Integrated bioprocesses K Schügerl, J Hubbuch Current opinion in microbiology 8 (3), 294-300, 2005 | 171 | 2005 |
High throughput screening of chromatographic phases for rapid process development M Bensch, P Schulze Wierling, E von Lieres, J Hubbuch Chemical Engineering & Technology: Industrial Chemistry‐Plant Equipment …, 2005 | 147 | 2005 |
High‐gradient magnetic affinity separation of trypsin from porcine pancreatin JJ Hubbuch, ORT Thomas Biotechnology and bioengineering 79 (3), 301-313, 2002 | 140 | 2002 |
Effects of ionic strength and mobile phase pH on the binding orientation of lysozyme on different ion-exchange adsorbents F Dismer, M Petzold, J Hubbuch Journal of Chromatography A 1194 (1), 11-21, 2008 | 139 | 2008 |
High throughput screening for the design and optimization of chromatographic processes–miniaturization, automation and parallelization of breakthrough and elution studies M Wiendahl, P Schulze Wierling, J Nielsen, D Fomsgaard Christensen, ... Chemical Engineering & Technology: Industrial Chemistry‐Plant Equipment …, 2008 | 139 | 2008 |
High throughput screening techniques in downstream processing: Preparation, characterization and optimization of aqueous two-phase systems M Bensch, B Selbach, J Hubbuch Chemical Engineering Science 62 (7), 2011-2021, 2007 | 135 | 2007 |
High gradient magnetic separation versus expanded bed adsorption: a first principle comparison JJ Hubbuch, DB Matthiesen, TJ Hobley, ORT Thomas Bioseparation 10, 99-112, 2001 | 128 | 2001 |
Rational and systematic protein purification process development: the next generation BK Nfor, PDEM Verhaert, LAM van der Wielen, J Hubbuch, M Ottens Trends in biotechnology 27 (12), 673-679, 2009 | 127 | 2009 |
Mechanism and kinetics of protein transport in chromatographic media studied by confocal laser scanning microscopy: Part I. The interplay of sorbent structure and fluid phase … J Hubbuch, T Linden, E Knieps, A Ljunglöf, J Thömmes, MR Kula Journal of Chromatography A 1021 (1-2), 93-104, 2003 | 119 | 2003 |
Next generation vaccines and vectors: Designing downstream processes for recombinant protein‐based virus‐like particles CL Effio, J Hubbuch Biotechnology journal 10 (5), 715-727, 2015 | 113 | 2015 |
Biomass/adsorbent electrostatic interactions in expanded bed adsorption: a zeta potential study DQ Lin, PJ Brixius, JJ Hubbuch, J Thömmes, MR Kula Biotechnology and bioengineering 83 (2), 149-157, 2003 | 112 | 2003 |
A novel approach to characterize the binding orientation of lysozyme on ion-exchange resins F Dismer, J Hubbuch Journal of Chromatography A 1149 (2), 312-320, 2007 | 107 | 2007 |
Application of an aqueous two‐phase systems high‐throughput screening method to evaluate mAb HCP separation SA Oelmeier, F Dismer, J Hubbuch Biotechnology and bioengineering 108 (1), 69-81, 2011 | 102 | 2011 |
Determination of parameters for the steric mass action model—A comparison between two approaches A Osberghaus, S Hepbildikler, S Nath, M Haindl, E von Lieres, J Hubbuch Journal of Chromatography A 1233, 54-65, 2012 | 98 | 2012 |
A critical review of recent trends, and a future perspective of optical spectroscopy as PAT in biopharmaceutical downstream processing L Rolinger, M Ruedt, J Hubbuch Analytical and bioanalytical chemistry 412, 2047-2064, 2020 | 95 | 2020 |
3D structure-based protein retention prediction for ion-exchange chromatography F Dismer, J Hubbuch Journal of Chromatography A 1217 (8), 1343-1353, 2010 | 94 | 2010 |
Molecular dynamics simulations on aqueous two-phase systems-Single PEG-molecules in solution SA Oelmeier, F Dismer, J Hubbuch BMC biophysics 5, 1-13, 2012 | 92 | 2012 |
Advances in downstream processing of biologics–spectroscopy: an emerging process analytical technology M Rüdt, T Briskot, J Hubbuch Journal of Chromatography A 1490, 2-9, 2017 | 88 | 2017 |
Downstream processing of virus-like particles: Single-stage and multi-stage aqueous two-phase extraction CL Effio, L Wenger, O Ötes, SA Oelmeier, R Kneusel, J Hubbuch Journal of Chromatography A 1383, 35-46, 2015 | 88 | 2015 |
Dynamics of protein uptake within the adsorbent particle during packed bed chromatography J Hubbuch, T Linden, E Knieps, J Thömmes, MR Kula Biotechnology and bioengineering 80 (4), 359-368, 2002 | 88 | 2002 |