High-carbohydrate, high-fat diet–induced metabolic syndrome and cardiovascular remodeling in rats SK Panchal, H Poudyal, A Iyer, R Nazer, A Alam, V Diwan, K Kauter, ... Journal of cardiovascular pharmacology 57 (5), 611-624, 2011 | 595 | 2011 |
Inflammatory lipid mediators in adipocyte function and obesity A Iyer, DP Fairlie, JB Prins, BD Hammock, L Brown Nature Reviews Endocrinology 6 (2), 71-82, 2010 | 368 | 2010 |
Antifibrotic activity of an inhibitor of histone deacetylases in DOCA‐salt hypertensive rats A Iyer, A Fenning, J Lim, GT Le, RC Reid, MA Halili, DP Fairlie, L Brown British journal of pharmacology 159 (7), 1408-1417, 2010 | 155 | 2010 |
C5aR and C3aR antagonists each inhibit diet‐induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling J Lim, A Iyer, JY Suen, V Seow, RC Reid, L Brown, DP Fairlie The FASEB Journal 27 (2), 822-831, 2013 | 151 | 2013 |
Diet‐induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism J Lim, A Iyer, L Liu, JY Suen, RJ Lohman, V Seow, MK Yau, L Brown, ... The FASEB Journal 27 (12), 4757-4767, 2013 | 132 | 2013 |
Lysine acetylation in obesity, diabetes and metabolic disease A Iyer, DP Fairlie, L Brown Immunology and cell biology 90 (1), 39-46, 2012 | 131 | 2012 |
The DOCA-salt hypertensive rat as a model of cardiovascular oxidative and inflammatory stress A Iyer, V Chan, L Brown Current cardiology reviews 6 (4), 291-297, 2010 | 121 | 2010 |
Histone deacetylases in monocyte/macrophage development, activation and metabolism: refining HDAC targets for inflammatory and infectious diseases K Das Gupta, MR Shakespear, A Iyer, DP Fairlie, MJ Sweet Clinical & translational immunology 5 (1), e62, 2016 | 113 | 2016 |
Resveratrol improves cardiovascular function in DOCA-salt hypertensive rats V Chan, A Fenning, A Iyer, A Hoey, L Brown Current Pharmaceutical Biotechnology 12 (3), 429-436, 2011 | 108 | 2011 |
Inflammatory responses induced by lipopolysaccharide are amplified in primary human monocytes but suppressed in macrophages by complement protein C5a V Seow, J Lim, A Iyer, JY Suen, JK Ariffin, DM Hohenhaus, MJ Sweet, ... The Journal of Immunology 191 (8), 4308-4316, 2013 | 102 | 2013 |
Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages MR Shakespear, DM Hohenhaus, GM Kelly, NA Kamal, P Gupta, ... Journal of Biological Chemistry 288 (35), 25362-25374, 2013 | 101 | 2013 |
Potential health benefits of Indian spices in the symptoms of the metabolic syndrome: a review A Iyer, S Panchal, H Poudyal, L Brown CSIR, 2009 | 100 | 2009 |
Towards isozyme-selective HDAC inhibitors for interrogating disease P Gupta, R C Reid, A Iyer, M J Sweet, D P Fairlie Current topics in medicinal chemistry 12 (14), 1479-1499, 2012 | 93 | 2012 |
Evaluation of the chronic complications of diabetes in a high fructose diet in rats J Patel, A Iyer, L Brown CSIR, 2009 | 90 | 2009 |
The cardiovascular nutrapharmacology of resveratrol: pharmacokinetics, molecular mechanisms and therapeutic potential P A Kroon, A Iyer, P Chunduri, V Chan, L Brown Current Medicinal Chemistry 17 (23), 2442-2455, 2010 | 89 | 2010 |
Pharmacological inhibition of soluble epoxide hydrolase ameliorates diet‐induced metabolic syndrome in rats A Iyer, K Kauter, MA Alam, SH Hwang, C Morisseau, BD Hammock, ... Journal of Diabetes Research 2012 (1), 758614, 2012 | 84 | 2012 |
Crystal structures of protein-bound cyclic peptides AK Malde, TA Hill, A Iyer, DP Fairlie Chemical reviews 119 (17), 9861-9914, 2019 | 69 | 2019 |
An inhibitor of phospholipase A2 group IIA modulates adipocyte signaling and protects against diet-induced metabolic syndrome in rats A Iyer, J Lim, H Poudyal, RC Reid, JY Suen, J Webster, JB Prins, ... Diabetes 61 (9), 2320-2329, 2012 | 61 | 2012 |
An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable … DM Hohenhaus, K Schaale, KA Le Cao, V Seow, A Iyer, DP Fairlie, ... Immunobiology 218 (11), 1345-1353, 2013 | 60 | 2013 |
Class IIa histone deacetylases drive toll-like receptor-inducible glycolysis and macrophage inflammatory responses via pyruvate kinase M2 KD Gupta, MR Shakespear, JEB Curson, AMV Murthy, A Iyer, MP Hodson, ... Cell reports 30 (8), 2712-2728. e8, 2020 | 57 | 2020 |