Design, synthesis, molecular modeling and anti-proliferative evaluation of novel quinoxaline derivatives as potential DNA intercalators and topoisomerase II inhibitors MK Ibrahim, MS Taghour, AM Metwaly, A Belal, ABM Mehany, ... European journal of medicinal chemistry 155, 117-134, 2018 | 110 | 2018 |
Discovery of new pyrimidine-5-carbonitrile derivatives as anticancer agents targeting EGFR WT and EGFR T790M AA Nasser, IH Eissa, MR Oun, MA El-Zahabi, MS Taghour, A Belal, ... Organic & biomolecular chemistry 18 (38), 7608-7634, 2020 | 109 | 2020 |
New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies H Elkady, A Elwan, HA El-Mahdy, AS Doghish, A Ismail, MS Taghour, ... Journal of enzyme inhibition and medicinal chemistry 37 (1), 403-416, 2022 | 105 | 2022 |
Design and synthesis of thiazolidine-2, 4-diones hybrids with 1, 2-dihydroquinolones and 2-oxindoles as potential VEGFR-2 inhibitors: In-vitro anticancer evaluation and in … MS Taghour, H Elkady, WM Eldehna, NM El-Deeb, AM Kenawy, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1903-1917, 2022 | 74 | 2022 |
Design and discovery of new 1,2,4‐triazolo[4,3‐c]quinazolines as potential DNA intercalators and topoisomerase II inhibitors MS Alesawy, AA Al‐Karmalawy, EB Elkaeed, M Alswah, A Belal, ... Archiv Der Pharmazie 354 (3), 2000237, 2021 | 67 | 2021 |
Discovery and antiproliferative evaluation of new quinoxalines as potential DNA intercalators and topoisomerase II inhibitors IH Eissa, AM Metwaly, A Belal, ABM Mehany, RR Ayyad, K El‐Adl, ... Archiv der Pharmazie 352 (11), 1900123, 2019 | 65 | 2019 |
Design and Synthesis of New Quinoxaline Derivatives as Potential Histone Deacetylase Inhibitors Targeting Hepatocellular Carcinoma: In Silico, In Vitro, and SAR … C Ma, MS Taghour, A Belal, ABM Mehany, N Mostafa, A Nabeeh, IH Eissa, ... Frontiers in chemistry 9, 725135, 2021 | 60 | 2021 |
In Silico Studies of Some Isoflavonoids as Potential Candidates against COVID-19 Targeting Human ACE2 (hACE2) and Viral Main Protease (Mpro) MS Alesawy, AE Abdallah, MS Taghour, EB Elkaeed, I H. Eissa, ... Molecules 26 (9), 2806, 2021 | 56 | 2021 |
Discovery of new VEGFR-2 inhibitors based on bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as anticancer agents and apoptosis inducers NA Alsaif, MS Taghour, MM Alanazi, AJ Obaidullah, AA Al-Mehizia, ... Journal of enzyme inhibition and medicinal chemistry 36 (1), 1093-1114, 2021 | 45 | 2021 |
New quinoline and isatin derivatives as apoptotic VEGFR-2 inhibitors: design, synthesis, anti-proliferative activity, docking, ADMET, toxicity, and MD simulation studies EB Elkaeed, MS Taghour, HA Mahdy, WM Eldehna, NM El-Deeb, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2191-2205, 2022 | 42 | 2022 |
Discovery of new 3-methylquinoxalines as potential anti-cancer agents and apoptosis inducers targeting VEGFR-2: design, synthesis, and in silico studies MSTIIHEI Mohammed M. AlanaziORCID Icon,Elwan AlaaORCID Icon,Nawaf A ... Journal of Enzyme Inhibition and Medicinal Chemistry 36 (١), 1732-1750, 2021 | 39 | 2021 |
Design, synthesis, anti-proliferative evaluation, docking, and MD simulations studies of new thiazolidine-2, 4-diones targeting VEGFR-2 and apoptosis pathway MS Taghour, H Elkady, WM Eldehna, N El-Deeb, AM Kenawy, ... PLoS One 17 (9), e0272362, 2022 | 33 | 2022 |
Modified benzoxazole-based VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, and anti-proliferative evaluation A Elwan, AE Abdallah, HA Mahdy, MA Dahab, MS Taghour, EB Elkaeed, ... Molecules 27 (15), 5047, 2022 | 31 | 2022 |
Benzoxazole derivatives as new VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, in silico studies, and antiproliferative evaluation MS Taghour, HA Mahdy, MH Gomaa, A Aglan, MG Eldeib, A Elwan, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2063-2077, 2022 | 28 | 2022 |
Identification of new [1,2,4]triazolo[4,3-a]quinoxalines as potent VEGFR-2 tyrosine kinase inhibitors: design, synthesis, anticancer evaluation, and in silico studies HAM Nawaf A. Alsaif, Mohammed S. Taghour, Mohammed M. Alanazi, Ahmad J ... Bioorganic & Medicinal Chemistry, 2021 | 24 | 2021 |
Discovery of 2, 4-thiazolidinedione-tethered coumarins as novel selective inhibitors for carbonic anhydrase IX and XII isoforms WM Eldehna, MS Taghour, T Al-Warhi, A Nocentini, MM Elbadawi, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 531-541, 2022 | 20 | 2022 |
Design, synthesis and docking studies of new hydrazinyl-thiazole derivatives as anticancer and antimicrobial agents AM El-Naggar, A Zidan, EB Elkaeed, MS Taghour, WA Badawi Journal of Saudi Chemical Society 26 (4), 101488, 2022 | 19 | 2022 |
Design, synthesis, and biological evaluation of novel bioactive thalidomide analogs as anticancer immunomodulatory agents AR Kotb, DA Bakhotmah, AE Abdallah, H Elkady, MS Taghour, IH Eissa, ... RSC advances 12 (52), 33525-33539, 2022 | 18 | 2022 |
Discovery of new quinoline and isatine derivatives as potential VEGFR-2 inhibitors: Design, synthesis, antiproliferative, docking and MD simulation studies MS Taghour, H Elkady, WM Eldehna, N El-Deeb, AM Kenawy, ... Journal of Biomolecular Structure and Dynamics 41 (21), 11535-11550, 2023 | 16 | 2023 |
Targeting VEGFR‐2 by new quinoxaline derivatives: Design, synthesis, antiproliferative assay, apoptosis induction, and in silico studies NA Alsaif, HA Mahdy, MM Alanazi, AJ Obaidullah, HM Alkahtani, ... Archiv der Pharmazie 355 (2), 2100359, 2022 | 14 | 2022 |