Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13639* | 2021 |
Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis SJ Barmada, G Skibinski, E Korb, EJ Rao, JY Wu, S Finkbeiner Journal of Neuroscience 30 (2), 639-649, 2010 | 636 | 2010 |
Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models SJ Barmada, A Serio, A Arjun, B Bilican, A Daub, DM Ando, A Tsvetkov, ... Nature chemical biology 10 (8), 677-685, 2014 | 478 | 2014 |
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy A Serio, B Bilican, SJ Barmada, DM Ando, C Zhao, R Siller, K Burr, ... Proceedings of the National Academy of Sciences 110 (12), 4697-4702, 2013 | 423 | 2013 |
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability B Bilican, A Serio, SJ Barmada, AL Nishimura, GJ Sullivan, M Carrasco, ... Proceedings of the National Academy of Sciences 109 (15), 5803-5808, 2012 | 421 | 2012 |
Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury LH Martens, J Zhang, SJ Barmada, P Zhou, S Kamiya, B Sun, SW Min, ... The Journal of clinical investigation 122 (11), 3955-3959, 2012 | 333 | 2012 |
ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects H Qiu, S Lee, Y Shang, WY Wang, KF Au, S Kamiya, SJ Barmada, ... The Journal of clinical investigation 124 (3), 981-999, 2014 | 315 | 2014 |
Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models M Armakola, MJ Higgins, MD Figley, SJ Barmada, EA Scarborough, ... Nature genetics 44 (12), 1302-1309, 2012 | 280 | 2012 |
RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response KM Green, MR Glineburg, MG Kearse, BN Flores, AE Linsalata, SJ Fedak, ... Nature communications 8 (1), 2005, 2017 | 239 | 2017 |
Proteostasis of polyglutamine varies among neurons and predicts neurodegeneration AS Tsvetkov, M Arrasate, S Barmada, DM Ando, P Sharma, BA Shaby, ... Nature chemical biology 9 (9), 586-592, 2013 | 199 | 2013 |
Mutant prion proteins are partially retained in the endoplasmic reticulum L Ivanova, S Barmada, T Kummer, DA Harris Journal of Biological Chemistry 276 (45), 42409-42421, 2001 | 163 | 2001 |
TDP43 nuclear export and neurodegeneration in models of amyotrophic lateral sclerosis and frontotemporal dementia HC Archbold, KL Jackson, A Arora, K Weskamp, EMH Tank, X Li, ... Scientific reports 8 (1), 4606, 2018 | 153 | 2018 |
Abnormal RNA stability in amyotrophic lateral sclerosis EM Tank, C Figueroa-Romero, LM Hinder, K Bedi, HC Archbold, X Li, ... Nature communications 9 (1), 2845, 2018 | 151 | 2018 |
Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1 SJ Barmada, S Ju, A Arjun, A Batarse, HC Archbold, D Peisach, X Li, ... Proceedings of the National Academy of Sciences 112 (25), 7821-7826, 2015 | 146 | 2015 |
Autophagy and ALS: mechanistic insights and therapeutic implications JP Chua, H De Calbiac, E Kabashi, SJ Barmada Autophagy 18 (2), 254-282, 2022 | 122 | 2022 |
Shortened TDP43 isoforms upregulated by neuronal hyperactivity drive TDP43 pathology in ALS K Weskamp, EM Tank, R Miguez, JP McBride, NB Gómez, M White, Z Lin, ... The Journal of clinical investigation 130 (3), 1139-1155, 2020 | 117 | 2020 |
Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization AM Malik, RA Miguez, X Li, YS Ho, EL Feldman, SJ Barmada elife 7, e35977, 2018 | 107 | 2018 |
An intramolecular salt bridge linking TDP43 RNA binding, protein stability, and TDP43-dependent neurodegeneration BN Flores, X Li, AM Malik, J Martinez, AA Beg, SJ Barmada Cell reports 27 (4), 1133-1150. e8, 2019 | 94 | 2019 |
GFP-tagged prion protein is correctly localized and functionally active in the brains of transgenic mice S Barmada, P Piccardo, K Yamaguchi, B Ghetti, DA Harris Neurobiology of disease 16 (3), 527-537, 2004 | 92 | 2004 |
Pathogenic TARDBP mutations in amyotrophic lateral sclerosis and frontotemporal dementia: disease-associated pathways SJ Barmada, S Finkbeiner Reviews in the Neurosciences 21 (4), 251-272, 2010 | 77 | 2010 |