SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion KA Anderson, FK Huynh, K Fisher-Wellman, JD Stuart, BS Peterson, ... Cell metabolism 25 (4), 838-855. e15, 2017 | 306 | 2017 |
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist FS Willard, JD Douros, MBN Gabe, AD Showalter, DB Wainscott, ... JCI insight 5 (17), 2020 | 252 | 2020 |
Role for leptin in promoting glucose mobilization during acute hyperosmotic stress in teleost fishes DA Baltzegar, BJ Reading, JD Douros, RJ Borski J Endocrinol 220 (1), 61-72, 2014 | 94 | 2014 |
The effects of bariatric surgery on islet function, insulin secretion, and glucose control JD Douros, J Tong, DA D’Alessio Endocrine reviews 40 (5), 1394-1423, 2019 | 75 | 2019 |
Next generation GLP-1/GIP/glucagon triple agonists normalize body weight in obese mice PJ Knerr, SA Mowery, JD Douros, B Premdjee, KR Hjøllund, Y He, ... Molecular metabolism 63, 101533, 2022 | 70 | 2022 |
The limited role of glucagon for ketogenesis during fasting or in response to SGLT2 inhibition ME Capozzi, RW Coch, J Koech, II Astapova, JB Wait, SE Encisco, ... Diabetes 69 (5), 882-892, 2020 | 52 | 2020 |
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets K El, JD Douros, FS Willard, A Novikoff, A Sargsyan, D Perez-Tilve, ... Nature Metabolism 5 (6), 945-954, 2023 | 47 | 2023 |
Control of leptin by metabolic state and its regulatory interactions with pituitary growth hormone and hepatic growth hormone receptors and insulin like growth factors in the … JD Douros, DA Baltzegar, J Mankiewicz, J Taylor, Y Yamaguchi, ... General and comparative endocrinology 240, 227-237, 2017 | 44 | 2017 |
Sleeve gastrectomy rapidly enhances islet function independently of body weight JD Douros, J Niu, S Sdao, T Gregg, K Fisher-Wellman, M Bharadwaj, ... JCI insight 4 (6), 2019 | 38 | 2019 |
Enhanced glucose control following vertical sleeve gastrectomy does not require a β-cell glucagon-like peptide 1 receptor JD Douros, AG Lewis, EP Smith, JJ Niu, M Capozzi, A Wittmann, ... Diabetes 67 (8), 1504-1511, 2018 | 38 | 2018 |
Leptin stimulates hepatic growth hormone receptor and insulin-like growth factor gene expression in a teleost fish, the hybrid striped bass ET Won, JD Douros, DA Hurt, RJ Borski General and Comparative Endocrinology 229, 84-91, 2016 | 38 | 2016 |
Prolactin is a major inhibitor of hepatic leptin A synthesis and secretion: studies utilizing a homologous leptin A ELISA in the tilapia JD Douros, DA Baltzegar, JP Breves, DT Lerner, AP Seale, EG Grau, ... General and comparative endocrinology 207, 86-93, 2014 | 36 | 2014 |
Leptin stimulates cellular glycolysis through a STAT3 dependent mechanism in Tilapia JD Douros, DA Baltzegar, BJ Reading, AP Seale, DT Lerner, EG Grau, ... Frontiers in endocrinology 9, 465, 2018 | 32 | 2018 |
Discovery of a potent GIPR peptide antagonist that is effective in rodent and human systems B Yang, VM Gelfanov, K El, A Chen, R Rohlfs, B DuBois, AMK Hansen, ... Molecular Metabolism 66, 101638, 2022 | 22 | 2022 |
Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice A Liskiewicz, A Khalil, D Liskiewicz, A Novikoff, G Grandl, G Maity-Kumar, ... Nature Metabolism 5 (12), 2075-2085, 2023 | 21 | 2023 |
Epinephrine and glucose regulation of leptin synthesis and secretion in a teleost fish, the tilapia (Oreochromis mossambicus) JL Mankiewicz, CA Deck, JD Taylor, JD Douros, RJ Borski General and Comparative Endocrinology 302, 113669, 2021 | 17 | 2021 |
GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice C Quarta, K Stemmer, A Novikoff, B Yang, F Klingelhuber, A Harger, ... Nature Metabolism 4 (8), 1071-1083, 2022 | 15 | 2022 |
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist. JCI Insight. 2020 FS Willard, JD Douros, MB Gabe, AD Showalter, DB Wainscott, TM Suter, ... Article 140532 (10.1172), 0 | 15 | |
Optimization of truncated glucagon peptides to achieve selective, high potency, full antagonists B Yang, VM Gelfanov, D Perez-Tilve, B DuBois, R Rohlfs, J Levy, ... Journal of Medicinal Chemistry 64 (8), 4697-4708, 2021 | 13 | 2021 |
Temporal plasticity of insulin and incretin secretion and insulin sensitivity following sleeve gastrectomy contribute to sustained improvements in glucose control JD Douros, J Niu, S Sdao, T Gregg, MJ Merrins, J Campbell, J Tong, ... Molecular metabolism 28, 144-150, 2019 | 13 | 2019 |