| Large-scale public data reuse to model immunotherapy response and resistance PJXSL Jingxin Fu, Karen Li, Wubing Zhang, Changxin Wan, Jing Zhang Genome Medicine 12 (1), 1-8, 2020 | 680 | 2020 |
| Integrative analysis of pooled CRISPR genetic screens using MAGeCKFlute B Wang, M Wang, W Zhang, T Xiao, CH Chen, A Wu, F Wu, N Traugh, ... Nature protocols 14 (3), 756-780, 2019 | 316 | 2019 |
| Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis ND Mathewson, O Ashenberg, I Tirosh, S Gritsch, EM Perez, S Marx, ... Cell 184 (5), 1281-1298. e26, 2021 | 281 | 2021 |
| Therapeutically increasing MHC-I expression potentiates immune checkpoint blockade SS Gu, W Zhang, X Wang, P Jiang, N Traugh, Z Li, C Meyer, B Stewig, ... Cancer discovery 11 (6), 1524-1541, 2021 | 135 | 2021 |
| TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response Z Zeng, CJ Wong, L Yang, N Ouardaoui, D Li, W Zhang, S Gu, Y Zhang, ... Nucleic acids research 50 (D1), D1391-D1397, 2022 | 67 | 2022 |
| High-resolution alignment of single-cell and spatial transcriptomes with CytoSPACE MR Vahid, EL Brown, CB Steen, W Zhang, HS Jeon, M Kang, AJ Gentles, ... Nature biotechnology 41 (11), 1543-1548, 2023 | 66 | 2023 |
| ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells X Liu, T Liu, Y Shang, P Dai, W Zhang, BJ Lee, M Huang, D Yang, Q Wu, ... Cell research 30 (9), 732-744, 2020 | 53 | 2020 |
| Systematic characterization of mutations altering protein degradation in human cancers C Tokheim, X Wang, RT Timms, B Zhang, EL Mena, B Wang, C Chen, ... Molecular cell 81 (6), 1292-1308. e11, 2021 | 50 | 2021 |
| Inhibition of MAN2A1 Enhances the Immune Response to Anti–PD-L1 in Human Tumors S Shi, S Gu, T Han, W Zhang, L Huang, Z Li, D Pan, J Fu, J Ge, M Brown, ... Clinical Cancer Research 26 (22), 5990-6002, 2020 | 38 | 2020 |
| Pan-cancer proteogenomics connects oncogenic drivers to functional states Y Li, E Porta-Pardo, C Tokheim, MH Bailey, TM Yaron, V Stathias, ... Cell 186 (18), 3921-3944. e25, 2023 | 31 | 2023 |
| Machine learning modeling of protein-intrinsic features predicts tractability of targeted protein degradation W Zhang, SS Roy Burman, J Chen, KA Donovan, Y Cao, C Shu, B Zhang, ... Genomics, Proteomics and Bioinformatics 20 (5), 882-898, 2022 | 22 | 2022 |
| CRISP-view: a database of functional genetic screens spanning multiple phenotypes Y Cui, X Cheng, Q Chen, B Song, A Chiu, Y Gao, T Dawson, L Chao, ... Nucleic acids research 49 (D1), D848-D854, 2021 | 20 | 2021 |
| Clonal tracing reveals diverse patterns of response to immune checkpoint blockade SS Gu, X Wang, X Hu, P Jiang, Z Li, N Traugh, X Bu, Q Tang, C Wang, ... Genome biology 21, 1-28, 2020 | 18 | 2020 |
| Discovery of targets for immune–metabolic antitumor drugs identifies estrogen-related receptor alpha A Sahu, X Wang, P Munson, JPG Klomp, X Wang, SS Gu, Y Han, G Qian, ... Cancer discovery 13 (3), 672-701, 2023 | 16 | 2023 |
| Machine learning on syngeneic mouse tumor profiles to model clinical immunotherapy response Z Zeng, SS Gu, CJ Wong, L Yang, N Ouardaoui, D Li, W Zhang, M Brown, ... Science Advances 8 (41), eabm8564, 2022 | 11 | 2022 |
| Hippo signaling pathway regulates cancer cell–intrinsic MHC-II expression Z Zeng, SS Gu, N Ouardaoui, C Tymm, L Yang, CJ Wong, D Li, W Zhang, ... Cancer Immunology Research 10 (12), 1559-1569, 2022 | 10 | 2022 |
| MetaTiME integrates single-cell gene expression to characterize the meta-components of the tumor immune microenvironment Y Zhang, G Xiang, AY Jiang, A Lynch, Z Zeng, C Wang, W Zhang, J Fan, ... Nature communications 14 (1), 2634, 2023 | 9 | 2023 |
| Mapping single-cell developmental potential in health and disease with interpretable deep learning M Kang, JJA Armenteros, GS Gulati, R Gleyzer, S Avagyan, EL Brown, ... bioRxiv, 2024.03. 19.585637, 2024 | 6 | 2024 |
| CD4 T cells and toxicity from immune checkpoint blockade N Earland, W Zhang, A Usmani, A Nene, A Bacchiocchi, DY Chen, ... Immunological Reviews 318 (1), 96-109, 2023 | 6 | 2023 |
| A community challenge to predict clinical outcomes after immune checkpoint blockade in non-small cell lung cancer M Mason, Ó Lapuente-Santana, AS Halkola, W Wang, R Mall, X Xiao, ... Journal of translational medicine 22 (1), 190, 2024 | 5 | 2024 |
Xiaole Shirley LiuCEO, GV20 Therapeutics在 ds.dfci.harvard.edu 的电子邮件经过验证
