Ethaselen: a potent mammalian thioredoxin reductase 1 inhibitor and novel organoselenium anticancer agent L Wang, Z Yang, J Fu, H Yin, K Xiong, Q Tan, H Jin, J Li, T Wang, W Tang, ... Free Radical Biology and Medicine 52 (5), 898-908, 2012 | 167 | 2012 |
Inhibition of thioredoxin reductase by a novel series of bis-1, 2-benzisoselenazol-3 (2H)-ones: Organoselenium compounds for cancer therapy J He, D Li, K Xiong, Y Ge, H Jin, G Zhang, M Hong, Y Tian, J Yin, H Zeng Bioorganic & medicinal chemistry 20 (12), 3816-3827, 2012 | 95 | 2012 |
Selenium-containing thioredoxin reductase inhibitor ethaselen sensitizes non-small cell lung cancer to radiotherapy L Wang, J Fu, J Wang, C Jin, X Ren, Q Tan, J Li, H Yin, K Xiong, T Wang, ... Anti-Cancer Drugs 22 (8), 732-740, 2011 | 46 | 2011 |
Thioredxin reductase inhibitor ethaselen increases the drug sensitivity of the colon cancer cell line LoVo towards cisplatin via regulation of G1 phase and reversal of G2/M … J Fu, J Li, Q Tan, H Yin, K Xiong, T Wang, X Ren, H Zeng Investigational new drugs 29, 627-636, 2011 | 30 | 2011 |
The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models J Rozowsky, J Gao, B Borsari, YT Yang, T Galeev, G Gursoy, CB Epstein, ... Cell 186 (7), 1493-1511, 2023 | 24 | 2023 |
High transcriptional error rates vary as a function of gene expression level KM Meer, PG Nelson, K Xiong, J Masel Genome Biology and Evolution 12 (1), 3754-3761, 2020 | 15 | 2020 |
Drift barriers to quality control when genes are expressed at different levels K Xiong, JP McEntee, DJ Porfirio, J Masel Genetics 205 (1), 397-407, 2017 | 15 | 2017 |
Feed-forward regulation adaptively evolves via dynamics rather than topology when there is intrinsic noise K Xiong, AK Lancaster, ML Siegal, J Masel Nature communications 10 (1), 2418, 2019 | 12 | 2019 |
Novel mechanism of ethaselen in poorly differentiated colorectal RKO cell growth inhibition: Simultaneous regulation of TrxR transcription, expression and enzyme activity H Yin, J Li, K Xiong, L Wang, T Wang, Q Tan, J Fu, X Ren, H Zeng Differentiation 81 (1), 49-56, 2011 | 12 | 2011 |
Differences in evolutionary accessibility determine which equally effective regulatory motif evolves to generate pulses K Xiong, M Gerstein, J Masel Genetics 219 (3), iyab140, 2021 | 9 | 2021 |
Multi-tissue integrative analysis of personal epigenomes J Rozowsky, J Drenkow, Y Yang, G Gursoy, T Galeev, B Borsari, ... | 7 | 2021 |
Initiate tumors with single cell spheres formed in serum-containing medium G Zhang, K Xiong, W Ma, W Xu, H Zeng Journal of Cancer 6 (9), 901, 2015 | 5 | 2015 |
Reactive oxygen species mediate ethaselen-induced rapid apoptosis in A549 cells K Xiong, W Xu, H Zeng Journal of Chinese Pharmaceutical Sciences 23 (1), 54, 2014 | 4 | 2014 |
Non-adaptive factors determine which equally effective regulatory motif evolves to generate pulses K Xiong, M Gerstein, J Masel bioRxiv, 2020.12. 02.409151, 2020 | 1 | 2020 |
Comparing technological development and biological evolution from a network perspective KK Yan, D Wang, K Xiong, M Gerstein Cell Systems 10 (3), 219-222, 2020 | 1 | 2020 |
Drift barriers for the proofreading of genes expressed at different levels K Xiong, JP McEntee, DJ Porfirio, J Masel bioRxiv, 058453, 2016 | 1 | 2016 |
Assessing tissue-specific effects of rare and structural variants towards gene regulation with the EN-Tex personal genome resource M Jensen, T Michaels, A Su, T Galeev, S Kumar, K Xiong, B Borsari, ... EUROPEAN JOURNAL OF HUMAN GENETICS 32, 45-46, 2024 | | 2024 |
The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models J Rozowsky, J Drenkow, YT Yang, G Gursoy, T Galeev, B Borsari, ... bioRxiv, 2021.04. 26.441442, 2021 | | 2021 |
Adaptive and Non-Adaptive Evolution of the Control of Gene Expression K Xiong The University of Arizona, 2019 | | 2019 |