Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent AO Kamphorst, A Wieland, T Nasti, S Yang, R Zhang, DL Barber, ... Science 355 (6332), 1423-1427, 2017 | 989 | 2017 |
Proliferation of PD-1+ CD8 T cells in peripheral blood after PD-1–targeted therapy in lung cancer patients AO Kamphorst, RN Pillai, S Yang, TH Nasti, RS Akondy, A Wieland, ... Proceedings of the National Academy of Sciences 114 (19), 4993-4998, 2017 | 812 | 2017 |
Proliferating transitory T cells with an effector-like transcriptional signature emerge from PD-1+ stem-like CD8+ T cells during chronic infection WH Hudson, J Gensheimer, M Hashimoto, A Wieland, RM Valanparambil, ... Immunity 51 (6), 1043-1058. e4, 2019 | 547 | 2019 |
Effector CD8 T cells dedifferentiate into long-lived memory cells B Youngblood, JS Hale, HT Kissick, E Ahn, X Xu, A Wieland, K Araki, ... Nature 552 (7685), 404-409, 2017 | 511 | 2017 |
Metabolic phenotypes of response to vaccination in humans S Li, NL Sullivan, N Rouphael, T Yu, S Banton, MS Maddur, ... Cell 169 (5), 862-877. e17, 2017 | 269 | 2017 |
Functional HPV-specific PD-1+ stem-like CD8 T cells in head and neck cancer CS Eberhardt, HT Kissick, MR Patel, MA Cardenas, N Prokhnevska, ... Nature 597 (7875), 279-284, 2021 | 247 | 2021 |
Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection P Penaloza-MacMaster, AO Kamphorst, A Wieland, K Araki, SS Iyer, ... Journal of Experimental Medicine 211 (9), 1905-1918, 2014 | 237 | 2014 |
PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program M Hashimoto, K Araki, MA Cardenas, P Li, RR Jadhav, HT Kissick, ... Nature 610 (7930), 173-181, 2022 | 192 | 2022 |
Defining HPV-specific B cell responses in patients with head and neck cancer A Wieland, MR Patel, MA Cardenas, CS Eberhardt, WH Hudson, ... Nature 597 (7875), 274-278, 2021 | 180 | 2021 |
Temporal expression of microRNA cluster miR-17-92 regulates effector and memory CD8+ T-cell differentiation T Wu, A Wieland, K Araki, CW Davis, L Ye, JS Hale, R Ahmed Proceedings of the National Academy of Sciences 109 (25), 9965-9970, 2012 | 155 | 2012 |
Tumor-draining lymph node is important for a robust abscopal effect stimulated by radiotherapy ZS Buchwald, TH Nasti, J Lee, CS Eberhardt, A Wieland, SJ Im, D Lawson, ... Journal for immunotherapy of cancer 8 (2), 2020 | 118 | 2020 |
Comparative Analysis of Simian Immunodeficiency Virus Gag-Specific Effector and Memory CD8+ T Cells Induced by Different Adenovirus Vectors WG Tan, HT Jin, EE West, P Penaloza-MacMaster, A Wieland, MJ Zilliox, ... Journal of virology 87 (3), 1359-1372, 2013 | 102 | 2013 |
Antibody effector functions mediated by Fcγ-receptors are compromised during persistent viral infection A Wieland, R Shashidharamurthy, AO Kamphorst, JH Han, RD Aubert, ... Immunity 42 (2), 367-378, 2015 | 73 | 2015 |
Distinct phenotypic states and spatial distribution of CD8+ T cell clonotypes in human brain metastases LJ Sudmeier, KB Hoang, EK Nduom, A Wieland, SG Neill, ... Cell Reports Medicine 3 (5), 2022 | 63 | 2022 |
T cell receptor sequencing of activated CD8 T cells in the blood identifies tumor-infiltrating clones that expand after PD-1 therapy and radiation in a melanoma patient A Wieland, AO Kamphorst, NV Adsay, JJ Masor, J Sarmiento, TH Nasti, ... Cancer Immunology, Immunotherapy 67, 1767-1776, 2018 | 63 | 2018 |
Antigen density dictates immune responsiveness following red blood cell transfusion CM Arthur, SR Patel, NH Smith, A Bennett, NA Kamili, A Mener, ... The Journal of Immunology 198 (7), 2671-2680, 2017 | 60 | 2017 |
Elimination of immunodominant epitopes from multispecific DNA-based vaccines allows induction of CD8 T cells that have a striking antiviral potential P Riedl, A Wieland, K Lamberth, S Buus, F Lemonnier, K Reifenberg, ... The Journal of Immunology 183 (1), 370-380, 2009 | 49 | 2009 |
Broadly reactive human CD8 T cells that recognize an epitope conserved between VZV, HSV and EBV C Chiu, M McCausland, J Sidney, FM Duh, N Rouphael, A Mehta, ... PLoS pathogens 10 (3), e1004008, 2014 | 46 | 2014 |
Complement serves as a switch between CD4+ T cell–independent and–dependent RBC antibody responses A Mener, SR Patel, CM Arthur, S Chonat, A Wieland, M Santhanakrishnan, ... JCI insight 3 (22), 2018 | 45 | 2018 |
mTOR regulates T cell exhaustion and PD-1–targeted immunotherapy response during chronic viral infection S Ando, CM Perkins, Y Sajiki, C Chastain, RM Valanparambil, A Wieland, ... The Journal of Clinical Investigation 133 (2), 2023 | 39 | 2023 |