| Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds D Huangfu, R Maehr, W Guo, A Eijkelenboom, M Snitow, AE Chen, ... Nature biotechnology 26 (7), 795-797, 2008 | 2160 | 2008 |
| Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2 D Huangfu, K Osafune, R Maehr, W Guo, A Eijkelenboom, S Chen, ... Nature biotechnology 26 (11), 1269-1275, 2008 | 1912 | 2008 |
| Hedgehog signalling in the mouse requires intraflagellar transport proteins D Huangfu, A Liu, AS Rakeman, NS Murcia, L Niswander, KV Anderson Nature 426 (6962), 83-87, 2003 | 1601 | 2003 |
| A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog JK Ichida, J Blanchard, K Lam, EY Son, JE Chung, D Egli, KM Loh, ... Cell stem cell 5 (5), 491-503, 2009 | 965 | 2009 |
| Cilia and Hedgehog responsiveness in the mouse D Huangfu, KV Anderson Proceedings of the National Academy of Sciences 102 (32), 11325-11330, 2005 | 934 | 2005 |
| Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates D Huangfu, KV Anderson Oxford University Press for The Company of Biologists Limited 133 (1), 3-14, 2006 | 618 | 2006 |
| An iCRISPR platform for rapid, multiplexable, and inducible genome editing in human pluripotent stem cells F González, Z Zhu, ZD Shi, K Lelli, N Verma, QV Li, D Huangfu Cell stem cell 15 (2), 215-226, 2014 | 535 | 2014 |
| CRISPR/Cas9-based engineering of the epigenome J Pulecio, N Verma, E Mejía-Ramírez, D Huangfu, A Raya Cell stem cell 21 (4), 431-447, 2017 | 279 | 2017 |
| All β cells contribute equally to islet growth and maintenance K Brennand, D Huangfu, D Melton PLoS biology 5 (7), e163, 2007 | 269 | 2007 |
| Human pluripotent stem cells: an emerging model in developmental biology Z Zhu, D Huangfu Development 140 (4), 705-717, 2013 | 248 | 2013 |
| Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling T Caspary, MJ Garcıa-Garcıa, D Huangfu, JT Eggenschwiler, MR Wyler, ... Current biology 12 (18), 1628-1632, 2002 | 224 | 2002 |
| Genome editing of lineage determinants in human pluripotent stem cells reveals mechanisms of pancreatic development and diabetes Z Zhu, QV Li, K Lee, BP Rosen, F González, CL Soh, D Huangfu Cell stem cell 18 (6), 755-768, 2016 | 185 | 2016 |
| TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells N Verma, H Pan, LC Doré, A Shukla, QV Li, B Pelham-Webb, V Teijeiro, ... Nature genetics 50 (1), 83-95, 2018 | 178 | 2018 |
| Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells AG Kotini, CJ Chang, I Boussaad, JJ Delrow, EK Dolezal, AB Nagulapally, ... Nature biotechnology 33 (6), 646-655, 2015 | 164 | 2015 |
| Genome editing in hPSCs reveals GATA6 haploinsufficiency and a genetic interaction with GATA4 in human pancreatic development ZD Shi, K Lee, D Yang, S Amin, N Verma, QV Li, Z Zhu, CL Soh, R Kumar, ... Cell stem cell 20 (5), 675-688. e6, 2017 | 161 | 2017 |
| The p53 family coordinates Wnt and nodal inputs in mesendodermal differentiation of embryonic stem cells Q Wang, Y Zou, S Nowotschin, SY Kim, QV Li, CL Soh, J Su, C Zhang, ... Cell Stem Cell 20 (1), 70-86, 2017 | 160 | 2017 |
| Analysis of mouse embryonic patterning and morphogenesis by forward genetics MJ García-García, JT Eggenschwiler, T Caspary, HL Alcorn, MR Wyler, ... Proceedings of the National Academy of Sciences 102 (17), 5913-5919, 2005 | 153 | 2005 |
| FOXA2 is required for enhancer priming during pancreatic differentiation K Lee, H Cho, RW Rickert, QV Li, J Pulecio, CS Leslie, D Huangfu Cell reports 28 (2), 382-393. e7, 2019 | 126 | 2019 |
| Genome-scale screens identify JNK–JUN signaling as a barrier for pluripotency exit and endoderm differentiation QV Li, G Dixon, N Verma, BP Rosen, M Gordillo, R Luo, C Xu, Q Wang, ... Nature genetics 51 (6), 999-1010, 2019 | 107 | 2019 |
| A CRISPR/Cas-mediated selection-free knockin strategy in human embryonic stem cells Z Zhu, N Verma, F González, ZD Shi, D Huangfu Stem cell reports 4 (6), 1103-1111, 2015 | 104 | 2015 |
Qing Li, PhDTessera Therapeutics, CRISPR Therapeutics, Memorial Sloan Kettering Cancer Center在 mskcc.org 的电子邮件经过验证
