genomics multitool for scientific discovery and conservation Nature 587 (7833), 240-245, 2020 | 237 | 2020 |
Identification of amino acid residues crucial for chemokine receptor dimerization P Hernanz-Falcon, JM Rodríguez-Frade, A Serrano, D Juan, A Del Sol, ... Nature immunology 5 (2), 216-223, 2004 | 233 | 2004 |
High-confidence prediction of global interactomes based on genome-wide coevolutionary networks D Juan, F Pazos, A Valencia Proceedings of the National Academy of Sciences 105 (3), 934-939, 2008 | 212 | 2008 |
Protein interactions and ligand binding: from protein subfamilies to functional specificity A Rausell, D Juan, F Pazos, A Valencia Proceedings of the National Academy of Sciences 107 (5), 1995-2000, 2010 | 170 | 2010 |
Assessing protein co-evolution in the context of the tree of life assists in the prediction of the interactome F Pazos, JAG Ranea, D Juan, MJE Sternberg Journal of molecular biology 352 (4), 1002-1015, 2005 | 163 | 2005 |
Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types S Ecker, L Chen, V Pancaldi, FO Bagger, JM Fernández, ... Genome biology 18, 1-17, 2017 | 116 | 2017 |
Intronic CNVs and gene expression variation in human populations M Rigau, D Juan, A Valencia, D Rico PLoS Genetics 15 (1), e1007902, 2019 | 87 | 2019 |
Evolutionary constraint and innovation across hundreds of placental mammals MJ Christmas, IM Kaplow, DP Genereux, MX Dong, GM Hughes, X Li, ... Science 380 (6643), eabn3943, 2023 | 83 | 2023 |
Reconstructing Denisovan anatomy using DNA methylation maps D Gokhman, N Mishol, M de Manuel, D de Juan, J Shuqrun, E Meshorer, ... Cell 179 (1), 180-192. e10, 2019 | 76 | 2019 |
Subfunctionalization via adaptive evolution influenced by genomic context: the case of histone chaperones ASF1a and ASF1b F Abascal, A Corpet, ZA Gurard-Levin, D Juan, F Ochsenbein, D Rico, ... Molecular biology and evolution 30 (8), 1853-1866, 2013 | 76 | 2013 |
Loose ends: almost one in five human genes still have unresolved coding status F Abascal, D Juan, I Jungreis, L Martinez, M Rigau, JM Rodriguez, ... Nucleic acids research 46 (14), 7070-7084, 2018 | 69 | 2018 |
Selective single molecule sequencing and assembly of a human Y chromosome of African origin LFK Kuderna, E Lizano, E Julià, J Gomez-Garrido, A Serres-Armero, ... Nature communications 10 (1), 4, 2019 | 64 | 2019 |
Co-evolution and co-adaptation in protein networks D Juan, F Pazos, A Valencia FEBS letters 582 (8), 1225-1230, 2008 | 60 | 2008 |
A global catalog of whole-genome diversity from 233 primate species LFK Kuderna, H Gao, MC Janiak, M Kuhlwilm, JD Orkin, T Bataillon, ... Science 380 (6648), 906-913, 2023 | 58 | 2023 |
Integrating epigenomic data and 3D genomic structure with a new measure of chromatin assortativity V Pancaldi, E Carrillo-de-Santa-Pau, BM Javierre, D Juan, P Fraser, ... Genome biology 17, 1-19, 2016 | 56 | 2016 |