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Organoid models of human and mouse ductal pancreatic cancer SF Boj, CI Hwang, LA Baker, IIC Chio, DD Engle, V Corbo, M Jager, ... Cell 160 (1), 324-338, 2015 | 1965 | 2015 |
Enhancer reprogramming promotes pancreatic cancer metastasis JS Roe, CI Hwang, TDD Somerville, JP Milazzo, EJ Lee, B Da Silva, ... Cell 170 (5), 875-888. e20, 2017 | 393 | 2017 |
Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche A Flesken-Nikitin, CI Hwang, CY Cheng, TV Michurina, G Enikolopov, ... Nature 495 (7440), 241-245, 2013 | 387 | 2013 |
Frequent downregulation of miR-34 family in human ovarian cancers DC Corney, CI Hwang, A Matoso, M Vogt, A Flesken-Nikitin, AK Godwin, ... Clinical Cancer Research 16 (4), 1119-1128, 2010 | 384 | 2010 |
Wild-type p53 controls cell motility and invasion by dual regulation of MET expression CI Hwang, A Matoso, DC Corney, A Flesken-Nikitin, S Körner, W Wang, ... Proceedings of the National Academy of Sciences 108 (34), 14240-14245, 2011 | 157 | 2011 |
Identification of radiation-specific responses from gene expression profile WY Park, CI Hwang, CN Im, MJ Kang, JH Woo, JH Kim, YS Kim, JH Kim, ... Oncogene 21 (55), 8521-8528, 2002 | 132 | 2002 |
Preclinical models of pancreatic ductal adenocarcinoma CI Hwang, SF Boj, H Clevers, DA Tuveson The Journal of pathology 238 (2), 197-204, 2016 | 116 | 2016 |
miR-34 cooperates with p53 in suppression of prostate cancer by joint regulation of stem cell compartment CY Cheng, CI Hwang, DC Corney, A Flesken-Nikitin, L Jiang, GM Öner, ... Cell reports 6 (6), 1000-1007, 2014 | 111 | 2014 |
Intraductal transplantation models of human pancreatic ductal adenocarcinoma reveal progressive transition of molecular subtypes K Miyabayashi, LA Baker, A Deschênes, B Traub, G Caligiuri, D Plenker, ... Cancer discovery 10 (10), 1566-1589, 2020 | 107 | 2020 |
SOAT1 promotes mevalonate pathway dependency in pancreatic cancer TE Oni, G Biffi, LA Baker, Y Hao, C Tonelli, TDD Somerville, A Deschênes, ... Journal of Experimental Medicine 217 (9), e20192389, 2020 | 80 | 2020 |
Gene profile of replicative senescence is different from progeria or elderly donor WY Park, CI Hwang, MJ Kang, JY Seo, JH Chung, YS Kim, JH Lee, H Kim, ... Biochemical and Biophysical Research Communications 282 (4), 934-939, 2001 | 78 | 2001 |
GADD153 mediates celecoxib-induced apoptosis in cervical cancer cells SH Kim, CI Hwang, YS Juhnn, JH Lee, WY Park, YS Song Carcinogenesis 28 (1), 223-231, 2007 | 74 | 2007 |
Caveolin-1 upregulation in senescent neurons alters amyloid precursor protein processing MJ Kang, YH Chung, CI Hwang, M Murata, T Fujimoto, IH Mook-Jung, ... Experimental & molecular medicine 38 (2), 126-133, 2006 | 74 | 2006 |
Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade SR Nielsen, JE Strøbech, ER Horton, R Jackstadt, A Laitala, MC Bravo, ... Nature Communications 12 (1), 3414, 2021 | 71 | 2021 |
Gene expression profiling of anti-GBM glomerulonephritis model: the role of NF-κB in immune complex kidney disease JH Kim, IS Ha, CI Hwang, YJ Lee, J Kim, SH Yang, YS Kim, YA Cao, ... Kidney international 66 (5), 1826-1837, 2004 | 71 | 2004 |
Model organoids provide new research opportunities for ductal pancreatic cancer SF Boj, CI Hwang, LA Baker, DD Engle, DA Tuveson, H Clevers Molecular & cellular oncology 3 (1), e1014757, 2016 | 70 | 2016 |
Adenovirus-TRAIL can overcome TRAIL resistance and induce a bystander effect JY Seol, KH Park, CI Hwang, WY Park, CG Yoo, YW Kim, SK Han, ... Cancer gene therapy 10 (7), 540-548, 2003 | 61 | 2003 |
FOXO3a turns the tumor necrosis factor receptor signaling towards apoptosis through reciprocal regulation of c-Jun N-terminal kinase and NF-κB HY Lee, SW Youn, JY Kim, KW Park, CI Hwang, WY Park, BH Oh, YB Park, ... Arteriosclerosis, thrombosis, and vascular biology 28 (1), 112-120, 2008 | 59 | 2008 |
Identification of resistance pathways specific to malignancy using organoid models of pancreatic cancer M Ponz-Sarvise, V Corbo, H Tiriac, DD Engle, KK Frese, TE Oni, ... Clinical Cancer Research 25 (22), 6742-6755, 2019 | 54 | 2019 |