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Jonathan Douros
Jonathan Douros
Indiana Biosciences Research Institute
在 indianabiosciences.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion
KA Anderson, FK Huynh, K Fisher-Wellman, JD Stuart, BS Peterson, ...
Cell metabolism 25 (4), 838-855. e15, 2017
3062017
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist
FS Willard, JD Douros, MBN Gabe, AD Showalter, DB Wainscott, ...
JCI insight 5 (17), 2020
2522020
Role for leptin in promoting glucose mobilization during acute hyperosmotic stress in teleost fishes
DA Baltzegar, BJ Reading, JD Douros, RJ Borski
J Endocrinol 220 (1), 61-72, 2014
942014
The effects of bariatric surgery on islet function, insulin secretion, and glucose control
JD Douros, J Tong, DA D’Alessio
Endocrine reviews 40 (5), 1394-1423, 2019
752019
Next generation GLP-1/GIP/glucagon triple agonists normalize body weight in obese mice
PJ Knerr, SA Mowery, JD Douros, B Premdjee, KR Hjøllund, Y He, ...
Molecular metabolism 63, 101533, 2022
702022
The limited role of glucagon for ketogenesis during fasting or in response to SGLT2 inhibition
ME Capozzi, RW Coch, J Koech, II Astapova, JB Wait, SE Encisco, ...
Diabetes 69 (5), 882-892, 2020
522020
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets
K El, JD Douros, FS Willard, A Novikoff, A Sargsyan, D Perez-Tilve, ...
Nature Metabolism 5 (6), 945-954, 2023
472023
Control of leptin by metabolic state and its regulatory interactions with pituitary growth hormone and hepatic growth hormone receptors and insulin like growth factors in the …
JD Douros, DA Baltzegar, J Mankiewicz, J Taylor, Y Yamaguchi, ...
General and comparative endocrinology 240, 227-237, 2017
442017
Sleeve gastrectomy rapidly enhances islet function independently of body weight
JD Douros, J Niu, S Sdao, T Gregg, K Fisher-Wellman, M Bharadwaj, ...
JCI insight 4 (6), 2019
382019
Enhanced glucose control following vertical sleeve gastrectomy does not require a β-cell glucagon-like peptide 1 receptor
JD Douros, AG Lewis, EP Smith, JJ Niu, M Capozzi, A Wittmann, ...
Diabetes 67 (8), 1504-1511, 2018
382018
Leptin stimulates hepatic growth hormone receptor and insulin-like growth factor gene expression in a teleost fish, the hybrid striped bass
ET Won, JD Douros, DA Hurt, RJ Borski
General and Comparative Endocrinology 229, 84-91, 2016
382016
Prolactin is a major inhibitor of hepatic leptin A synthesis and secretion: studies utilizing a homologous leptin A ELISA in the tilapia
JD Douros, DA Baltzegar, JP Breves, DT Lerner, AP Seale, EG Grau, ...
General and comparative endocrinology 207, 86-93, 2014
362014
Leptin stimulates cellular glycolysis through a STAT3 dependent mechanism in Tilapia
JD Douros, DA Baltzegar, BJ Reading, AP Seale, DT Lerner, EG Grau, ...
Frontiers in endocrinology 9, 465, 2018
322018
Discovery of a potent GIPR peptide antagonist that is effective in rodent and human systems
B Yang, VM Gelfanov, K El, A Chen, R Rohlfs, B DuBois, AMK Hansen, ...
Molecular Metabolism 66, 101638, 2022
222022
Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice
A Liskiewicz, A Khalil, D Liskiewicz, A Novikoff, G Grandl, G Maity-Kumar, ...
Nature Metabolism 5 (12), 2075-2085, 2023
212023
Epinephrine and glucose regulation of leptin synthesis and secretion in a teleost fish, the tilapia (Oreochromis mossambicus)
JL Mankiewicz, CA Deck, JD Taylor, JD Douros, RJ Borski
General and Comparative Endocrinology 302, 113669, 2021
172021
GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice
C Quarta, K Stemmer, A Novikoff, B Yang, F Klingelhuber, A Harger, ...
Nature Metabolism 4 (8), 1071-1083, 2022
152022
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist. JCI Insight. 2020
FS Willard, JD Douros, MB Gabe, AD Showalter, DB Wainscott, TM Suter, ...
Article 140532 (10.1172), 0
15
Optimization of truncated glucagon peptides to achieve selective, high potency, full antagonists
B Yang, VM Gelfanov, D Perez-Tilve, B DuBois, R Rohlfs, J Levy, ...
Journal of Medicinal Chemistry 64 (8), 4697-4708, 2021
132021
Temporal plasticity of insulin and incretin secretion and insulin sensitivity following sleeve gastrectomy contribute to sustained improvements in glucose control
JD Douros, J Niu, S Sdao, T Gregg, MJ Merrins, J Campbell, J Tong, ...
Molecular metabolism 28, 144-150, 2019
132019
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