Extracellular control of TGFβ signalling in vascular development and disease P Ten Dijke, HM Arthur Nature reviews Molecular cell biology 8 (11), 857-869, 2007 | 1047 | 2007 |
Endoglin promotes endothelial cell proliferation and TGF‐β/ALK1 signal transduction F Lebrin, MJ Goumans, L Jonker, RLC Carvalho, G Valdimarsdottir, ... The EMBO journal 23 (20), 4018-4028, 2004 | 867 | 2004 |
Endoglin, an ancillary TGFbeta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development DAG Arthur HM, Ure J, Smith AJ, Renforth G, Wilson DI, Torsney E, Charlton R ... Developmental Biology 217 (1), 42-53, 2000 | 617 | 2000 |
LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling X Wang, S Abraham, JAG McKenzie, N Jeffs, M Swire, VB Tripathi, ... Nature 499 (7458), 306-311, 2013 | 515 | 2013 |
The H9C2 cell line and primary neonatal cardiomyocyte cells show similar hypertrophic responses in vitro SJ Watkins, GM Borthwick, HM Arthur In Vitro Cellular & Developmental Biology-Animal 47, 125-131, 2011 | 445 | 2011 |
Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia F Lebrin, S Srun, K Raymond, S Martin, S Van Den Brink, C Freitas, ... Nature medicine 16 (4), 420-428, 2010 | 397 | 2010 |
Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence R Anderson, A Lagnado, D Maggiorani, A Walaszczyk, E Dookun, ... The EMBO journal 38 (5), e100492, 2019 | 391 | 2019 |
Pathogenesis of arteriovenous malformations in the absence of endoglin M Mahmoud, KR Allinson, Z Zhai, R Oakenfull, P Ghandi, RH Adams, ... Circulation research 106 (8), 1425-1433, 2010 | 291 | 2010 |
Defective paracrine signalling by TGFβ in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia RLC Carvalho, L Jonker, MJ Goumans, J Larsson, P Bouwman, ... Oxford University Press for The Company of Biologists Limited 131 (24), 6237 …, 2004 | 203 | 2004 |
Inducible expression of human endoglin during inflammation and wound healing in vivo E Torsney, R Charlton, D Parums, M Collis, HM Arthur Inflammation Research 51, 464-470, 2002 | 200 | 2002 |
Endoglin has a crucial role in blood cell–mediated vascular repair LW van Laake, S van den Driesche, S Post, A Feijen, MA Jansen, ... Circulation 114 (21), 2288-2297, 2006 | 195 | 2006 |
Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction A Walaszczyk, E Dookun, R Redgrave, S Tual‐Chalot, S Victorelli, ... Aging cell 18 (3), e12945, 2019 | 187 | 2019 |
Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling Y Jin, L Muhl, M Burmakin, Y Wang, AC Duchez, C Betsholtz, HM Arthur, ... Nature cell biology 19 (6), 639-652, 2017 | 183 | 2017 |
Therapeutic levels of aspirin and salicylate directly inhibit a model of angiogenesis through a Cox‐independent mechanism GM Borthwick, A Sarah Johnson, M Partington, J Burn, R Wilson, ... The FASEB journal 20 (12), 2009-2016, 2006 | 153 | 2006 |
Nonsynonymous variants in the SMAD6 gene predispose to congenital cardiovascular malformation HL Tan, E Glen, A Töpf, D Hall, JJ O'Sullivan, L Sneddon, C Wren, ... Human mutation 33 (4), 720-727, 2012 | 152 | 2012 |
Mouse model for hereditary hemorrhagic telangiectasia has a generalized vascular abnormality E Torsney, R Charlton, AG Diamond, J Burn, JV Soames, HM Arthur Circulation 107 (12), 1653-1657, 2003 | 150 | 2003 |
Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination C Anderberg, SI Cunha, Z Zhai, E Cortez, E Pardali, JR Johnson, ... Journal of Experimental Medicine 210 (3), 563-579, 2013 | 149 | 2013 |
Mouse models of hereditary hemorrhagic telangiectasia: recent advances and future challenges S Tual-Chalot, SP Oh, HM Arthur Frontiers in genetics 6, 25, 2015 | 142 | 2015 |
Novel brain arteriovenous malformation mouse models for type 1 hereditary hemorrhagic telangiectasia EJ Choi, W Chen, K Jun, HM Arthur, WL Young, H Su PloS one 9 (2), e88511, 2014 | 142 | 2014 |
Endothelial depletion of Acvrl1 in mice leads to arteriovenous malformations associated with reduced endoglin expression S Tual-Chalot, M Mahmoud, KR Allinson, RE Redgrave, Z Zhai, SP Oh, ... PloS one 9 (6), e98646, 2014 | 141 | 2014 |