BCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Ph chromosome-positive leukemia MS Zabriskie, CA Eide, SK Tantravahi, NA Vellore, J Estrada, FE Nicolini, ... Cancer cell 26 (3), 428-442, 2014 | 349 | 2014 |
Wordom: a user‐friendly program for the analysis of molecular structures, trajectories, and free energy surfaces M Seeber, A Felline, F Raimondi, S Muff, R Friedman, F Rao, A Caflisch, ... Journal of computational chemistry 32 (6), 1183-1194, 2011 | 264 | 2011 |
Membrane protein structure, function, and dynamics: a perspective from experiments and theory Z Cournia, TW Allen, I Andricioaei, B Antonny, D Baum, G Brannigan, ... The Journal of membrane biology 248, 611-640, 2015 | 234 | 2015 |
Amyloid aggregation on lipid bilayers and its impact on membrane permeability R Friedman, R Pellarin, A Caflisch Journal of molecular biology 387 (2), 407-415, 2009 | 161 | 2009 |
Terahertz radiation induces non-thermal structural changes associated with Fröhlich condensation in a protein crystal IV Lundholm, H Rodilla, WY Wahlgren, A Duelli, G Bourenkov, J Vukusic, ... Structural Dynamics 2 (5), 2015 | 113 | 2015 |
Drug resistance in cancer: molecular evolution and compensatory proliferation R Friedman Oncotarget 7 (11), 11746, 2016 | 85 | 2016 |
Molecular modelling and simulations in cancer research R Friedman, K Boye, K Flatmark Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1836 (1), 1-14, 2013 | 76 | 2013 |
Discovery of plasmepsin inhibitors by fragment‐based docking and consensus scoring R Friedman, A Caflisch ChemMedChem 4 (8), 1317-1326, 2009 | 76 | 2009 |
Molecular dynamics of a protein surface: ion-residues interactions R Friedman, E Nachliel, M Gutman Biophysical journal 89 (2), 768-781, 2005 | 73 | 2005 |
Fatty acid binding proteins: same structure but different binding mechanisms? Molecular dynamics simulations of intestinal fatty acid binding protein R Friedman, E Nachliel, M Gutman Biophysical journal 90 (5), 1535-1545, 2006 | 57 | 2006 |
Aggregation of amyloids in a cellular context: modelling and experiment R Friedman Biochemical Journal 438 (3), 415-426, 2011 | 56 | 2011 |
Dilution of whisky–the molecular perspective BCG Karlsson, R Friedman Scientific reports 7 (1), 6489, 2017 | 54 | 2017 |
Molecular dynamics simulations of palmitate entry into the hydrophobic pocket of the fatty acid binding protein Y Tsfadia, R Friedman, J Kadmon, A Selzer, E Nachliel, M Gutman Febs Letters 581 (6), 1243-1247, 2007 | 50 | 2007 |
A molecular dynamics study and free energy analysis of complexes between the Mlc1p protein and two IQ motif peptides A Ganoth, R Friedman, E Nachliel, M Gutman Biophysical journal 91 (7), 2436-2450, 2006 | 48 | 2006 |
Ions and the protein surface revisited: extensive molecular dynamics simulations and analysis of protein structures in alkali-chloride solutions R Friedman The Journal of Physical Chemistry B 115 (29), 9213-9223, 2011 | 44 | 2011 |
Molecular Dynamics Simulations of the Adipocyte Lipid Binding Protein Reveal a Novel Entry Site for the Ligand, R Friedman, E Nachliel, M Gutman Biochemistry 44 (11), 4275-4283, 2005 | 41 | 2005 |
Membrane–ion interactions R Friedman The Journal of membrane biology 251 (3), 453-460, 2018 | 40 | 2018 |
Understanding conformational dynamics of complex lipid mixtures relevant to biology R Friedman, S Khalid, C Aponte-Santamaría, E Arutyunova, M Becker, ... The Journal of membrane biology 251, 609-631, 2018 | 38 | 2018 |
The protonation state of the catalytic aspartates in plasmepsin II R Friedman, A Caflisch FEBS letters 581 (21), 4120-4124, 2007 | 38 | 2007 |
A molecular dynamics study of the effect of Ca2+ removal on calmodulin structure R Friedman, E Nachliel, M Gutman Biophysical journal 90 (11), 3842-3850, 2006 | 38 | 2006 |