关注
Bryan Mackowiak
Bryan Mackowiak
National Institute on Alcohol Abuse and Alcoholism
在 umaryland.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
MicroRNAs as regulators, biomarkers and therapeutic targets in liver diseases
X Wang, Y He, B Mackowiak, B Gao
Gut 70 (4), 784-795, 2021
2612021
Mechanisms of xenobiotic receptor activation: Direct vs. indirect
B Mackowiak, H Wang
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1859 (9 …, 2016
1192016
The roles of xenobiotic receptors: beyond chemical disposition
B Mackowiak, J Hodge, S Stern, H Wang
Drug Metabolism and Disposition 46 (9), 1361-1371, 2018
942018
Genome-wide analysis of human constitutive androstane receptor (CAR) transcriptome in wild-type and CAR-knockout HepaRG cells
D Li, B Mackowiak, TG Brayman, M Mitchell, L Zhang, SM Huang, H Wang
Biochemical pharmacology 98 (1), 190-202, 2015
562015
Identification of modulators that activate the constitutive androstane receptor from the Tox21 10K compound library
C Lynch, B Mackowiak, R Huang, L Li, S Heyward, S Sakamuru, H Wang, ...
Toxicological Sciences 167 (1), 282-292, 2019
322019
Mechanistic insights of phenobarbital-mediated activation of human but not mouse pregnane X receptor
L Li, MA Welch, Z Li, B Mackowiak, S Heyward, PW Swaan, H Wang
Molecular Pharmacology 96 (3), 345-354, 2019
272019
E-selectin-dependent inflammation and lipolysis in adipose tissue exacerbate steatosis-to-NASH progression via S100A8/9
RM Rodrigues, Y He, S Hwang, A Bertola, B Mackowiak, YA Ahmed, ...
Cellular and molecular gastroenterology and hepatology 13 (1), 151-171, 2022
222022
Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure
J Ma, A Guillot, Z Yang, B Mackowiak, S Hwang, O Park, BJ Peiffer, ...
The Journal of Clinical Investigation 132 (14), 2022
212022
Hepatic injury and inflammation alter ethanol metabolism and drinking behavior
T Ren, B Mackowiak, Y Lin, Y Gao, J Niu, B Gao
Food and Chemical Toxicology 136, 111070, 2020
152020
Interleukin-20 exacerbates acute hepatitis and bacterial infection by downregulating IκBζ target genes in hepatocytes
Y He, D Feng, S Hwang, B Mackowiak, X Wang, X Xiang, RM Rodrigues, ...
Journal of hepatology 75 (1), 163-176, 2021
142021
Molecular basis of metabolism-mediated conversion of PK11195 from an antagonist to an agonist of the constitutive androstane receptor
B Mackowiak, L Li, MA Welch, D Li, JW Jones, S Heyward, MA Kane, ...
Molecular Pharmacology 92 (1), 75-87, 2017
132017
Human constitutive androstane receptor agonist DL5016: A novel sensitizer for cyclophosphamide-based chemotherapies
D Liang, L Li, C Lynch, B Mackowiak, WD Hedrich, Y Ai, Y Yin, S Heyward, ...
European journal of medicinal chemistry 179, 84-99, 2019
122019
MicroRNA-223 attenuates hepatocarcinogenesis by blocking hypoxia-driven angiogenesis and immunosuppression
Y Fu, B Mackowiak, D Feng, H Lu, Y Guan, T Lehner, H Pan, XW Wang, ...
Gut, 2023
82023
High-content analysis of constitutive androstane receptor (CAR) translocation identifies mosapride citrate as a CAR agonist that represses gluconeogenesis
B Mackowiak, L Li, C Lynch, A Ziman, S Heyward, M Xia, H Wang
Biochemical pharmacology 168, 224-236, 2019
72019
Ethanol and its Nonoxidative Metabolites Promote Acute Liver Injury by Inducing ER Stress, Adipocyte Death, and Lipolysis
SH Park, W Seo, MJ Xu, B Mackowiak, Y Lin, Y He, Y Fu, S Hwang, ...
Cellular and molecular gastroenterology and hepatology 15 (2), 281-306, 2023
52023
Activation of VIPR1 suppresses hepatocellular carcinoma progression by regulating arginine and pyrimidine metabolism
Y Fu, S Liu, RM Rodrigues, Y Han, C Guo, Z Zhu, Y He, B Mackowiak, ...
International Journal of Biological Sciences 18 (11), 4341, 2022
52022
Mechanistic Analysis of an Extracellular Signal–Regulated Kinase 2–Interacting Compound that Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative Stress
R Martinez, W Huang, R Samadani, B Mackowiak, G Centola, L Chen, ...
Journal of Pharmacology and Experimental Therapeutics 376 (1), 84-97, 2021
42021
CITCO as an adjuvant facilitates CHOP-based lymphoma treatment in hCAR-transgenic mice
R Kurian, W Hedrich, B Mackowiak, L Li, H Wang
Cells 9 (11), 2520, 2020
42020
High-content analysis of constitutive androstane receptor nuclear translocation
B Mackowiak, H Wang
Nuclear Receptors: Methods and Experimental Protocols, 71-77, 2019
32019
Inverted culture plate system for cellular co-culture
B Mackowiak, H Wang, L Li
US Patent 11,608,483, 2023
12023
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