Partial inhibition of Cdk1 in G2 phase overrides the SAC and decouples mitotic events RA McCloy, S Rogers, CE Caldon, T Lorca, A Castro, A Burgess Cell cycle 13 (9), 1400-1412, 2014 | 978 | 2014 |
Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance A Burgess, S Vigneron, E Brioudes, JC Labbé, T Lorca, A Castro Proceedings of the National Academy of Sciences 107 (28), 12564-12569, 2010 | 824 | 2010 |
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint A Abrieu, L Magnaghi-Jaulin, JA Kahana, M Peter, A Castro, S Vigneron, ... Cell 106 (1), 83-93, 2001 | 460 | 2001 |
The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A A Gharbi-Ayachi, JC Labbé, A Burgess, S Vigneron, JM Strub, E Brioudes, ... Science 330 (6011), 1673-1677, 2010 | 437 | 2010 |
The anaphase-promoting complex: a key factor in the regulation of cell cycle A Castro, C Bernis, S Vigneron, JC Labbe, T Lorca Oncogene 24 (3), 314-325, 2005 | 374 | 2005 |
Kinetochore localization of spindle checkpoint proteins: who controls whom? S Vigneron, S Prieto, C Bernis, JC Labbé, A Castro, T Lorca Molecular biology of the cell 15 (10), 4584-4596, 2004 | 272 | 2004 |
Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts T Lorca, A Castro, AM Martinez, S Vigneron, N Morin, S Sigrist, C Lehner, ... The EMBO journal, 1998 | 262 | 1998 |
Pathogenesis of arterial hypotension in cirrhotic rats with ascites: role of endogenous nitric oxide J Clària, W Jiménez, J Ros, M Asbert, A Castro, V Arroyo, F Rivera, ... Hepatology 15 (2), 343-349, 1992 | 238 | 1992 |
Impaired responsiveness to angiotensin II in experimental cirrhosis: role of nitric oxide A Castro, W Jiménez, J Clária, J Ros, JM Martínez, M Bosch, V Arroyo, ... Hepatology 18 (2), 367-372, 1993 | 220 | 1993 |
Greatwall maintains mitosis through regulation of PP2A S Vigneron, E Brioudes, A Burgess, JC Labbé, T Lorca, A Castro The EMBO journal 28 (18), 2786-2793, 2009 | 218 | 2009 |
APC/Fizzy‐Related targets Aurora‐A kinase for proteolysis A Castro, Y Arlot‐Bonnemains, S Vigneron, JC Labbé, C Prigent, T Lorca EMBO reports, 2002 | 197 | 2002 |
The APC is dispensable for first meiotic anaphase in Xenopus oocytes M Peter, A Castro, T Lorca, CL Peuch, L Magnaghi-Jaulin, M Dorée, ... Nature cell biology 3 (1), 83-87, 2001 | 161 | 2001 |
Interaction between Cyclin T1 and SCFSKP2 Targets CDK9 for Ubiquitination and Degradation by the Proteasome RE Kiernan, S Emiliani, K Nakayama, A Castro, JC Labbé, T Lorca, ... Molecular and cellular biology 21 (23), 7956-7970, 2001 | 124 | 2001 |
The D‐Box‐activating domain (DAD) is a new proteolysis signal that stimulates the silent D‐Box sequence of Aurora‐A A Castro, S Vigneron, C Bernis, JC Labbé, C Prigent, T Lorca EMBO reports, 2002 | 122 | 2002 |
Greatwall is essential to prevent mitotic collapse after nuclear envelope breakdown in mammals. MM Alvarez-Fernandez M, Sanchez-Martinez R, Sanz-Castillo B, Gan PP, Sanz ... PNAS 110 (43), 17374-17379, 2013 | 118* | 2013 |
Cyclin A-cdk1-dependent phosphorylation of Bora is the triggering factor promoting mitotic entry S Vigneron, L Sundermann, JC Labbé, L Pintard, O Radulescu, A Castro, ... Developmental cell 45 (5), 637-650. e7, 2018 | 98 | 2018 |
Xkid is degraded in a D-box, KEN-box, and A-box-independent pathway A Castro, S Vigneron, C Bernis, JC Labbé, T Lorca Molecular and cellular biology 23 (12), 4126-4138, 2003 | 92 | 2003 |
Constant regulation of both the MPF amplification loop and the Greatwall-PP2A pathway is required for metaphase II arrest and correct entry into the first embryonic cell cycle T Lorca, C Bernis, S Vigneron, A Burgess, E Brioudes, JC Labbé, ... Journal of cell science 123 (13), 2281-2291, 2010 | 89 | 2010 |
Effect of V1-vasopressin receptor blockade on arterial pressure in conscious rats with cirrhosis and ascites J Claria, W Jiménez, V Arroyo, G La Villa, C López, M Asbert, A Castro, ... Gastroenterology 100 (2), 494-501, 1991 | 88 | 1991 |
Cyclin B/cdc2 Induces c-Mos Stability by Direct Phosphorylation in Xenopus Oocytes A Castro, M Peter, L Magnaghi-Jaulin, S Vigneron, S Galas, T Lorca, ... Molecular biology of the cell 12 (9), 2660-2671, 2001 | 85 | 2001 |