Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c DG Kirsch, A Doseff, BN Chau, DS Lim, NC de Souza-Pinto, R Hansford, ... Journal of Biological Chemistry 274 (30), 21155-21161, 1999 | 635 | 1999 |
Monocytes and macrophages regulate immunity through dynamic networks of survival and cell death A Parihar, TD Eubank, AI Doseff Journal of innate immunity 2 (3), 204-215, 2010 | 399 | 2010 |
Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-κB through the suppression of p65 phosphorylation C Nicholas, S Batra, MA Vargo, OH Voss, MA Gavrilin, MD Wewers, ... The Journal of Immunology 179 (10), 7121-7127, 2007 | 397 | 2007 |
Flavones: from biosynthesis to health benefits N Jiang, AI Doseff, E Grotewold Plants 5 (2), 27, 2016 | 305 | 2016 |
Macrophage colony-stimulating factor promotes cell survival through Akt/protein kinase B TW Kelley, MM Graham, AI Doseff, RW Pomerantz, SM Lau, MC Ostrowski, ... Journal of Biological Chemistry 274 (37), 26393-26398, 1999 | 208 | 1999 |
Binding of caspase-3 prodomain to heat shock protein 27 regulates monocyte apoptosis by inhibiting caspase-3 proteolytic activation OH Voss, S Batra, SJ Kolattukudy, ME Gonzalez-Mejia, JB Smith, ... Journal of Biological Chemistry 282 (34), 25088-25099, 2007 | 206 | 2007 |
Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization A Akhter, K Caution, AA Khweek, M Tazi, BA Abdulrahman, ... Immunity 37 (1), 35-47, 2012 | 203 | 2012 |
Apigenin-induced-apoptosis is mediated by the activation of PKCδ and caspases in leukemia cells MA Vargo, OH Voss, F Poustka, AJ Cardounel, E Grotewold, AI Doseff Biochemical pharmacology 72 (6), 681-692, 2006 | 202 | 2006 |
Spontaneous human monocyte apoptosis utilizes a caspase-3-dependent pathway that is blocked by endotoxin and is independent of caspase-1 RJ Fahy, AI Doseff, MD Wewers The Journal of Immunology 163 (4), 1755-1762, 1999 | 159 | 1999 |
Molecular basis for the action of a dietary flavonoid revealed by the comprehensive identification of apigenin human targets D Arango, K Morohashi, A Yilmaz, K Kuramochi, A Parihar, B Brahimaj, ... Proceedings of the National Academy of Sciences 110 (24), E2153-E2162, 2013 | 149 | 2013 |
IL-8-induced neutrophil chemotaxis is mediated by Janus kinase 3 (JAK3) KM Henkels, K Frondorf, ME Gonzalez-Mejia, AL Doseff, ... FEBS letters 585 (1), 159-166, 2011 | 140 | 2011 |
Keratinocyte growth factor induces Akt kinase activity and inhibits Fas-mediated apoptosis in A549 lung epithelial cells S Bao, Y Wang, P Sweeney, A Chaudhuri, AI Doseff, CB Marsh, DL Knoell American Journal of Physiology-Lung Cellular and Molecular Physiology 288 (1 …, 2005 | 120 | 2005 |
Regulation of monocyte apoptosis by the protein kinase Cδ-dependent phosphorylation of caspase-3 OH Voss, S Kim, MD Wewers, AI Doseff Journal of Biological Chemistry 280 (17), 17371-17379, 2005 | 116 | 2005 |
Regulation of monocytes and macrophages cell fate ME Gonzalez-Mejia, AI Doseff Front Biosci 14 (1), 2413-31, 2009 | 114 | 2009 |
Flavone deglycosylation increases their anti‐inflammatory activity and absorption G Hostetler, K Riedl, H Cardenas, M Diosa‐Toro, D Arango, S Schwartz, ... Molecular nutrition & food research 56 (4), 558-569, 2012 | 109 | 2012 |
Monocyte survival factors induce Akt activation and suppress caspase-3 A Goyal, Y Wang, MM Graham, AI Doseff, NY Bhatt, CB Marsh American journal of respiratory cell and molecular biology 26 (2), 224-230, 2002 | 106 | 2002 |
Flavonoids: New frontier for immuno-regulation and breast cancer control M Sudhakaran, S Sardesai, AI Doseff Antioxidants 8 (4), 103, 2019 | 95 | 2019 |
Dietary Apigenin Exerts Immune-Regulatory Activity in Vivo by Reducing NF-κB Activity, Halting Leukocyte Infiltration and Restoring Normal Metabolic Function H Cardenas, D Arango, C Nicholas, S Duarte, GJ Nuovo, W He, OH Voss, ... International journal of molecular sciences 17 (3), 323, 2016 | 93 | 2016 |
Apoptosis: the sculptor of development AI Doseff Stem cells and development 13 (5), 473-483, 2004 | 92 | 2004 |
Dietary flavonoids for immunoregulation and cancer: Food design for targeting disease JH Ahn-Jarvis, A Parihar, AI Doseff Antioxidants 8 (7), 202, 2019 | 88 | 2019 |