| 2-Amino-3-substituted-6-[(E)-1-phenyl-2-(N-methylcarbamoyl)vinyl]imidazo[1,2-a]pyridines as a Novel Class of Inhibitors of Human Rhinovirus: Stereospecific … C Hamdouchi, J de Blas, M del Prado, J Gruber, BA Heinz, L Vance Journal of medicinal chemistry 42 (1), 50-59, 1999 | 332 | 1999 |
| 3-(4-Chloro-2-morpholin-4-yl-thiazol-5-yl)-8-(1-ethylpropyl)-2, 6-dimethyl-imidazo [1, 2-b] pyridazine: a novel brain-penetrant, orally available corticotropin-releasing factor … DR Gehlert, A Cippitelli, A Thorsell, AD Lê, PA Hipskind, C Hamdouchi, ... Journal of Neuroscience 27 (10), 2718-2726, 2007 | 264 | 2007 |
| Delayed functional expression of neuronal chemokine receptors following focal nerve demyelination in the rat: a mechanism for the development of chronic sensitization of … S Bhangoo, D Ren, RJ Miller, KJ Henry, J Lineswala, C Hamdouchi, B Li, ... Molecular pain 3, 1744-8069-3-38, 2007 | 204 | 2007 |
| Structure-based design of a new class of highly selective aminoimidazo[1,2-a]pyridine-based inhibitors of cyclin dependent kinases C Hamdouchi, B Zhong, J Mendoza, E Collins, C Jaramillo, JE De Diego, ... Bioorganic & medicinal chemistry letters 15 (7), 1943-1947, 2005 | 108 | 2005 |
| Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond R Ciccocioppo, DR Gehlert, A Ryabinin, S Kaur, A Cippitelli, A Thorsell, ... Alcohol 43 (7), 491-498, 2009 | 85 | 2009 |
| A new approach to the synthesis of 2-aminoimidazo[1,2-a]pyridine derivatives through microwave-assisted N-alkylation of 2-halopyridines JA Vega, JJ Vaquero, J Alvarez-Builla, J Ezquerra, C Hamdouchi Tetrahedron 55 (8), 2317-2326, 1999 | 81 | 1999 |
| On the reaction of chiral sulfinimines with sulfur ylides: a novel route to the asymmetric aziridination JLG Ruano, I Fernández, C Hamdouchi Tetrahedron letters 36 (2), 295-298, 1995 | 80 | 1995 |
| Structural basis for GPR40 allosteric agonism and incretin stimulation JD Ho, B Chau, L Rodgers, F Lu, KL Wilbur, KA Otto, Y Chen, M Song, ... Nature Communications 9 (1), 1645, 2018 | 68 | 2018 |
| Imidazo[1,2-b]pyridazines, Novel Nucleus with Potent and Broad Spectrum Activity against Human Picornaviruses: Design, Synthesis, and Biological Evaluation C Hamdouchi, C Sanchez-Martinez, J Gruber, M Del Prado, J Lopez, ... Journal of medicinal chemistry 46 (20), 4333-4341, 2003 | 65 | 2003 |
| The discovery, preclinical, and early clinical development of potent and selective GPR40 agonists for the treatment of type 2 diabetes mellitus (LY2881835, LY2922083, and … C Hamdouchi, SD Kahl, A Patel Lewis, GR Cardona, RW Zink, K Chen, ... Journal of Medicinal Chemistry 59 (24), 10891-10916, 2016 | 56 | 2016 |
| Aminoimidazo [1, 2-a] pyridines as a new structural class of cyclin-dependent kinase inhibitors. Part 1: Design, synthesis, and biological evaluation C Jaramillo, JE de Diego, C Hamdouchi, E Collins, H Keyser, ... Bioorganic & medicinal chemistry letters 14 (24), 6095-6099, 2004 | 53 | 2004 |
| Short synthesis and anti-rhinoviral activity of imidazo [1, 2-a] pyridines: the effect of acyl groups at 3-position C Hamdouchi, J Ezquerra, JA Vega, JJ Vaquero, J Alvarez-Builla, ... Bioorganic & medicinal chemistry letters 9 (10), 1391-1394, 1999 | 50 | 1999 |
| Surface nature of Grignard reagent formation. Chiral 1-methylspiro [2.5] octylmagnesium bromide C Hamdouchi, M Topolski, V Goedken, HM Walborsky The Journal of Organic Chemistry 58 (11), 3148-3155, 1993 | 49 | 1993 |
| The discovery of a new structural class of cyclin-dependent kinase inhibitors, aminoimidazo[1,2-a]pyridines C Hamdouchi, H Keyser, E Collins, C Jaramillo, JE De Diego, ... Molecular cancer therapeutics 3 (1), 1-9, 2004 | 48 | 2004 |
| Chemoselective arylsulfenylation of 2-aminoimidazol [1, 2-a] pyridines by phenyliodine (III) bis (trifluoroacetate)(PIFA) C Hamdouchi, C Sanchez, J Ezquerra Synthesis 1998 (06), 867-872, 1998 | 44 | 1998 |
| (S, S)-bis-p-tolylsulfinylmethane and carbonyl compounds: reactivity and asymmetric induction G Solladié, F Colobert, P Ruiz, C Hamdouchi, MC Carreno, L José, ... Tetrahedron letters 32 (30), 3695-3698, 1991 | 42 | 1991 |
| Imidazopyridazine compounds HJ Barbosa, EA Collins, C Hamdouchi, EJ Hembre, PA Hipskind, ... US Patent 7,612,067, 2009 | 40 | 2009 |
| A novel application of the Ullmann coupling reaction for the alkylsulfenylation of 2-amino-imidazo[1,2-a]pyridine C Hamdouchi, J de Blas, J Ezquerra Tetrahedron 55 (2), 541-548, 1999 | 36 | 1999 |
| A new approach to the asymmetric cyclopropanation via a chiral sulfinyl group C Hamdouchi Tetrahedron letters 33 (13), 1701-1704, 1992 | 35 | 1992 |
| The nature of electron transfer from metal surfaces to the carbon-halogen bond HM Walborsky, C Hamdouchi Journal of the American Chemical Society 115 (14), 6406-6408, 1993 | 34 | 1993 |
