The organic chemistry of β-lactams GI Georg (No Title), 1993 | 487 | 1993 |
A convenient method for the efficient removal of ruthenium byproducts generated during olefin metathesis reactions YM Ahn, KL Yang, GI Georg Organic Letters 3 (9), 1411-1413, 2001 | 314 | 2001 |
The ecstasy and agony of assay interference compounds C Aldrich, C Bertozzi, GI Georg, L Kiessling, C Lindsley, D Liotta, ... ACS Chemical Neuroscience 8 (3), 420-423, 2017 | 300 | 2017 |
Efficient and practical asymmetric synthesis of the taxol C-13 side chain, N-benzoyl-(2R, 3S)-3-phenylisoserine, and its analogs via chiral 3-hydroxy-4-aryl-. beta.-lactams … I Ojima, I Habus, M Zhao, GI Georg, LR Jayasinghe The Journal of Organic Chemistry 56 (5), 1681-1683, 1991 | 280 | 1991 |
A preclinical evaluation of Minnelide as a therapeutic agent against pancreatic cancer R Chugh, V Sangwan, SP Patil, V Dudeja, RK Dawra, S Banerjee, ... Science translational medicine 4 (156), 156ra139-156ra139, 2012 | 256 | 2012 |
Mild and Selective Hydrozirconation of Amides to Aldehydes Using Cp2Zr(H)Cl: Scope and Mechanistic Insight JT Spletstoser, JM White, AR Tunoori, GI Georg Journal of the American Chemical Society 129 (11), 3408-3419, 2007 | 241 | 2007 |
Acetyl-lysine binding site of bromodomain-containing protein 4 (BRD4) interacts with diverse kinase inhibitors SWJ Ember, JY Zhu, SH Olesen, MP Martin, A Becker, N Berndt, GI Georg, ... ACS chemical biology 9 (5), 1160-1171, 2014 | 238 | 2014 |
" hydrophobic collapse" of taxol and Taxotere solution conformations in mixtures of water and organic solvent DG Vander Velde, GI Georg, GL Grunewald, CW Gunn, LA Mitscher Journal of the American Chemical Society 115 (24), 11650-11651, 1993 | 198 | 1993 |
Palladium (II)-catalyzed direct arylation of enaminones using organotrifluoroborates H Ge, MJ Niphakis, GI Georg Journal of the American Chemical Society 130 (12), 3708-3709, 2008 | 187 | 2008 |
Discovery of a potential allosteric ligand binding site in CDK2 S Betzi, R Alam, M Martin, DJ Lubbers, H Han, SR Jakkaraj, GI Georg, ... ACS chemical biology 6 (5), 492-501, 2011 | 186 | 2011 |
A Novel and Expeditious Reduction of Tertiary Amides to Aldehydes Using Cp2Zr(H)Cl JM White, AR Tunoori, GI Georg Journal of the American Chemical Society 122 (48), 11995-11996, 2000 | 186 | 2000 |
Synthesis of biologically active taxol analogs with modified phenylisoserine side chains GI Georg, ZS Cheruvallath, RH Himes, MR Mejillano, CT Burke Journal of medicinal chemistry 35 (22), 4230-4237, 1992 | 176 | 1992 |
Taxane anticancer agents: basic science and current status GI Georg, TT Chen, I Ojima, DM Vyas American Chemical Society, 1994 | 169 | 1994 |
Cyclin-dependent kinase inhibitor dinaciclib interacts with the acetyl-lysine recognition site of bromodomains MP Martin, SH Olesen, GI Georg, E Schönbrunn ACS chemical biology 8 (11), 2360-2365, 2013 | 160 | 2013 |
Asymmetric synthesis of (1'R, 3R, 4R)-4-acetoxy-3-[1'-((tert-butyldimethylsilyl) oxy) ethyl]-2-azetidinone and other 3-(1'-hydroxyethyl)-2-azetidinones from (S)-(+)-ethyl 3 … GI Georg, J Kant, HS Gill Journal of the American Chemical Society 109 (4), 1129-1135, 1987 | 157 | 1987 |
Epothilone and paclitaxel: unexpected differences in promoting the assembly and stabilization of yeast microtubules CJ Bode, ML Gupta, EA Reiff, KA Suprenant, GI Georg, RH Himes Biochemistry 41 (12), 3870-3874, 2002 | 156 | 2002 |
Polymer-bound triphenylphosphine as traceless reagent for Mitsunobu reactions in combinatorial chemistry: Synthesis of aryl ethers from phenols and alcohols AR Tunoori, D Dutta, GI Georg Tetrahedron letters 39 (48), 8751-8754, 1998 | 145 | 1998 |
The cryptophycins: their synthesis and anticancer activity MJ Eggen, GI Georg Medicinal research reviews 22 (2), 85-101, 2002 | 143 | 2002 |
β-Amyloid-induced neurodegeneration and protection by structurally diverse microtubule-stabilizing agents ML Michaelis, S Ansar, Y Chen, ER Reiff, KI Seyb, RH Himes, KL Audus, ... Journal of Pharmacology and Experimental Therapeutics 312 (2), 659-668, 2005 | 130 | 2005 |
Understanding tubulin–Taxol interactions: mutations that impart Taxol binding to yeast tubulin ML Gupta Jr, CJ Bode, GI Georg, RH Himes Proceedings of the National Academy of Sciences 100 (11), 6394-6397, 2003 | 129 | 2003 |