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Laeeq Malik
Laeeq Malik
Staff Specialist in Medical Oncology at Canberra Hospital and Lecturer Australian National
在 act.gov.au 的电子邮件经过验证
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引用次数
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年份
LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer
T Boulding, RD McCuaig, A Tan, K Hardy, F Wu, J Dunn, M Kalimutho, ...
Scientific reports 8 (1), 73, 2018
1422018
Pharmacokinetics in Drug Development: Advances and Applications, Volume 3
PL Bonate, DR Howard
Springer Science & Business Media, 2011
81*2011
Final results from the PERUSE study of first-line pertuzumab plus trastuzumab plus a taxane for HER2-positive locally recurrent or metastatic breast cancer, with a …
D Miles, E Ciruelos, A Schneeweiss, F Puglisi, T Peretz-Yablonski, ...
Annals of Oncology 32 (10), 1245-1255, 2021
512021
Phase I study of intravenously administered ATI-1123, a liposomal docetaxel formulation in patients with advanced solid tumors
D Mahalingam, JJ Nemunaitis, L Malik, J Sarantopoulos, S Weitman, ...
Cancer chemotherapy and pharmacology 74, 1241-1250, 2014
492014
Targeting nuclear LSD1 to reprogram cancer cells and reinvigorate exhausted T cells via a novel LSD1-EOMES switch
WJ Tu, RD McCuaig, AHY Tan, K Hardy, N Seddiki, S Ali, JE Dahlstrom, ...
Frontiers in Immunology 11, 1228, 2020
442020
Role of immunotherapy in bladder cancer: past, present and future
SR Butt, L Malik
Cancer Chemotherapy and Pharmacology 81, 629-645, 2018
442018
Phase II study evaluating the efficacy, safety, and pharmacodynamic correlative study of dual antiangiogenic inhibition using bevacizumab in combination with sorafenib in …
D Mahalingam, L Malik, M Beeram, J Rodon, K Sankhala, A Mita, ...
Cancer chemotherapy and pharmacology 74, 77-84, 2014
332014
Optimizing poly (ADP‐ribose) polymerase inhibition through combined epigenetic and immunotherapy
T Prasanna, F Wu, KK Khanna, D Yip, L Malik, JE Dahlstrom, S Rao
Cancer Science 109 (11), 3383-3392, 2018
312018
Relationship of pharmacokinetics (PK), toxicity, and initial evidence of clinical activity with IMGN853, a folate receptor alpha (FRa) targeting antibody drug conjugate in …
KN Moore, J Ponte, P LoRusso, MJ Birrer, TM Bauer, H Borghaei, ...
Journal of Clinical Oncology 32 (15_suppl), 5571-5571, 2014
262014
Eligibility criteria for phase I clinical trials: tight vs loose?
L Malik, D Lu
Cancer Chemotherapy and Pharmacology 83, 999-1002, 2019
212019
Predicting success in regulatory approval from Phase I results
L Malik, A Mejia, H Parsons, B Ehler, D Mahalingam, A Brenner, ...
Cancer chemotherapy and pharmacology 74, 1099-1103, 2014
192014
Nuclear-biased DUSP6 expression is associated with cancer spreading including brain metastasis in triple-negative breast cancer
F Wu, RD McCuaig, CR Sutton, AHY Tan, Y Jeelall, EG Bean, J Dai, ...
International journal of molecular sciences 20 (12), 3080, 2019
182019
How well informed is the informed consent for cancer clinical trials?
L Malik, J Kuo, D Yip, A Mejia
Clinical Trials 11 (6), 686-688, 2014
182014
First-in-human phase 1 dose-escalation study of AV-203, a monoclonal antibody against ERBB3, in patients with metastatic or advanced solid tumors.
J Sarantopoulos, MS Gordon, RD Harvey, KK Sankhala, L Malik, ...
Journal of Clinical Oncology 32 (15_suppl), 11113-11113, 2014
172014
Increasing complexity in oncology phase I clinical trials
L Malik, D Lu
Investigational new drugs 37, 519-523, 2019
152019
Advanced cancer patients’ understanding and perceptions of phase I clinical trials
J Pawlowski, L Malik, D Mahalingam
Cancer Investigation 33 (10), 490-495, 2015
122015
Informed consent for phase I oncology trials: form, substance and signature
L Malik, A Mejia
Journal of Clinical Medicine Research 6 (3), 205, 2014
112014
Addition of endocrine therapy to dual anti-HER2 targeted therapy in initial treatment of HER2+/HR+ metastatic breast cancer
M Loft, SW Lok, R De Boer, L Malik, S Greenberg, B Yeo, A Anton, ...
Breast Cancer Research and Treatment 198 (1), 67-74, 2023
92023
Simple and effective bacterial-based intratumoral cancer immunotherapy
CSE Carroll, ER Andrew, L Malik, KF Elliott, M Brennan, J Meyer, A Hintze, ...
Journal for immunotherapy of cancer 9 (9), 2021
92021
Selective Targeting of Protein Kinase C (PKC)-θ Nuclear Translocation Reduces Mesenchymal Gene Signatures and Reinvigorates Dysfunctional CD8+ T Cells in …
J Dunn, RD McCuaig, AHY Tan, WJ Tu, F Wu, KM Wagstaff, A Zafar, S Ali, ...
Cancers 14 (6), 1596, 2022
82022
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