| SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans TK Blackwell, MJ Steinbaugh, JM Hourihan, CY Ewald, M Isik Free Radical Biology and Medicine 88, 290-301, 2015 | 553 | 2015 |
| Post-transcriptional regulation of de novo lipogenesis by mTORC1-S6K1-SRPK2 signaling G Lee, Y Zheng, S Cho, C Jang, C England, JM Dempsey, Y Yu, X Liu, ... Cell 171 (7), 1545-1558. e18, 2017 | 203 | 2017 |
| Dietary Restriction Extends Lifespan through Metabolic Regulation of Innate Immunity Z Wu, M Isik, N Moroz, MJ Steinbaugh, P Zhang, TK Blackwell Cell Metabolism, 2019 | 150 | 2019 |
| Expression patterns of intronic microRNAs in Caenorhabditis elegans M Isik, H Korswagen, E Berezikov | 96 | 2010 |
| MicroRNA mir-34 provides robustness to environmental stress response via the DAF-16 network in C. elegans M Isik, E Blackwell, Keith T., Berezikov Nature, Scientific Reports, 2016 | 58 | 2016 |
| GLTSCR2/PICT1 links mitochondrial stress and Myc signaling JC Yoon, AJY Ling, M Isik, DYD Lee, MJ Steinbaugh, LM Sack, ... Proceedings of the National Academy of Sciences 111 (10), 3781-3786, 2014 | 19 | 2014 |
| Biolistic Transformation of Caenorhabditis elegans M Isik, E Berezikov Biolistic DNA Delivery: Methods and Protocols, 77-86, 2013 | 13 | 2013 |
| CALITAS: A CRISPR-Cas-aware ALigner for In silico off-TArget Search T Fennell, D Zhang, M Isik, T Wang, G Gotta, CJ Wilson, E Marco The CRISPR Journal 4 (2), 264-274, 2021 | 12 | 2021 |
| Defective brown adipose tissue thermogenesis and impaired glucose metabolism in mice lacking Letmd1 KM Choi, JH Kim, X Kong, M Isik, J Zhang, HW Lim, JC Yoon Cell Reports 37 (11), 2021 | 11 | 2021 |
| Dietary restriction extends lifespan through metabolic regulation of innate immunity Z Wu, M Isik, N Moroz, MJ Steinbaugh, P Zhang, TK Blackwell Cell metabolism 33 (10), 2090, 2021 | 8 | 2021 |
| Expression Pattern Analysis of MicroRNAs in Caenorhabditis elegans M Isik, E Berezikov MicroRNA Protocols, 129-141, 2013 | 8 | 2013 |
| ERK signaling licenses SKN-1A/NRF1 for proteasome production and proteasomal stress resistance P Zhang, HY Qu, Z Wu, H Na, J Hourihan, F Zhang, F Zhu, M Isik, ... bioRxiv, 2021.01. 04.425272, 2021 | 6 | 2021 |
| PS1518 Genome Editing Of HBG1/2 Promoter Leads to Robust Hbf Induction In Vivo, While Editing of BCL11A Erythroid Enhancer Results In Erythroid Defects J Heath, E de Dreuzy, M Sanchez, S Haskett, T Wang, P Sousa, G Gotta, ... HemaSphere 3 (S1), 699-700, 2019 | 6 | 2019 |
| Comparative studies reveal robust HbF induction by editing of HBG1/2 promoters or BCL11A erythroid-enhancer in human CD34+ Cells but that BCL11A erythroid-enhancer editing is … KH Chang, M Sanchez, J Heath, E deDreuzy, S Haskett, A Vogelaar, ... Blood 132 (Supplement 1), 409-409, 2018 | 6 | 2018 |
| P1429: MULTIPLEX DELETION OF MYELOID ANTIGENS CD33 AND CLL-1 BY CRISPR/CAS9 IN HUMAN HEMATOPOIETIC STEM CELLS HIGHLIGHTS THE POTENTIAL OF NEXT-GENERATION TRANSPLANTS FOR AML … J Xavier-Ferrucio, C Luo, G Angelini, S Krishnamurthy, N Patel, M Pettiglio, ... HemaSphere 6, 1312-1313, 2022 | 2 | 2022 |
| Knock out of CD123 or CLL-1 By CRISPR-Cas9 Editing from Human Hematopoietic Stem Cell Transplants Provide New Possibilities for Increasing Therapeutic Index and Safety for AML … C Luo, G Angelini, S Krishnamurthy, J Lisle, M Isik, A Ghdossi, ... Blood 138, 3818, 2021 | 1 | 2021 |
| Rigorous Assessment of Off-Target Editing by CRISPR/Cas9 in VOR33, an Engineered Hematopoietic Stem Cell Transplant for the Treatment of Acute Myeloid Leukemia D Hazelbaker, M Isik, A Ghodssi, M Ung, A Halfond, S Wang, K Cummins, ... Molecular Therapy 29 (4), 408-409, 2021 | 1 | 2021 |
| VOR33: A Clinic-Ready CRISPR/Cas9 Engineered Hematopoietic Stem Cell Transplant for the Treatment of Acute Myeloid Leukemia J Lydeard, M Lin, C Luo, S Wang, A Halfond, MB Jones, J Scherer, ... Molecular Therapy, 2021 | 1 | 2021 |
| CRISPR-Cas9-mediated genome editing delivered by a single AAV9 vector inhibits HSV-1 reactivation in a latent rabbit keratitis model N Amrani, K Luk, P Singh, M Shipley, M Isik, M Donadoni, A Bellizzi, ... Molecular Therapy Methods & Clinical Development, 2024 | | 2024 |
| Multiplex Engineering of Human CD34+ HSPCs Enables Dual Gene Knock-out While Maintaining High Engraftment Potential and Safety N Patel, M Pettiglio, C Cummins, J Pimentel, A Kapuria, A Ghodssi, M Isik, ... Blood 138, 2939, 2021 | | 2021 |
