| Biased allosteric modulation at the CaS receptor engendered by structurally diverse calcimimetics AE Cook, SN Mistry, KJ Gregory, SGB Furness, PM Sexton, PJ Scammells, ... British journal of pharmacology 172 (1), 185-200, 2015 | 87 | 2015 |
| Synthesis and Pharmacological Profiling of Analogues of Benzyl Quinolone Carboxylic Acid (BQCA) as Allosteric Modulators of the M1 Muscarinic Receptor SN Mistry, C Valant, PM Sexton, B Capuano, A Christopoulos, ... Journal of medicinal chemistry 56 (12), 5151-5172, 2013 | 77 | 2013 |
| Molecular determinants of allosteric modulation at the M1 muscarinic acetylcholine receptor A Abdul-Ridha, L Lopez, P Keov, DM Thal, SN Mistry, PM Sexton, ... Journal of Biological Chemistry 289 (9), 6067-6079, 2014 | 73 | 2014 |
| Two-Pronged Attack: Dual Inhibition of Plasmodium falciparum M1 and M17 Metalloaminopeptidases by a Novel Series of Hydroxamic Acid-Based Inhibitors SN Mistry, N Drinkwater, C Ruggeri, KK Sivaraman, S Loganathan, ... Journal of medicinal chemistry 57 (21), 9168-9183, 2014 | 69 | 2014 |
| Mechanistic insights into allosteric structure-function relationships at the M1 muscarinic acetylcholine receptor A Abdul-Ridha, JR Lane, SN Mistry, L Lopez, PM Sexton, PJ Scammells, ... Journal of Biological Chemistry 289 (48), 33701-33711, 2014 | 64 | 2014 |
| Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions N Drinkwater, NB Vinh, SN Mistry, RS Bamert, C Ruggeri, JP Holleran, ... European journal of medicinal chemistry 110, 43-64, 2016 | 63 | 2016 |
| Discovery of a Novel Class of Negative Allosteric Modulator of the Dopamine D2 Receptor Through Fragmentation of a Bitopic Ligand SN Mistry, J Shonberg, CJ Draper-Joyce, C Klein Herenbrink, M Michino, ... Journal of medicinal chemistry 58 (17), 6819-6843, 2015 | 55 | 2015 |
| Synthesis and Characterization of High-Affinity 4,4-Difluoro-4-bora-3a,4a-diaza-s-indacene-Labeled Fluorescent Ligands for Human β-Adrenoceptors JG Baker, LA Adams, K Salchow, SN Mistry, RJ Middleton, SJ Hill, ... Journal of medicinal chemistry 54 (19), 6874-6887, 2011 | 52 | 2011 |
| Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa F Soukarieh, R Liu, M Romero, SN Roberston, W Richardson, S Lucanto, ... Frontiers in Chemistry 8, 204, 2020 | 46 | 2020 |
| Structure–Activity Study of N-((trans)-4-(2-(7-Cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)-1H-indole-2-carboxamide (SB269652), a Bitopic Ligand That Acts as a … J Shonberg, C Draper-Joyce, SN Mistry, A Christopoulos, PJ Scammells, ... Journal of Medicinal Chemistry 58 (13), 5287-5307, 2015 | 45 | 2015 |
| Screening the Medicines for Malaria Venture "Malaria Box" against the Plasmodium falciparum Aminopeptidases, M1, M17 and M18 A Paiardini, RS Bamert, K Kannan-Sivaraman, N Drinkwater, SN Mistry, ... PloS one 10 (2), e0115859, 2015 | 41 | 2015 |
| A Thieno[2,3-d]pyrimidine Scaffold Is a Novel Negative Allosteric Modulator of the Dopamine D2 Receptor TJ Fyfe, B Zarzycka, HD Lim, B Kellam, SN Mistry, V Katrich, ... Journal of Medicinal Chemistry 62 (1), 174-206, 2018 | 39 | 2018 |
| 4-Phenylpyridin-2-one Derivatives: A Novel Class of Positive Allosteric Modulator of the M1 Muscarinic Acetylcholine Receptor SN Mistry, M Jörg, H Lim, NB Vinh, PM Sexton, B Capuano, ... Journal of Medicinal Chemistry 59 (1), 388-409, 2016 | 37 | 2016 |
| Synthesis and in Vitro and in Vivo Characterization of Highly β1-Selective β-Adrenoceptor Partial Agonists SN Mistry, JG Baker, PM Fischer, SJ Hill, SM Gardiner, B Kellam Journal of Medicinal Chemistry 56 (10), 3852-3865, 2013 | 29 | 2013 |
| Positive allosteric modulation of the muscarinic M1 receptor improves efficacy of antipsychotics in mouse glutamatergic deficit models of behavior KHC Choy, DM Shackleford, DT Malone, SN Mistry, RT Patil, ... Journal of Pharmacology and Experimental Therapeutics 359 (2), 354-365, 2016 | 28 | 2016 |
| Novel selective β1-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease JG Baker, SM Gardiner, J Woolard, C Fromont, GP Jadhav, SN Mistry, ... The FASEB Journal 31 (7), 3150, 2017 | 19 | 2017 |
| Structure–Kinetic Profiling of Haloperidol Analogues at the Human Dopamine D2 Receptor TJ Fyfe, B Kellam, DA Sykes, B Capuano, PJ Scammells, JR Lane, ... Journal of Medicinal Chemistry 62 (21), 9488-9520, 2019 | 15 | 2019 |
| Novel Fused Arylpyrimidinone Based Allosteric Modulators of the M1 Muscarinic Acetylcholine Receptor SN Mistry, H Lim, M Jörg, B Capuano, A Christopoulos, JR Lane, ... ACS Chemical Neuroscience 7 (5), 647-661, 2016 | 14 | 2016 |
| Assessment of the molecular mechanisms of action of novel 4-Phenylpyridine-2-one and 6-Phenylpyrimidin-4-one allosteric modulators at the M1 muscarinic acetylcholine receptors ET van der Westhuizen, A Spathis, E Khajehali, M Jörg, SN Mistry, ... Molecular Pharmacology 94 (1), 770-783, 2018 | 12 | 2018 |
| M1 muscarinic receptor activation reduces the molecular pathology and slows the progression of prion-mediated neurodegenerative disease L Dwomoh, M Rossi, M Scarpa, E Khajehali, C Molloy, P Herzyk, ... Science Signaling 15 (760), eabm3720, 2022 | 10 | 2022 |
Peter ScammellsMonash University在 monash.edu 的电子邮件经过验证
