Combination therapy with histone deacetylase inhibitors (HDACi) for the treatment of cancer: achieving the full therapeutic potential of HDACi A Suraweera, KJ O’Byrne, DJ Richard Frontiers in oncology 8, 92, 2018 | 655 | 2018 |
Failure of amino acid homeostasis causes cell death following proteasome inhibition A Suraweera, C Münch, A Hanssum, A Bertolotti Molecular cell 48 (2), 242-253, 2012 | 344 | 2012 |
Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage A Suraweera, OJ Becherel, P Chen, N Rundle, R Woods, J Nakamura, ... The Journal of cell biology 177 (6), 969-979, 2007 | 212 | 2007 |
Functional role for senataxin, defective in ataxia oculomotor apraxia type 2, in transcriptional regulation A Suraweera, YC Lim, R Woods, GW Birrell, T Nasim, OJ Becherel, ... Human molecular genetics 18 (18), 3384-3396, 2009 | 194 | 2009 |
Senataxin plays an essential role with DNA damage response proteins in meiotic recombination and gene silencing OJ Becherel, AJ Yeo, A Stellati, EYH Heng, J Luff, AM Suraweera, ... PLoS genetics 9 (4), e1003435, 2013 | 172 | 2013 |
Chemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promising C Jekimovs, E Bolderson, A Suraweera, M Adams, KJ O’Byrne, ... Frontiers in oncology 4, 86, 2014 | 139 | 2014 |
Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks E Bolderson, E Petermann, L Croft, A Suraweera, RK Pandita, TK Pandita, ... Nucleic acids research 42 (10), 6326-6336, 2014 | 61 | 2014 |
Néstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation N Paquet, JK Box, NW Ashton, A Suraweera, LV Croft, AJ Urquhart, ... BMC molecular biology 15, 1-11, 2014 | 54 | 2014 |
Nucleolar localization of aprataxin is dependent on interaction with nucleolin and on active ribosomal DNA transcription OJ Becherel, N Gueven, GW Birrell, V Schreiber, A Suraweera, B Jakob, ... Human molecular genetics 15 (14), 2239-2249, 2006 | 52 | 2006 |
Cell metabolism and DNA repair pathways: implications for cancer therapy T Sobanski, M Rose, A Suraweera, K O’Byrne, DJ Richard, E Bolderson Frontiers in cell and developmental biology 9, 633305, 2021 | 48 | 2021 |
Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage E Bolderson, JT Burgess, J Li, NS Gandhi, D Boucher, LV Croft, S Beard, ... Nature communications 10 (1), 5501, 2019 | 47 | 2019 |
Epigenetic mechanisms in DNA double strand break repair: A clinical review A Fernandez, C O’Leary, KJ O’Byrne, J Burgess, DJ Richard, ... Frontiers in Molecular Biosciences 8, 685440, 2021 | 32 | 2021 |
Defining COMMD4 as an anti-cancer therapeutic target and prognostic factor in non-small cell lung cancer A Suraweera, A Duff, MN Adams, C Jekimovs, PHG Duijf, C Liu, ... British Journal of Cancer 123 (4), 591-603, 2020 | 19 | 2020 |
Elevating CDCA3 levels in non-small cell lung cancer enhances sensitivity to platinum-based chemotherapy K Kildey, NS Gandhi, KB Sahin, ET Shah, E Boittier, PHG Duijf, C Molloy, ... Communications Biology 4 (1), 638, 2021 | 18 | 2021 |
Barrier-to-autointegration-factor (Banf1) modulates DNA double-strand break repair pathway choice via regulation of DNA-dependent kinase (DNA-PK) activity JT Burgess, CM Cheong, A Suraweera, T Sobanski, S Beard, K Dave, ... Nucleic Acids Research 49 (6), 3294-3307, 2021 | 18 | 2021 |
Redox regulation in the base excision repair pathway: old and new players as cancer therapeutic targets A Rajapakse, A Suraweera, D Boucher, A Naqi, K O'Byrne, DJ Richard, ... Current Medicinal Chemistry 27 (12), 1901-1921, 2020 | 12 | 2020 |
COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double strand breaks A Suraweera, N Gandhi, S Beard, J Burgess, T, L Croft, V, E Bolderson, ... Communications Biology 4 (1), 1-11, 2021 | 11 | 2021 |
COMMD1, from the repair of DNA double strand breaks, to a novel anti-cancer therapeutic target A Suraweera, PHG Duijf, C Jekimovs, K Schrobback, C Liu, MN Adams, ... Cancers 13 (4), 830, 2021 | 4 | 2021 |
The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA-PKcs and ATM kinase activity to regulate DNA double-strand break repair T Sobanski, A Suraweera, JT Burgess, I Richard, CM Cheong, K Dave, ... Scientific Reports 13 (1), 15171, 2023 | 3 | 2023 |
Cancer Therapeutics: Targeting DNA Repair Pathways A Suraweera, JAL Brown, YC Lim, MF Lavin Frontiers in Molecular Biosciences, 122, 2022 | 2 | 2022 |