Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ... Nature communications 10 (1), 2674, 2019 | 291 | 2019 |
Discovery of drug synergies in gastric cancer cells predicted by logical modeling Å Flobak, A Baudot, E Remy, L Thommesen, D Thieffry, M Kuiper, ... PLoS computational biology 11 (8), e1004426, 2015 | 129 | 2015 |
Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking AM Sofias, YC Toner, AE Meerwaldt, MMT van Leent, G Soultanidis, ... ACS nano 14 (7), 7832-7846, 2020 | 81 | 2020 |
The gastrin and cholecystokinin receptors mediated signaling network: a scaffold for data analysis and new hypotheses on regulatory mechanisms S Tripathi, Å Flobak, K Chawla, A Baudot, T Bruland, L Thommesen, ... BMC Systems Biology 9, 1-15, 2015 | 60 | 2015 |
A high-throughput drug combination screen of targeted small molecule inhibitors in cancer cell lines Å Flobak, B Niederdorfer, VT Nakstad, L Thommesen, G Klinkenberg, ... Scientific data 6 (1), 237, 2019 | 39 | 2019 |
High-throughput screening reveals higher synergistic effect of MEK inhibitor combinations in colon cancer spheroids E Folkesson, B Niederdorfer, VT Nakstad, L Thommesen, G Klinkenberg, ... Scientific reports 10 (1), 11574, 2020 | 33 | 2020 |
Network and systems medicine: Position paper of the european collaboration on science and technology action on open multiscale systems medicine B Comte, J Baumbach, A Benis, J Basílio, N Debeljak, Å Flobak, ... Network and systems medicine 3 (1), 67-90, 2020 | 29 | 2020 |
The minimum information about a molecular interaction causal statement (MI2CAST) V Touré, S Vercruysse, ML Acencio, RC Lovering, S Orchard, G Bradley, ... Bioinformatics 36 (24), 5712-5718, 2020 | 19 | 2020 |
The status of causality in biological databases: data resources and data retrieval possibilities to support logical modeling V Touré, Å Flobak, A Niarakis, S Vercruysse, M Kuiper Briefings in bioinformatics 22 (4), bbaa390, 2021 | 18 | 2021 |
CImbinator: a web-based tool for drug synergy analysis in small-and large-scale datasets Å Flobak, M Vazquez, A Lægreid, A Valencia Bioinformatics 33 (15), 2410-2412, 2017 | 16 | 2017 |
A middle-out modeling strategy to extend a colon cancer logical model improves drug synergy predictions in epithelial-derived cancer cell lines E Tsirvouli, V Touré, B Niederdorfer, M Vázquez, Å Flobak, M Kuiper Frontiers in molecular biosciences 7, 502573, 2020 | 13 | 2020 |
Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway Å Helland, HG Russnes, GL Fagereng, K Al-Shibli, Y Andersson, T Berg, ... Journal of translational medicine 20 (1), 225, 2022 | 12 | 2022 |
Strategies to enhance logic modeling-based cell line-specific drug synergy prediction B Niederdorfer, V Touré, M Vazquez, L Thommesen, M Kuiper, A Lægreid, ... Frontiers in physiology 11, 862, 2020 | 12 | 2020 |
Functional precision cancer medicine: drug sensitivity screening enabled by cell culture models Å Flobak, SS Skånland, E Hovig, K Taskén, HG Russnes Trends in Pharmacological Sciences 43 (11), 973-985, 2022 | 11 | 2022 |
A national precision cancer medicine implementation initiative for Norway K Taskén, HEG Russnes, E Aas, L Bjørge, ES Blix, E Enerly, GL Fagereng, ... Nature Medicine 28 (5), 885-887, 2022 | 10 | 2022 |
Boolean function metrics can assist modelers to check and choose logical rules J Zobolas, PT Monteiro, M Kuiper, Å Flobak Journal of Theoretical Biology 538, 111025, 2022 | 7 | 2022 |
Tumor targeting by αvβ3-integrin-specific lipid nanoparticles occurs via phagocyte hitchhiking, ACS Nano 14 (2020) 7832–7846 AM Sofias, YC Toner, AE Meerwaldt, MMT van Leent, G Soultanidis, ... | 7 | |
Systematic review: predictive value of organoids in colorectal cancer BC Sakshaug, E Folkesson, TH Haukaas, T Visnes, Å Flobak Scientific Reports 13 (1), 18124, 2023 | 6 | 2023 |
Synergistic effects of complex drug combinations in colorectal cancer cells predicted by logical modelling E Folkesson, BC Sakshaug, AD Hoel, G Klinkenberg, Å Flobak Frontiers in Systems Biology 3, 1112831, 2023 | 5 | 2023 |
Characterisation of colorectal cancer cell lines through proteomic profiling of their extracellular vesicles KA Heck, HT Lindholm, B Niederdorfer, E Tsirvouli, M Kuiper, Å Flobak, ... Proteomes 11 (1), 3, 2023 | 5 | 2023 |