Thermodynamic stability of wild-type and mutant p53 core domain AN Bullock, J Henckel, BS DeDecker, CM Johnson, PV Nikolova, ... Proceedings of the National Academy of Sciences 94 (26), 14338-14342, 1997 | 524 | 1997 |
A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants A Friedler, LO Hansson, DB Veprintsev, SMV Freund, TM Rippin, ... Proceedings of the National Academy of Sciences 99 (2), 937-942, 2002 | 346 | 2002 |
Semirational design of active tumor suppressor p53 DNA binding domain with enhanced stability PV Nikolova, J Henckel, DP Lane, AR Fersht Proceedings of the National Academy of Sciences 95 (25), 14675-14680, 1998 | 301 | 1998 |
Mechanism of rescue of common p53 cancer mutations by second‐site suppressor mutations PV Nikolova, KB Wong, B DeDecker, J Henckel, AR Fersht The EMBO journal, 2000 | 209 | 2000 |
Whole cell biocatalysis in nonconventional media P Nikolova, OP Ward Journal of industrial microbiology 12, 76-86, 1993 | 121 | 1993 |
Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax S Patel, R George, F Autore, F Fraternali, JE Ladbury, PV Nikolova Nucleic acids research 36 (16), 5139-5151, 2008 | 74 | 2008 |
Production of L‐phenylacetyl carbinol by biotransformation: Product and by‐product formation and activities of the key enzymes in wild‐type and ADH isoenzyme mutants of … P Nikolova, OP Ward Biotechnology and bioengineering 38 (5), 493-498, 1991 | 58 | 1991 |
Insights into the Conformations of Three Structurally Diverse Proteins: Cytochrome c, p53, and MDM2, Provided by Variable-Temperature Ion Mobility Mass … ER Dickinson, E Jurneczko, KJ Pacholarz, DJ Clarke, M Reeves, KL Ball, ... Analytical chemistry 87 (6), 3231-3238, 2015 | 45 | 2015 |
Intrinsic disorder in proteins: a challenge for (un) structural biology met by ion mobility–mass spectrometry E Jurneczko, F Cruickshank, M Porrini, P Nikolova, IDG Campuzano, ... Biochemical Society Transactions 40 (5), 1021-1026, 2012 | 45 | 2012 |
Probing the conformational diversity of cancer‐associated mutations in p53 with ion‐mobility mass spectrometry E Jurneczko, F Cruickshank, M Porrini, DJ Clarke, IDG Campuzano, ... Angewandte Chemie 125 (16), 4466-4470, 2013 | 42 | 2013 |
Whole cell yeast biotransformations in two-phase systems: effect of solvent on product formation and cell structure P Nikolova, OP Ward Journal of industrial microbiology 10, 169-177, 1992 | 42 | 1992 |
Reductive biotransformation by wild type and mutant strains of Saccharomyces cerevisiae in aqueous‐organic solvent biphasic systems P Nikolova, OP Ward Biotechnology and bioengineering 39 (8), 870-876, 1992 | 39 | 1992 |
Mutants of the tumour suppressor p53 L1 loop as second-site suppressors for restoring DNA binding to oncogenic p53 mutations: structural and biochemical insights A Merabet, H Houlleberghs, K Maclagan, E Akanho, TTT Bui, B Pagano, ... Biochemical Journal 427 (2), 225-236, 2010 | 35 | 2010 |
Thermostability and irreversible activity loss of exoglucanase/xylanase Cex from Cellulomonas fimi PV Nikolova, AL Creagh, SJB Duff, CA Haynes Biochemistry 36 (6), 1381-1388, 1997 | 31 | 1997 |
The p73 DNA binding domain displays enhanced stability relative to its homologue, the tumor suppressor p53, and exhibits cooperative DNA binding S Patel, TTT Bui, AF Drake, F Fraternali, PV Nikolova Biochemistry 47 (10), 3235-3244, 2008 | 29 | 2008 |
A thermodynamic study of aqueous acetonitrile: excess chemical potentials, partial molar enthalpies, entropies and volumes, and fluctuations PV Nikolova, SJB Duff, P Westh, CA Haynes, Y Kasahara, K Nishikawa, ... Canadian Journal of Chemistry 78 (12), 1553-1560, 2000 | 28 | 2000 |
Consequences of point mutations in melanoma-associated antigen 4 (MAGE-A4) protein: Insights from structural and biophysical studies Y Hagiwara, L Sieverling, F Hanif, J Anton, ER Dickinson, TTT Bui, ... Scientific reports 6 (1), 25182, 2016 | 25 | 2016 |
Structure and stability insights into tumour suppressor p53 evolutionary related proteins B Pagano, A Jama, P Martinez, E Akanho, TTT Bui, AF Drake, F Fraternali, ... PLoS One 8 (10), e76014, 2013 | 25 | 2013 |
Utilising ion mobility-mass spectrometry to interrogate macromolecules: Factor H complement control protein modules 10–15 and 19–20 and the DNA-binding core domain of tumour … PA Faull, HV Florance, CQ Schmidt, N Tomczyk, PN Barlow, TR Hupp, ... International Journal of Mass Spectrometry 298 (1-3), 99-110, 2010 | 21 | 2010 |
Effect of support matrix on ratio of product to by-product formation in L-phenylacetyl carbinol synthesis P Nikolova, OP Ward Biotechnology letters 16, 7-10, 1994 | 19 | 1994 |