The role of amyloid-β oligomers in toxicity, propagation, and immunotherapy U Sengupta, AN Nilson, R Kayed EBioMedicine 6, 42-49, 2016 | 732 | 2016 |
Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice CA Lasagna-Reeves, DL Castillo-Carranza, U Sengupta, AL Clos, ... Molecular neurodegeneration 6, 1-14, 2011 | 617 | 2011 |
Identification of oligomers at early stages of tau aggregation in Alzheimer's disease CA Lasagna-Reeves, DL Castillo-Carranza, U Sengupta, J Sarmiento, ... The FASEB Journal 26 (5), 1946, 2012 | 554 | 2012 |
Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau CA Lasagna-Reeves, DL Castillo-Carranza, U Sengupta, ... Scientific reports 2 (1), 700, 2012 | 547 | 2012 |
Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles DL Castillo-Carranza, U Sengupta, MJ Guerrero-Muñoz, ... Journal of Neuroscience 34 (12), 4260-4272, 2014 | 302 | 2014 |
Specific targeting of tau oligomers in htau mice prevents cognitive impairment and tau toxicity following injection with brain-derived tau oligomeric seeds DL Castillo-Carranza, JE Gerson, U Sengupta, MJ Guerrero-Muñoz, ... Journal of Alzheimer's Disease 40 (s1), S97-S111, 2014 | 188 | 2014 |
Pathological interface between oligomeric alpha-synuclein and tau in synucleinopathies U Sengupta, MJ Guerrero-Muñoz, DL Castillo-Carranza, ... Biological psychiatry 78 (10), 672-683, 2015 | 179 | 2015 |
Tau oligomers associate with inflammation in the brain and retina of tauopathy mice and in neurodegenerative diseases AN Nilson, KC English, JE Gerson, T Barton Whittle, C Nicolas Crain, ... Journal of Alzheimer's Disease 55 (3), 1083-1099, 2017 | 166 | 2017 |
Rapid accumulation of endogenous tau oligomers in a rat model of traumatic brain injury: possible link between traumatic brain injury and sporadic tauopathies BE Hawkins, S Krishnamurthy, DL Castillo-Carranza, U Sengupta, ... Journal of Biological Chemistry 288 (23), 17042-17050, 2013 | 163 | 2013 |
Tau immunotherapy modulates both pathological tau and upstream amyloid pathology in an Alzheimer's disease mouse model DL Castillo-Carranza, MJ Guerrero-Muñoz, U Sengupta, C Hernandez, ... Journal of Neuroscience 35 (12), 4857-4868, 2015 | 153 | 2015 |
Soluble tau aggregates, not large fibrils, are the toxic species that display seeding and cross‐seeding behavior G Ghag, N Bhatt, DV Cantu, MJ Guerrero‐Munoz, A Ellsworth, ... Protein Science 27 (11), 1901-1909, 2018 | 112 | 2018 |
Amyloid β, Tau, and α-Synuclein aggregates in the pathogenesis, prognosis, and therapeutics for neurodegenerative diseases U Sengupta, R Kayed Progress in Neurobiology 214, 102270, 2022 | 110 | 2022 |
Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer’s disease and frontotemporal dementia S Gaikwad, N Puangmalai, A Bittar, M Montalbano, S Garcia, S McAllen, ... Cell reports 36 (3), 2021 | 108 | 2021 |
Cerebral microvascular accumulation of tau oligomers in Alzheimer’s disease and related tauopathies DL Castillo-Carranza, AN Nilson, CE Van Skike, JB Jahrling, K Patel, ... Aging and disease 8 (3), 257, 2017 | 105 | 2017 |
TDP-43 Phosphorylation by casein kinase Iε promotes oligomerization and enhances toxicity in vivo DK Choksi, B Roy, S Chatterjee, T Yusuff, MF Bakhoum, U Sengupta, ... Human molecular genetics 23 (4), 1025-1035, 2014 | 104 | 2014 |
Tau oligomers derived from traumatic brain injury cause cognitive impairment and accelerate onset of pathology in Htau mice J Gerson, DL Castillo-Carranza, U Sengupta, R Bodani, DS Prough, ... Journal of neurotrauma 33 (22), 2034-2043, 2016 | 102 | 2016 |
Characterization of tau oligomeric seeds in progressive supranuclear palsy JE Gerson, U Sengupta, CA Lasagna-Reeves, MJ Guerrero-Muñoz, ... Acta neuropathologica communications 2, 1-9, 2014 | 100 | 2014 |
Dual role of p53 amyloid formation in cancer; loss of function and gain of toxicity CA Lasagna-Reeves, AL Clos, D Castillo-Carranza, U Sengupta, ... Biochemical and biophysical research communications 430 (3), 963-968, 2013 | 98 | 2013 |
Tau oligomers in cerebrospinal fluid in Alzheimer's disease U Sengupta, E Portelius, O Hansson, K Farmer, D Castillo‐Carranza, ... Annals of clinical and translational neurology 4 (4), 226-235, 2017 | 89 | 2017 |
Expression-based network biology identifies alteration in key regulatory pathways of type 2 diabetes and associated risk/complications U Sengupta, S Ukil, N Dimitrova, S Agrawal PloS one 4 (12), e8100, 2009 | 85 | 2009 |