Diphenylprolinol silyl ethers as efficient organocatalysts for the asymmetric Michael reaction of aldehydes and nitroalkenes Y Hayashi, H Gotoh, T Hayashi, M Shoji Angewandte Chemie International Edition 44 (27), 4212-4215, 2005 | 1426 | 2005 |
Highly diastereo-and enantioselective direct aldol reactions in water Y Hayashi, T Sumiya, J Takahashi, H Gotoh, T Urushima, M Shoji Synfacts 2006 (03), 0274-0274, 2006 | 568 | 2006 |
Diphenylprolinol silyl ether as catalyst of an asymmetric, catalytic, and direct Michael reaction of nitroalkanes with α, β-unsaturated aldehydes H Gotoh, H Ishikawa, Y Hayashi Organic letters 9 (25), 5307-5309, 2007 | 286 | 2007 |
Cysteine-derived organocatalyst in a highly enantioselective intramolecular Michael reaction Y Hayashi, H Gotoh, T Tamura, H Yamaguchi, R Masui, M Shoji Journal of the American Chemical Society 127 (46), 16028-16029, 2005 | 252 | 2005 |
Asymmetric Diels–Alder reactions of α, β‐unsaturated aldehydes catalyzed by a Diarylprolinol Silyl ether salt in the presence of water Y Hayashi, S Samanta, H Gotoh, H Ishikawa Angewandte Chemie 120 (35), 6736-6739, 2008 | 190 | 2008 |
Diarylprolinol Silyl Ether as Catalyst of an exo-Selective, Enantioselective Diels−Alder Reaction H Gotoh, Y Hayashi Organic Letters 9 (15), 2859-2862, 2007 | 147 | 2007 |
Diphenylprolinol silyl ether catalysis in an asymmetric formal carbo [3+ 3] cycloaddition reaction via a domino Michael/Knoevenagel condensation Y Hayashi, M Toyoshima, H Gotoh, H Ishikawa Organic letters 11 (1), 45-48, 2009 | 127 | 2009 |
Diphenylprolinol silyl ether as a catalyst in an enantioselective, catalytic, formal aza [3+ 3] cycloaddition reaction for the formation of enantioenriched piperidines Y Hayashi, H Gotoh, R Masui, H Ishikawa Angewandte Chemie-International Edition 47 (21), 4012-4015, 2008 | 118 | 2008 |
Enantioselective ene reaction of cyclopentadiene and a, b-enals catalyzed by a diphenylprolinol silyl ether H Gotoh, R Masui, H Ogino, M Shoji, Y Hayashi ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH- 45 (41), 6853, 2006 | 116 | 2006 |
vol. 118, issue 6 Y Hayashi, T Sumiya, J Takahashi, H Gotoh, T Urushima, M Shoji Angew Chem, 972-975, 2006 | 109 | 2006 |
Organocatalytic, enantioselective intramolecular [6+ 2] cycloaddition reaction for the formation of tricyclopentanoids and insight on its mechanism from a computational study Y Hayashi, H Gotoh, M Honma, K Sankar, I Kumar, H Ishikawa, K Konno, ... Journal of the American Chemical Society 133 (50), 20175-20185, 2011 | 72 | 2011 |
10′-Fluorovinblastine and 10′-fluorovincristine: synthesis of a key series of modified Vinca alkaloids H Gotoh, KK Duncan, WM Robertson, DL Boger ACS medicinal chemistry letters 2 (12), 948-952, 2011 | 69 | 2011 |
Organocatalyst-mediated enantioselective intramolecular aldol reaction featuring the rare combination of aldehyde as nucleophile and ketone as electrophile Y Hayashi, H Sekizawa, J Yamaguchi, H Gotoh The Journal of Organic Chemistry 72 (17), 6493-6499, 2007 | 67 | 2007 |
A theoretical and experimental study of the effects of silyl substituents in enantioselective reactions catalyzed by diphenylprolinol silyl ether Y Hayashi, D Okamura, T Yamazaki, Y Ameda, H Gotoh, S Tsuzuki, ... Chemistry–A European Journal 20 (51), 17077-17088, 2014 | 62 | 2014 |
New insights into the mechanism and an expanded scope of the Fe (III)-mediated vinblastine coupling reaction H Gotoh, JE Sears, A Eschenmoser, DL Boger Journal of the American Chemical Society 134 (32), 13240-13243, 2012 | 62 | 2012 |
Diphenylprolinol silyl ether as a catalyst in an asymmetric, catalytic, and direct Michael reaction of nitroethanol with α, β-unsaturated aldehydes H Gotoh, D Okamura, H Ishikawa, Y Hayashi Organic Letters 11 (18), 4056-4059, 2009 | 62 | 2009 |
Two Reaction Mechanisms via Iminium Ion Intermediates: The Different Reactivities of Diphenylprolinol Silyl Ether and Trifluoromethyl‐Substituted Diarylprolinol Silyl Ether H Gotoh, T Uchimaru, Y Hayashi Chemistry–A European Journal 21 (35), 12337-12346, 2015 | 55 | 2015 |
Catharanthine C16 substituent effects on the biomimetic coupling with vindoline: preparation and evaluation of a key series of vinblastine analogues A Tam, H Gotoh, WM Robertson, DL Boger Bioorganic & medicinal chemistry letters 20 (22), 6408-6410, 2010 | 50 | 2010 |
First asymmetric total synthesis of synerazol, an antifungal antibiotic, and determination of its absolute stereochemistry Y Hayashi, M Shoji, T Mukaiyama, H Gotoh, S Yamaguchi, M Nakata, ... The Journal of Organic Chemistry 70 (14), 5643-5654, 2005 | 43 | 2005 |
Diphenylprolinol silyl ether as a catalyst in an asymmetric, catalytic and direct α-benzoyloxylation of aldehydes H Gotoh, Y Hayashi Chemical communications, 3083-3085, 2009 | 42 | 2009 |