Targeted protein degradation: current and future challenges A Hanzl, GE Winter Current opinion in chemical biology 56, 35-41, 2020 | 105 | 2020 |
Selective Mediator dependence of cell-type-specifying transcription MG Jaeger, B Schwalb, SD Mackowiak, T Velychko, A Hanzl, H Imrichova, ... Nature genetics 52 (7), 719-727, 2020 | 101 | 2020 |
Plasticity of the Cullin-RING ligase repertoire shapes sensitivity to ligand-induced protein degradation C Mayor-Ruiz, MG Jaeger, S Bauer, M Brand, C Sin, A Hanzl, AC Mueller, ... Molecular cell 75 (4), 849-858. e8, 2019 | 92 | 2019 |
Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders A Hanzl, R Casement, H Imrichova, SJ Hughes, E Barone, A Testa, ... Nature chemical biology 19 (3), 323-333, 2023 | 56 | 2023 |
E3-specific degrader discovery by dynamic tracing of substrate receptor abundance A Hanzl, E Barone, S Bauer, H Yue, RP Nowak, E Hahn, EV Pankevich, ... Journal of the American Chemical Society 145 (2), 1176-1184, 2023 | 24 | 2023 |
Genome-scale CRISPR screens are efficient in non-homologous end-joining deficient cells J Ferreira da Silva, S Salic, M Wiedner, P Datlinger, P Essletzbichler, ... Scientific Reports 9 (1), 15751, 2019 | 20 | 2019 |
Charting functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders A Hanzl, R Casement, H Imrichova, SJ Hughes, E Barone, A Testa, ... BioRxiv, 2022.04. 14.488316, 2022 | 4 | 2022 |
Neue Krebstherapien: Resistenzen vorbeugen und überwinden A Hanzl TumorDiagn u Ther 44, 2023 | | 2023 |