Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 12 (1), 1-222, 2016 | 11000* | 2016 |
Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 12 (1), 1-223, 2016 | 2834* | 2016 |
C. elegans in high-throughput drug discovery LP O'Reilly, CJ Luke, DH Perlmutter, GA Silverman, SC Pak Advanced drug delivery reviews 69, 247-253, 2014 | 284 | 2014 |
Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis GA Silverman, JC Whisstock, DJ Askew, SC Pak, CJ Luke, S Cataltepe, ... Cellular and Molecular Life Sciences CMLS 61 (3), 301-325, 2004 | 216 | 2004 |
Automated High-Content Live Animal Drug Screening Using C. elegans Expressing the Aggregation Prone Serpin α1-antitrypsin Z SJ Gosai, JH Kwak, CJ Luke, OS Long, DE King, KJ Kovatch, ... PloS one 5 (11), e15460, 2010 | 213 | 2010 |
An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury CJ Luke, SC Pak, YS Askew, TL Naviglia, DJ Askew, SM Nobar, ... Cell 130 (6), 1108-1119, 2007 | 208 | 2007 |
Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems GA Silverman, JC Whisstock, SP Bottomley, JA Huntington, D Kaiserman, ... Journal of Biological Chemistry 285 (32), 24299-24305, 2010 | 167 | 2010 |
Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 12 (1), 1-222, 2016 | 166 | 2016 |
Modeling molecular and cellular aspects of human disease using the nematode Caenorhabditis elegans GA Silverman, CJ Luke, SR Bhatia, OS Long, AC Vetica, DH Perlmutter, ... Pediatric research 65 (1), 10-18, 2009 | 126 | 2009 |
Serpins flex their muscle: II. Structural insights into target peptidase recognition, polymerization, and transport functions JC Whisstock, GA Silverman, PI Bird, SP Bottomley, D Kaiserman, ... Journal of Biological Chemistry 285 (32), 24307-24312, 2010 | 125 | 2010 |
Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells Y Uemura, SC Pak, C Luke, S Çataltepe, C Tsu, C Schick, Y Kamachi, ... International journal of cancer 89 (4), 368-377, 2000 | 95 | 2000 |
The serpin SQN-5 is a dual mechanistic-class inhibitor of serine and cysteine proteinases M Al-Khunaizi, CJ Luke, YS Askew, SC Pak, DJ Askew, S Cataltepe, ... Biochemistry 41 (9), 3189-3199, 2002 | 88 | 2002 |
Super-CHO—A cell line capable of autocrine growth under fully defined protein-free conditions SCO Pak, SMN Hunt, MW Bridges, MJ Sleigh, PP Gray Cytotechnology 22 (1), 139-146, 1996 | 80 | 1996 |
Lysosomal storage and albinism due to effects of a de novo CLCN7 variant on lysosomal acidification ER Nicoli, MR Weston, M Hackbarth, A Becerril, A Larson, WM Zein, ... The American Journal of Human Genetics 104 (6), 1127-1138, 2019 | 75 | 2019 |
SERPINB12 is a novel member of the human ov-serpin family that is widely expressed and inhibits trypsin-like serine proteinases YS Askew, SC Pak, CJ Luke, DJ Askew, S Cataltepe, DR Mills, H Kato, ... Journal of Biological Chemistry 276 (52), 49320-49330, 2001 | 71 | 2001 |
Model organisms contribute to diagnosis and discovery in the undiagnosed diseases network: current state and a future vision D Baldridge, MF Wangler, AN Bowman, S Yamamoto, T Schedl, SC Pak, ... Orphanet journal of rare diseases 16 (1), 1-17, 2021 | 68 | 2021 |
Serum squamous cell carcinoma antigen as an early indicator of response during therapy of cervical cancer S Markovina, S Wang, LE Henke, CJ Luke, SC Pak, T DeWees, JD Pfeifer, ... British journal of cancer 118 (1), 72-78, 2018 | 68 | 2018 |
Caenorhabditis elegans: a model system for anti-cancer drug discovery and therapeutic target identification RA Kobet, X Pan, B Zhang, SC Pak, AS Asch, MH Lee Biomolecules & therapeutics 22 (5), 371, 2014 | 63 | 2014 |
Inhibition of the cysteine proteinases cathepsins K and L by the serpin headpin (SERPINB13): a kinetic analysis A Jayakumar, Y Kang, MJ Frederick, SC Pak, Y Henderson, PR Holton, ... Archives of Biochemistry and Biophysics 409 (2), 367-374, 2003 | 61 | 2003 |
Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy YM Oh, SW Lee, WK Kim, S Chen, VA Church, K Cates, T Li, B Zhang, ... Nature neuroscience, 1-14, 2022 | 57 | 2022 |