| The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43 I Kimura, K Ozawa, D Inoue, T Imamura, K Kimura, T Maeda, K Terasawa, ... Nature communications 4 (1), 1829, 2013 | 1526 | 2013 |
| Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo H Inoue, W Ogawa, M Ozaki, S Haga, M Matsumoto, K Furukawa, ... Nature medicine 10 (2), 168-174, 2004 | 431 | 2004 |
| Role of hepatic STAT3 in brain-insulin action on hepatic glucose production H Inoue, W Ogawa, A Asakawa, Y Okamoto, A Nishizawa, M Matsumoto, ... Cell metabolism 3 (4), 267-275, 2006 | 368 | 2006 |
| CCR5 plays a critical role in obesity-induced adipose tissue inflammation and insulin resistance by regulating both macrophage recruitment and M1/M2 status H Kitade, K Sawamoto, M Nagashimada, H Inoue, Y Yamamoto, Y Sai, ... Diabetes 61 (7), 1680-1690, 2012 | 315 | 2012 |
| Stat3 protects against Fas-induced liver injury by redox-dependent and-independent mechanisms S Haga, K Terui, HQ Zhang, S Enosawa, W Ogawa, H Inoue, T Okuyama, ... The Journal of clinical investigation 112 (7), 989-998, 2003 | 303 | 2003 |
| The Creb1 coactivator Crtc1 is required for energy balance and fertility JY Altarejos, N Goebel, MD Conkright, H Inoue, J Xie, CM Arias, ... Nature medicine 14 (10), 1112-1117, 2008 | 234 | 2008 |
| PKCλ in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity M Matsumoto, W Ogawa, K Akimoto, H Inoue, K Miyake, K Furukawa, ... The Journal of clinical investigation 112 (6), 935-944, 2003 | 225 | 2003 |
| Macrophage-inducible C-type lectin underlies obesity-induced adipose tissue fibrosis M Tanaka, K Ikeda, T Suganami, C Komiya, K Ochi, I Shirakawa, ... Nature communications 5 (1), 4982, 2014 | 204 | 2014 |
| Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity Y Wang, H Inoue, K Ravnskjaer, K Viste, N Miller, Y Liu, S Hedrick, L Vera, ... Proceedings of the National Academy of Sciences 107 (7), 3087-3092, 2010 | 180 | 2010 |
| CRTC3 links catecholamine signalling to energy balance Y Song, J Altarejos, MO Goodarzi, H Inoue, X Guo, R Berdeaux, JH Kim, ... Nature 468 (7326), 933-939, 2010 | 178 | 2010 |
| Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element binding protein 1c and … M Matsumoto, W Ogawa, K Teshigawara, H Inoue, K Miyake, H Sakaue, ... Diabetes 51 (6), 1672-1680, 2002 | 147 | 2002 |
| Dok1 mediates high-fat diet–induced adipocyte hypertrophy and obesity through modulation of PPAR-γ phosphorylation T Hosooka, T Noguchi, K Kotani, T Nakamura, H Sakaue, H Inoue, ... Nature medicine 14 (2), 188-193, 2008 | 131 | 2008 |
| Compensatory recovery of liver mass by Akt-mediated hepatocellular hypertrophy in liver-specific STAT3-deficient mice S Haga, W Ogawa, H Inoue, K Terui, T Ogino, R Igarashi, K Takeda, ... Journal of hepatology 43 (5), 799-807, 2005 | 131 | 2005 |
| Role of KLF15 in regulation of hepatic gluconeogenesis and metformin action M Takashima, W Ogawa, K Hayashi, H Inoue, S Kinoshita, Y Okamoto, ... Diabetes 59 (7), 1608-1615, 2010 | 129 | 2010 |
| Ablation of C/EBPβ alleviates ER stress and pancreatic β cell failure through the GRP78 chaperone in mice T Matsuda, Y Kido, S Asahara, T Kaisho, T Tanaka, N Hashimoto, ... The Journal of clinical investigation 120 (1), 115-126, 2010 | 118 | 2010 |
| Central insulin action activates Kupffer cells by suppressing hepatic vagal activation via the nicotinic alpha 7 acetylcholine receptor K Kimura, M Tanida, N Nagata, Y Inaba, H Watanabe, M Nagashimada, ... Cell Reports 14 (10), 2362-2374, 2016 | 98 | 2016 |
| Endoplasmic reticulum stress inhibits STAT3-dependent suppression of hepatic gluconeogenesis via dephosphorylation and deacetylation K Kimura, T Yamada, M Matsumoto, Y Kido, T Hosooka, S Asahara, ... Diabetes 61 (1), 61-73, 2012 | 98 | 2012 |
| CITED2 links hormonal signaling to PGC-1α acetylation in the regulation of gluconeogenesis M Sakai, M Matsumoto, T Tujimura, C Yongheng, T Noguchi, K Inagaki, ... Nature medicine 18 (4), 612-617, 2012 | 86 | 2012 |
| Sirt2 facilitates hepatic glucose uptake by deacetylating glucokinase regulatory protein H Watanabe, Y Inaba, K Kimura, M Matsumoto, S Kaneko, M Kasuga, ... Nature communications 9 (1), 30, 2018 | 80 | 2018 |
| PKCλ regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic β cells N Hashimoto, Y Kido, T Uchida, T Matsuda, K Suzuki, H Inoue, ... The Journal of clinical investigation 115 (1), 138-145, 2005 | 79 | 2005 |
