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John Jason Morton
John Jason Morton
Assistant Research Professor, University of Colorado, AMC
在 ucdenver.edu 的电子邮件经过验证
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引用次数
引用次数
年份
Induction and repair of zinc-finger nuclease-targeted double-strand breaks in Caenorhabditis elegans somatic cells
J Morton, MW Davis, EM Jorgensen, D Carroll
Proceedings of the National Academy of Sciences 103 (44), 16370-16375, 2006
2562006
Design, construction and in vitro testing of zinc finger nucleases
D Carroll, JJ Morton, KJ Beumer, DJ Segal
Nature protocols 1 (3), 1329-1341, 2006
2562006
Humanized mouse xenograft models: narrowing the tumor–microenvironment gap
JJ Morton, G Bird, Y Refaeli, A Jimeno
Cancer research 76 (21), 6153-6158, 2016
2542016
A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins
SB Keysar, DP Astling, RT Anderson, BW Vogler, DW Bowles, JJ Morton, ...
Molecular oncology 7 (4), 776-790, 2013
1742013
Gene Activation Using FLP Recombinase in C. elegans
MW Davis, JJ Morton, D Carroll, EM Jorgensen
PLoS genetics 4 (3), e1000028, 2008
1532008
XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer
JJ Morton, G Bird, SB Keysar, DP Astling, TR Lyons, RT Anderson, ...
Oncogene 35 (3), 290-300, 2016
1372016
Cancer cell CD44 mediates macrophage/monocyte-driven regulation of head and neck cancer stem cells
KE Gomez, FL Wu, SB Keysar, JJ Morton, B Miller, TS Chimed, PN Le, ...
Cancer research 80 (19), 4185-4198, 2020
1352020
Regulation of head and neck squamous cancer stem cells by PI3K and SOX2
SB Keysar, PN Le, B Miller, BC Jackson, JR Eagles, C Nieto, J Kim, ...
Journal of the National Cancer Institute 109 (1), djw189, 2017
1222017
Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer
SB Keysar, PN Le, RT Anderson, JJ Morton, DW Bowles, JJ Paylor, ...
Cancer research 73 (11), 3381-3392, 2013
1062013
Zinc-finger directed double-strand breaks within CAG repeat tracts promote repeat instability in human cells
D Mittelman, C Moye, J Morton, K Sykoudis, Y Lin, D Carroll, JH Wilson
Proceedings of the National Academy of Sciences 106 (24), 9607-9612, 2009
1062009
Hedgehog signaling drives radioresistance and stroma-driven tumor repopulation in head and neck squamous cancers
GN Gan, J Eagles, SB Keysar, G Wang, MJ Glogowska, C Altunbas, ...
Cancer research 74 (23), 7024-7036, 2014
752014
Gene Targeting in Drosophila and Caenorhabditis elegans With Zinc-Finger Nucleases
D Carroll, KJ Beumer, JJ Morton, A Bozas, JK Trautman
Chromosomal Mutagenesis, 63-77, 2008
662008
The transcription start site landscape of C. elegans
TL Saito, S Hashimoto, SG Gu, JJ Morton, M Stadler, T Blumenthal, A Fire, ...
Genome research 23 (8), 1348-1361, 2013
652013
Wnt signaling dynamics in head and neck squamous cell cancer tumor‐stroma interactions
PN Le, SB Keysar, B Miller, JR Eagles, TS Chimed, J Reisinger, ...
Molecular carcinogenesis 58 (3), 398-410, 2019
602019
The dual pathway inhibitor rigosertib is effective in direct patient tumor xenografts of head and neck squamous cell carcinomas
RT Anderson, SB Keysar, DW Bowles, MJ Glogowska, DP Astling, ...
Molecular cancer therapeutics 12 (10), 1994-2005, 2013
362013
Salivary gland cancer patient-derived xenografts enable characterization of cancer stem cells and new gene events associated with tumor progression
SB Keysar, JR Eagles, B Miller, BC Jackson, FN Chowdhury, J Reisinger, ...
Clinical Cancer Research 24 (12), 2935-2943, 2018
312018
Generation of functional human thymic cells from induced pluripotent stem cells
HA Ramos, S.A., Morton, J.J., Yadav, P., Reed, B., Alizadeh, S.I., Shilleh ...
J Allergy Clin Immunol, 2021
25*2021
Dual use of hematopoietic and mesenchymal stem cells enhances engraftment and immune cell trafficking in an allogeneic humanized mouse model of head and neck cancer
JJ Morton, SB Keysar, L Perrenoud, TS Chimed, J Reisinger, B Jackson, ...
Molecular carcinogenesis 57 (11), 1651-1663, 2018
222018
Expansion of Human and Murine Hematopoietic Stem and Progenitor Cells Ex Vivo without Genetic Modification Using MYC and Bcl-2 Fusion Proteins
GA Bird, A Polsky, P Estes, T Hanlon, H Hamilton, JJ Morton, J Gutman, ...
PloS one 9 (8), e105525, 2014
222014
RNA processing in C. elegans
JJ Morton, T Blumenthal
Methods in cell biology 106, 187-217, 2011
222011
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