Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors HK Eltzschig, JC Ibla, GT Furuta, MO Leonard, KA Jacobson, K Enjyoji, ... The Journal of experimental medicine 198 (5), 783-796, 2003 | 597 | 2003 |
MicroRNA-155 promotes resolution of hypoxia-inducible factor 1α activity during prolonged hypoxia U Bruning, L Cerone, Z Neufeld, SF Fitzpatrick, A Cheong, CC Scholz, ... Molecular and cellular biology 31 (19), 4087-4096, 2011 | 343 | 2011 |
Reoxygenation‐specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia‐reperfusion injury MO Leonard, NE Kieran, K Howell, MJ Burne, R Varadarajan, ... The FASEB Journal 20 (14), 2624-2626, 2006 | 308 | 2006 |
Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia KM Comerford, MO Leonard, J Karhausen, R Carey, SP Colgan, ... Proceedings of the National Academy of Sciences 100 (3), 986-991, 2003 | 225 | 2003 |
The role of HIF-1α in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia MO Leonard, DC Cottell, C Godson, HR Brady, CT Taylor Journal of Biological Chemistry 278 (41), 40296-40304, 2003 | 195 | 2003 |
Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress A Wilmes, A Limonciel, L Aschauer, K Moenks, C Bielow, MO Leonard, ... Journal of proteomics 79, 180-194, 2013 | 194 | 2013 |
Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog NE Kieran, PP Doran, SB Connolly, MC Greenan, DF Higgins, M Leonard, ... Kidney international 64 (2), 480-492, 2003 | 185 | 2003 |
BRIEF COMMUNICATION-15-Epi-16-(Para-Fluorophenoxy)-Lipoxin A4-Methyl Ester, a Synthetic Analogue of 15-epi-Lipoxin A4, Is Protective in Experimental Ischemic Acute Renal Failure MO Leonard, K Hannan, MJ Burne, DWP Lappin, P Doran, P Coleman, ... Journal of the American Society of Nephrology 13 (6), 1657-1662, 2002 | 180* | 2002 |
An overview of transcriptional regulation in response to toxicological insult P Jennings, A Limonciel, L Felice, MO Leonard Archives of toxicology 87, 49-72, 2013 | 162 | 2013 |
Multi-method characterization of the human circulating microbiome E Whittle, MO Leonard, R Harrison, TW Gant, DP Tonge Frontiers in microbiology 9, 3266, 2019 | 147 | 2019 |
Role of MAP kinase pathways in mediating IL-6 production in human primary mesangial and proximal tubular cells M Leonard, MP Ryan, AJ Watson, H Schramek, E Healy Kidney international 56 (4), 1366-1377, 1999 | 145 | 1999 |
TGF-β superfamily members modulate growth, branching, shaping, and patterning of the ureteric bud KT Bush, H Sakurai, DL Steer, MO Leonard, RV Sampogna, TN Meyer, ... Developmental biology 266 (2), 285-298, 2004 | 140 | 2004 |
Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics A Wilmes, C Bielow, C Ranninger, P Bellwon, L Aschauer, A Limonciel, ... Toxicology in Vitro 30 (1), 117-127, 2015 | 139 | 2015 |
Potentiation of glucocorticoid activity in hypoxia through induction of the glucocorticoid receptor MO Leonard, C Godson, HR Brady, CT Taylor The Journal of Immunology 174 (4), 2250-2257, 2005 | 135 | 2005 |
Gremlin plays a key role in the pathogenesis of pulmonary hypertension E Cahill, CM Costello, SC Rowan, S Harkin, K Howell, MO Leonard, ... Circulation 125 (7), 920-930, 2012 | 126 | 2012 |
NF-κB links CO2 sensing to innate immunity and inflammation in mammalian cells EP Cummins, KM Oliver, CR Lenihan, SF Fitzpatrick, U Bruning, ... The Journal of Immunology 185 (7), 4439-4445, 2010 | 124 | 2010 |
Transforming growth factor‐β‐regulated gene transcription and protein expression in human GFAP‐negative lamina cribrosa cells RP Kirwan, MO Leonard, M Murphy, AF Clark, CJ O'Brien Glia 52 (4), 309-324, 2005 | 119 | 2005 |
Identification and dissection of the Nrf2 mediated oxidative stress pathway in human renal proximal tubule toxicity A Wilmes, D Crean, S Aydin, W Pfaller, P Jennings, MO Leonard Toxicology In Vitro 25 (3), 613-622, 2011 | 102 | 2011 |
Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes A Limonciel, L Aschauer, A Wilmes, S Prajczer, MO Leonard, W Pfaller, ... Toxicology in Vitro 25 (8), 1855-1862, 2011 | 93 | 2011 |
Delineation of the key aspects in the regulation of epithelial monolayer formation L Aschauer, LN Gruber, W Pfaller, A Limonciel, TJ Athersuch, R Cavill, ... Molecular and cellular biology 33 (13), 2535-2550, 2013 | 90 | 2013 |