Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons M Nagai, DB Re, T Nagata, A Chalazonitis, TM Jessell, H Wichterle, ... Nature neuroscience 10 (5), 615-622, 2007 | 1457 | 2007 |
Necroptosis drives motor neuron death in models of both sporadic and familial ALS DB Re, V Le Verche, C Yu, MW Amoroso, KA Politi, S Phani, B Ikiz, ... Neuron 81 (5), 1001-1008, 2014 | 470 | 2014 |
The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice DC Wu, DB Ré, M Nagai, H Ischiropoulos, S Przedborski Proceedings of the National Academy of Sciences 103 (32), 12132-12137, 2006 | 333 | 2006 |
Inflammation in ALS and SMA: sorting out the good from the evil D Papadimitriou, V Le Verche, A Jacquier, B Ikiz, S Przedborski, DB Re Neurobiology of disease 37 (3), 493-502, 2010 | 176 | 2010 |
Fractalkine: moving from chemotaxis to neuroprotection D Bérangère Ré, S Przedborski Nature neuroscience 9 (7), 859-861, 2006 | 113 | 2006 |
Sex-specific neurotoxic effects of heavy metal pollutants: Epidemiological, experimental evidence and candidate mechanisms M Gade, N Comfort, DB Re Environmental research 201, 111558, 2021 | 94 | 2021 |
Is spinal muscular atrophy a disease of the motor neurons only: pathogenesis and therapeutic implications? C Simone, A Ramirez, M Bucchia, P Rinchetti, H Rideout, D Papadimitriou, ... Cellular and molecular life sciences 73, 1003-1020, 2016 | 76 | 2016 |
Mutant superoxide dismutase 1 (SOD1), a cause of amyotrophic lateral sclerosis, disrupts the recruitment of SMN, the spinal muscular atrophy protein to nuclear Cajal bodies S Kariya, DB Re, A Jacquier, K Nelson, S Przedborski, UR Monani Human molecular genetics 21 (15), 3421-3434, 2012 | 65 | 2012 |
The regulatory machinery of neurodegeneration in in vitro models of amyotrophic lateral sclerosis B Ikiz, MJ Alvarez, DB Ré, V Le Verche, K Politi, F Lotti, S Phani, ... Cell reports 12 (2), 335-345, 2015 | 57 | 2015 |
Importance of astrocytic inactivation of synaptically released glutamate for cell survival in the central nervous system—are astrocytes vulnerable to low intracellular … L Had-Aissouni, DB Ré, A Nieoullon, L Kerkerian-Le Goff Journal of Physiology-Paris 96 (3-4), 317-322, 2002 | 57 | 2002 |
Glutamate transport alteration triggers differentiation‐state selective oxidative death of cultured astrocytes: a mechanism different from excitotoxicity depending on … DB Ré, J Boucraut, D Samuel, S Birman, L Kerkerian‐Le Goff, ... Journal of neurochemistry 85 (5), 1159-1170, 2003 | 55 | 2003 |
Sex-specific neurotoxic effects of organophosphate pesticides across the life course N Comfort, DB Re Current environmental health reports 4, 392-404, 2017 | 53 | 2017 |
Organophosphate neurotoxicity to the voluntary motor system on the trail of environment-caused amyotrophic lateral sclerosis: the known, the misknown, and the unknown SJ Merwin, T Obis, Y Nunez, DB Re Archives of toxicology 91, 2939-2952, 2017 | 52 | 2017 |
The role of the innate immune system in ALS S Phani, DB Re, S Przedborski Frontiers in pharmacology 3, 150, 2012 | 50 | 2012 |
Preferential vulnerability of mesencephalic dopamine neurons to glutamate transporter dysfunction I Nafia, DB Re, F Masmejean, C Melon, P Kachidian, L Kerkerian‐Le Goff, ... Journal of neurochemistry 105 (2), 484-496, 2008 | 46 | 2008 |
Fine particle exposure and clinical aggravation in neurodegenerative diseases in New York State Y Nunez, AK Boehme, MG Weisskopf, DB Re, A Navas-Acien, ... Environmental health perspectives 129 (2), 027003, 2021 | 45 | 2021 |
Systematic elucidation of neuron-astrocyte interaction in models of amyotrophic lateral sclerosis using multi-modal integrated bioinformatics workflow V Mishra, DB Re, V Le Verche, MJ Alvarez, A Vasciaveo, A Jacquier, ... Nature communications 11 (1), 5579, 2020 | 37 | 2020 |
A motif within the armadillo repeat of Parkinson’s-linked LRRK2 interacts with FADD to hijack the extrinsic death pathway N Antoniou, D Vlachakis, A Memou, E Leandrou, PE Valkimadi, ... Scientific reports 8 (1), 3455, 2018 | 34 | 2018 |
Glutamate leakage from a compartmentalized intracellular metabolic pool and activation of the lipoxygenase pathway mediate oxidative astrocyte death by reversed glutamate transport DB Re, I Nafia, C Melon, K Shimamoto, LKL Goff, L Had‐Aissouni Glia 54 (1), 47-57, 2006 | 34 | 2006 |
Limitations and Challenges in Modeling Diseases Involving Spinal Motor Neuron Degeneration in Vitro M Bucchia, SJ Merwin, DB Re, S Kariya Frontiers in cellular neuroscience 12, 61, 2018 | 33 | 2018 |