Effect of acute dietary standardization on the urinary, plasma, and salivary metabolomic profiles of healthy humans MC Walsh, L Brennan, JPG Malthouse, HM Roche, MJ Gibney The American journal of clinical nutrition 84 (3), 531-539, 2006 | 360 | 2006 |
A reporter group delivery system with both absolute and selective specificity for thiol groups and an improved fluorescent probe containing the 7-nitrobenzo-2-oxa-1, 3-diazole … T Stuchbury, M Shipton, R Norris, JPG Malthouse, K Brocklehurst, ... Biochemical Journal 151 (2), 417-432, 1975 | 236 | 1975 |
A nuclear magnetic resonance-based demonstration of substantial oxidative l-alanine metabolism and l-alanine-enhanced glucose metabolism in a clonal pancreatic β-cell line … L Brennan, A Shine, C Hewage, JPG Malthouse, KM Brindle, ... Diabetes 51 (6), 1714-1721, 2002 | 147 | 2002 |
Vinyl sulfone-based peptidomimetics as anti-trypanosomal agents: design, synthesis, biological and computational evaluation E Dunny, W Doherty, P Evans, JPG Malthouse, D Nolan, AJS Knox Journal of Medicinal Chemistry 56 (17), 6638-6650, 2013 | 112 | 2013 |
Differences in the interaction of the catalytic groups of the active centres of actinidin and papain Rapid purification of fully active actinidin by covalent chromatography and … K Brocklehurst, BS Baines, JP Malthouse Biochemical Journal 197 (3), 739-746, 1981 | 102 | 1981 |
13C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and γ-glutamyl cycle activity in a clonal pancreatic beta-cell line L Brennan, M Corless, C Hewage, JPG Malthouse, NH McClenaghan, ... Diabetologia 46, 1512-1521, 2003 | 87 | 2003 |
Preparation of fully active ficin from Ficus glabrata by covalent chromatography and characterization of its active centre by using 2,2'-depyridyl disulphide as a … JP Malthouse, K Brocklehurst Biochemical Journal 159 (2), 221-234, 1976 | 76 | 1976 |
Carbon-13 NMR study of the stereospecificity of the thiohemiacetals formed on inhibition of papain by specific enantiomeric aldehydes NE Mackenzie, SK Grant, AI Scott, JPG Malthouse Biochemistry 25 (8), 2293-2298, 1986 | 54 | 1986 |
Detection of a tetrahedral adduct in a trypsin-chloromethyl ketone specific inhibitor complex by carbon-13 NMR JPG Malthouse, NE Mackenzie, ASF Boyd, AI Scott Journal of the American Chemical Society 105 (6), 1685-1686, 1983 | 54 | 1983 |
Mechanism of the reaction of papain with substrate-derived diazomethyl ketones. Implications for the difference in site specificity of halomethyl ketones for serine proteinases … K Brocklehurst, JPG Malthouse Biochemical Journal 175 (2), 761-764, 1978 | 54 | 1978 |
Studying Enzyme Mechanism by 13C Nuclear Magnetic Resonance NE Mackenzie, JPG Malthouse, AI Scott Science 225 (4665), 883-889, 1984 | 50 | 1984 |
Structure and stereochemistry of tetrahedral inhibitor complexes of papain by direct NMR observation MP Gamcsik, JPG Malthouse, WU Primrose, NE Mackenzie, ASF Boyd, ... Journal of the American Chemical Society 105 (20), 6324-6325, 1983 | 50 | 1983 |
A study of the stabilization of tetrahedral adducts by trypsin and δ-chymotrypsin MD Finucane, JPG Malthouse Biochemical Journal 286 (3), 889-900, 1992 | 46 | 1992 |
Coupling of [33S]sulphur to molybdenum(V) in different reduced forms of xanthine oxidase JPG Malthouse, GN George, DJ Lowe, RC Bray Biochemical Journal 199 (3), 629-637, 1981 | 45 | 1981 |
Carbon-13 NMR study of the ionizations within a trypsin-chloromethyl ketone inhibitor complex JPG Malthouse, WU Primrose, NE Mackenzie, AI Scott Biochemistry 24 (14), 3478-3487, 1985 | 44 | 1985 |
Differences in the chemical and catalytic characteristics of two crystallographically ‘identical’enzyme catalytic sites. Characterization of actinidin and papain by a … E Salih, JPG Malthouse, D Kowlessur, M Jarvis, M O'Driscoll, ... Biochemical Journal 247 (1), 181-193, 1987 | 43 | 1987 |
NMR and alanine scan studies of glucose-dependent insulinotropic polypeptide in water I Alana, JC Parker, VA Gault, PR Flatt, FPM O'Harte, JPG Malthouse, ... Journal of Biological Chemistry 281 (24), 16370-16376, 2006 | 41 | 2006 |
Reactivities of neutral and cationic forms of 2, 2′-dipyridyl disulphide towards thiolate anions. Detection of differences between the active centres of actinidin, papain and … K Brocklehurst, T Stuchbury, JPG Malthouse Biochemical Journal 183 (2), 233-238, 1979 | 39 | 1979 |
The case for assigning a value of approximately 4 to pKa-i of the essential histidine-cysteine interactive systems of papain, bromelain and ficin M Shipton, MP Kierstan, JP Malthouse, T Stuchbury, K Brocklehurst FEBS lett 50 (3), 365-368, 1975 | 38 | 1975 |
The bioactive conformation of glucose‐dependent insulinotropic polypeptide by NMR and CD spectroscopy I Alaña, JPG Malthouse, FPM O'Harte, CM Hewage Proteins: Structure, Function, and Bioinformatics 68 (1), 92-99, 2007 | 37 | 2007 |