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Stephen C. Pak
Stephen C. Pak
Associate Professor of Pediatrics, Washington University School of Medicine in St Louis
在 wustl.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-222, 2016
11000*2016
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-223, 2016
2834*2016
C. elegans in high-throughput drug discovery
LP O'Reilly, CJ Luke, DH Perlmutter, GA Silverman, SC Pak
Advanced drug delivery reviews 69, 247-253, 2014
2842014
Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis
GA Silverman, JC Whisstock, DJ Askew, SC Pak, CJ Luke, S Cataltepe, ...
Cellular and Molecular Life Sciences CMLS 61 (3), 301-325, 2004
2162004
Automated High-Content Live Animal Drug Screening Using C. elegans Expressing the Aggregation Prone Serpin α1-antitrypsin Z
SJ Gosai, JH Kwak, CJ Luke, OS Long, DE King, KJ Kovatch, ...
PloS one 5 (11), e15460, 2010
2132010
An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury
CJ Luke, SC Pak, YS Askew, TL Naviglia, DJ Askew, SM Nobar, ...
Cell 130 (6), 1108-1119, 2007
2082007
Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems
GA Silverman, JC Whisstock, SP Bottomley, JA Huntington, D Kaiserman, ...
Journal of Biological Chemistry 285 (32), 24299-24305, 2010
1672010
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-222, 2016
1662016
Modeling molecular and cellular aspects of human disease using the nematode Caenorhabditis elegans
GA Silverman, CJ Luke, SR Bhatia, OS Long, AC Vetica, DH Perlmutter, ...
Pediatric research 65 (1), 10-18, 2009
1262009
Serpins flex their muscle: II. Structural insights into target peptidase recognition, polymerization, and transport functions
JC Whisstock, GA Silverman, PI Bird, SP Bottomley, D Kaiserman, ...
Journal of Biological Chemistry 285 (32), 24307-24312, 2010
1252010
Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells
Y Uemura, SC Pak, C Luke, S Çataltepe, C Tsu, C Schick, Y Kamachi, ...
International journal of cancer 89 (4), 368-377, 2000
952000
The serpin SQN-5 is a dual mechanistic-class inhibitor of serine and cysteine proteinases
M Al-Khunaizi, CJ Luke, YS Askew, SC Pak, DJ Askew, S Cataltepe, ...
Biochemistry 41 (9), 3189-3199, 2002
882002
Super-CHO—A cell line capable of autocrine growth under fully defined protein-free conditions
SCO Pak, SMN Hunt, MW Bridges, MJ Sleigh, PP Gray
Cytotechnology 22 (1), 139-146, 1996
801996
Lysosomal storage and albinism due to effects of a de novo CLCN7 variant on lysosomal acidification
ER Nicoli, MR Weston, M Hackbarth, A Becerril, A Larson, WM Zein, ...
The American Journal of Human Genetics 104 (6), 1127-1138, 2019
752019
SERPINB12 is a novel member of the human ov-serpin family that is widely expressed and inhibits trypsin-like serine proteinases
YS Askew, SC Pak, CJ Luke, DJ Askew, S Cataltepe, DR Mills, H Kato, ...
Journal of Biological Chemistry 276 (52), 49320-49330, 2001
712001
Model organisms contribute to diagnosis and discovery in the undiagnosed diseases network: current state and a future vision
D Baldridge, MF Wangler, AN Bowman, S Yamamoto, T Schedl, SC Pak, ...
Orphanet journal of rare diseases 16 (1), 1-17, 2021
682021
Serum squamous cell carcinoma antigen as an early indicator of response during therapy of cervical cancer
S Markovina, S Wang, LE Henke, CJ Luke, SC Pak, T DeWees, JD Pfeifer, ...
British journal of cancer 118 (1), 72-78, 2018
682018
Caenorhabditis elegans: a model system for anti-cancer drug discovery and therapeutic target identification
RA Kobet, X Pan, B Zhang, SC Pak, AS Asch, MH Lee
Biomolecules & therapeutics 22 (5), 371, 2014
632014
Inhibition of the cysteine proteinases cathepsins K and L by the serpin headpin (SERPINB13): a kinetic analysis
A Jayakumar, Y Kang, MJ Frederick, SC Pak, Y Henderson, PR Holton, ...
Archives of Biochemistry and Biophysics 409 (2), 367-374, 2003
612003
Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy
YM Oh, SW Lee, WK Kim, S Chen, VA Church, K Cates, T Li, B Zhang, ...
Nature neuroscience, 1-14, 2022
572022
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