Phosphinic acid compounds in biochemistry, biology and medicine M Collinsova, J Jiracek Current medicinal chemistry 7 (6), 629-647, 2000 | 271 | 2000 |
RXP 407, a phosphinic peptide, is a potent inhibitor of angiotensin I converting enzyme able to differentiate between its two active sites V Dive, J Cotton, A Yiotakis, A Michaud, S Vassiliou, J Jiracek, G Vazeux, ... Proceedings of the National Academy of Sciences 96 (8), 4330-4335, 1999 | 220 | 1999 |
Betaine-homocysteine methyltransferase: zinc in a distorted barrel JC Evans, DP Huddler, J Jiracek, C Castro, NS Millian, TA Garrow, ... Structure 10 (9), 1159-1171, 2002 | 149 | 2002 |
Development of Highly Potent and Selective Phosphinic Peptide Inhibitors of Zinc Endopeptidase 24-15 Using Combinatorial Chemistry (∗) J Jirácek, A Yiotakis, B Vincent, A Lecoq, A Nicolaou, F Checler, V Dive Journal of Biological Chemistry 270 (37), 21701-21706, 1995 | 134 | 1995 |
Insulin and insulin-like growth factor II differentially regulate endocytic sorting and stability of insulin receptor isoform A A Morcavallo, M Genua, A Palummo, E Kletvikova, J Jiracek, ... Journal of Biological Chemistry 287 (14), 11422-11436, 2012 | 95 | 2012 |
Inhibition of betaine-homocysteine S-methyltransferase causes hyperhomocysteinemia in mice M Collinsova, J Strakova, J Jiracek, TA Garrow The Journal of nutrition 136 (6), 1493-1497, 2006 | 81 | 2006 |
Dissecting the Catalytic Mechanism of Betaine−Homocysteine S-Methyltransferase by Use of Intrinsic Tryptophan Fluorescence and Site-Directed Mutagenesis C Castro, AA Gratson, JC Evans, J Jiracek, M Collinsová, ML Ludwig, ... Biochemistry 43 (18), 5341-5351, 2004 | 50 | 2004 |
Determination of dissociation constant of phosphinate group in phosphinic pseudopeptides by capillary zone electrophoresis D Koval, V Kašička, J Jiráček, M Collinsová, TA Garrow Journal of Chromatography B 770 (1-2), 145-154, 2002 | 50 | 2002 |
Effect of a novel selective and potent phosphinic peptide inhibitor of endopeptidase 3.4. 24.16 on neurotensin-induced analgesia and neuronal inactivation B Vincent, J Jiracek, F Noble, M Loog, B Roques, V Dive, JP Vincent, ... British journal of pharmacology 121 (4), 705, 1997 | 45 | 1997 |
Insight into the structural and biological relevance of the T/R transition of the N-terminus of the B-chain in human insulin L Kosinová, V Veverka, P Novotná, M Collinsová, M Urbanová, NR Moody, ... Biochemistry 53 (21), 3392-3402, 2014 | 43 | 2014 |
Examination of the role of endopeptidase 3.4.24.15 in Aβ secretion by human transfected cells N Chevallier, J Jiracek, B Vincent, CP Baur, MG Spillantini, M Goedert, ... British journal of pharmacology 121 (3), 556-562, 1997 | 43 | 1997 |
Insulin analogues with modifications at position B26. Divergence of binding affinity and biological activity L Zˇáková, L Kazdová, I Hanclová, E Protivínská, M Šanda, ... Biochemistry 47 (21), 5858-5868, 2008 | 41 | 2008 |
Dietary intake of S-(α-carboxybutyl)-dl-homocysteine induces hyperhomocysteinemia in rats J Strakova, KT Williams, S Gupta, KL Schalinske, WD Kruger, R Rozen, ... Nutrition research 30 (7), 492-500, 2010 | 38 | 2010 |
S-Alkylated Homocysteine Derivatives: New Inhibitors of Human Betaine-Homocysteine S-Methyltransferase J Jiracek, M Collinsova, I Rosenberg, M Budesinsky, E Protivinska, ... Journal of medicinal chemistry 49 (13), 3982-3989, 2006 | 38 | 2006 |
Combining combinatorial chemistry and affinity chromatography: highly selective inhibitors of human betaine: homocysteine S-methyltransferase M Collinsová, C Castro, TA Garrow, A Yiotakis, V Dive, J Jiráček Chemistry & biology 10 (2), 113-122, 2003 | 35 | 2003 |
Theory of the correlation between capillary and free-flow zone electrophoresis and its use for the conversion of analytical capillary separations to continuous free-flow … V Kasicka, Z Prusik, P Sazelova, J Jiracek, T Barth Journal of Chromatography-A 796 (1), 211, 1998 | 35 | 1998 |
Can arginine inhibit insulin aggregation? A combined protein crystallography, capillary electrophoresis, and molecular simulation study K Březina, E Duboué-Dijon, V Palivec, J Jiráček, T Křížek, CM Viola, ... The Journal of Physical Chemistry B 122 (44), 10069-10076, 2018 | 33 | 2018 |
Insulin–insulin-like growth factors hybrids as molecular probes of hormone: receptor binding specificity K Křížková, M Chrudinová, A Povalová, I Selicharová, M Collinsová, ... Biochemistry 55 (21), 2903-2913, 2016 | 32 | 2016 |
The development of a versatile trifunctional scaffold for biological applications V Vaněk, J Pícha, B Fabre, M Buděšínský, M Lepšík, J Jiráček European Journal of Organic Chemistry 2015 (17), 3689-3701, 2015 | 30 | 2015 |
Synthesis and evaluation of a library of trifunctional scaffold-derived compounds as modulators of the insulin receptor B Fabre, J Pícha, V Vaněk, I Selicharová, M Chrudinová, M Collinsová, ... ACS Combinatorial Science 18 (12), 710-722, 2016 | 29 | 2016 |