Pancreatic cancers require autophagy for tumor growth S Yang, X Wang, G Contino, M Liesa, E Sahin, H Ying, A Bause, Y Li, ... Genes & development 25 (7), 717-729, 2011 | 1606 | 2011 |
Telomere dysfunction induces metabolic and mitochondrial compromise E Sahin, S Colla, M Liesa, J Moslehi, FL Müller, M Guo, M Cooper, ... Nature 470 (7334), 359, 2011 | 1395 | 2011 |
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice M Jaskelioff, FL Muller, JH Paik, E Thomas, S Jiang, AC Adams, E Sahin, ... Nature 469 (7328), 102-106, 2011 | 1016 | 2011 |
Linking functional decline of telomeres, mitochondria and stem cells during ageing E Sahin, RA DePinho nature 464 (7288), 520-528, 2010 | 873 | 2010 |
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells B Gan, J Hu, S Jiang, Y Liu, E Sahin, L Zhuang, E Fletcher-Sananikone, ... Nature 468 (7324), 701-704, 2010 | 469 | 2010 |
Axis of ageing: telomeres, p53 and mitochondria E Sahin, RA DePinho Nature reviews Molecular cell biology 13 (6), 397-404, 2012 | 419 | 2012 |
Passenger deletions generate therapeutic vulnerabilities in cancer FL Muller, S Colla, E Aquilanti, VE Manzo, G Genovese, J Lee, ... Nature 488 (7411), 337-342, 2012 | 363 | 2012 |
Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer J Hu, SS Hwang, M Liesa, B Gan, E Sahin, M Jaskelioff, Z Ding, H Ying, ... Cell 148 (4), 651-663, 2012 | 343 | 2012 |
PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas H Zheng, H Ying, R Wiedemeyer, H Yan, SN Quayle, EV Ivanova, JH Paik, ... Cancer cell 17 (5), 497-509, 2010 | 277 | 2010 |
mTORC1-dependent and-independent regulation of stem cell renewal, differentiation, and mobilization B Gan, E Sahin, S Jiang, A Sanchez-Aguilera, KL Scott, L Chin, ... Proceedings of the National Academy of Sciences 105 (49), 19384-19389, 2008 | 219 | 2008 |
Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer AC Kimmelman, AF Hezel, AJ Aguirre, H Zheng, J Paik, H Ying, GC Chu, ... Proceedings of the National Academy of Sciences 105 (49), 19372-19377, 2008 | 186 | 2008 |
Telomeres and mitochondria in the aging heart J Moslehi, RA DePinho, E Sahin Circulation research 110 (9), 1226-1237, 2012 | 169 | 2012 |
Telomere dysfunction induces sirtuin repression that drives telomere-dependent disease H Amano, A Chaudhury, C Rodriguez-Aguayo, L Lu, V Akhanov, A Catic, ... Cell metabolism 29 (6), 1274-1290. e9, 2019 | 144 | 2019 |
Soluble collagen VI drives serum-starved fibroblasts through S phase and prevents apoptosis via down-regulation of Bax M Ruhl, E Sahin, M Johannsen, R Somasundaram, D Manski, ... Journal of Biological Chemistry 274 (48), 34361-34368, 1999 | 144 | 1999 |
DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse RS Maser, KK Wong, E Sahin, H Xia, M Naylor, HM Hedberg, SE Artandi, ... Molecular and cellular biology, 2007 | 88 | 2007 |
Mitochondrial transporter ATP binding cassette mitochondrial erythroid is a novel gene required for cardiac recovery after ischemia/reperfusion M Liesa, I Luptak, F Qin, BB Hyde, E Sahin, DA Siwik, Z Zhu, DR Pimentel, ... Circulation 124 (7), 806-813, 2011 | 78 | 2011 |
A chemical chaperone improves muscle function in mice with a RyR1 mutation CS Lee, AD Hanna, H Wang, A Dagnino-Acosta, AD Joshi, M Knoblauch, ... Nature communications 8 (1), 14659, 2017 | 67 | 2017 |
Soluble collagen VI induces tyrosine phosphorylation of paxillin and focal adhesion kinase and activates the MAP kinase erk2 in fibroblasts M Rühl, M Johannsen, J Atkinson, D Manski, E Sahin, R Somasundaram, ... Experimental cell research 250 (2), 548-557, 1999 | 61 | 1999 |
DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer R Matsunuma, DW Chan, BJ Kim, P Singh, A Han, AB Saltzman, C Cheng, ... Proceedings of the National Academy of Sciences 115 (51), E11978-E11987, 2018 | 45 | 2018 |
Adult autoimmune enteropathy treated successfully with tacrolimus S Daum, E Sahin, A Jansen, B Heine, EO Riecken, M Zeitz, W Schmidt Digestion 68 (2-3), 86-90, 2003 | 41 | 2003 |