Genomic instability in laminopathy-based premature aging B Liu, J Wang, KM Chan, WM Tjia, W Deng, X Guan, J Huang, KM Li, ... Nature medicine 11 (7), 780-785, 2005 | 738 | 2005 |
Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice V Krishnan, MZY Chow, Z Wang, L Zhang, B Liu, X Liu, Z Zhou Proceedings of the National Academy of Sciences 108 (30), 12325-12330, 2011 | 261 | 2011 |
Impaired angiogenesis, delayed wound healing and retarded tumor growth in perlecan heparan sulfate-deficient mice Z Zhou, J Wang, R Cao, H Morita, R Soininen, KM Chan, B Liu, Y Cao, ... Cancer research 64 (14), 4699-4702, 2004 | 257 | 2004 |
Resveratrol rescues SIRT1-dependent adult stem cell decline and alleviates progeroid features in laminopathy-based progeria B Liu, S Ghosh, X Yang, H Zheng, X Liu, Z Wang, G Jin, B Zheng, ... Cell metabolism 16 (6), 738-750, 2012 | 223 | 2012 |
SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis X Tang, L Shi, N Xie, Z Liu, M Qian, F Meng, Q Xu, M Zhou, X Cao, ... Nature communications 8 (1), 318, 2017 | 190 | 2017 |
Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model B Liu, Z Wang, L Zhang, S Ghosh, H Zheng, Z Zhou Nature communications 4 (1), 1868, 2013 | 155 | 2013 |
Biomarkers of aging Aging Biomarker Consortium, H Bao, J Cao, M Chen, M Chen, W Chen, ... Science China Life Sciences 66 (5), 893-1066, 2023 | 130* | 2023 |
Lamin A is an endogenous SIRT6 activator and promotes SIRT6-mediated DNA repair S Ghosh, B Liu, Y Wang, Q Hao, Z Zhou Cell reports 13 (7), 1396-1406, 2015 | 125 | 2015 |
SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair M Tang, Z Li, C Zhang, X Lu, B Tu, Z Cao, Y Li, Y Chen, L Jiang, H Wang, ... Science advances 5 (3), eaav1118, 2019 | 108 | 2019 |
Progerin accumulation in nucleus pulposus cells impairs mitochondrial function and induces intervertebral disc degeneration and therapeutic effects of sulforaphane X Xu, D Wang, C Zheng, B Gao, J Fan, P Cheng, B Liu, L Yang, Z Luo Theranostics 9 (8), 2252, 2019 | 98 | 2019 |
Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming Y Wu, Y Li, H Zhang, Y Huang, P Zhao, Y Tang, X Qiu, Y Ying, W Li, S Ni, ... Nature cell biology 17 (6), 715-725, 2015 | 94 | 2015 |
Chromatin remodeling, DNA damage repair and aging B Liu, R KH Yip, Z Zhou Current genomics 13 (7), 533-547, 2012 | 89 | 2012 |
Lamin AC, laminopathies and premature ageing B Liu, Z Zhou Histology and histopathology, 2008 | 84 | 2008 |
MT1-MMP inactivates ADAM9 to regulate FGFR2 signaling and calvarial osteogenesis KM Chan, HLX Wong, G Jin, B Liu, R Cao, Y Cao, K Lehti, K Tryggvason, ... Developmental cell 22 (6), 1176-1190, 2012 | 83 | 2012 |
SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease W Li, W Feng, X Su, D Luo, Z Li, Y Zhou, Y Zhu, M Zhang, J Chen, B Liu, ... The Journal of clinical investigation 132 (1), 2022 | 79 | 2022 |
Vascular endothelium–targeted Sirt7 gene therapy rejuvenates blood vessels and extends life span in a Hutchinson-Gilford progeria model S Sun, W Qin, X Tang, Y Meng, W Hu, S Zhang, M Qian, Z Liu, X Cao, ... Science advances 6 (8), eaay5556, 2020 | 73 | 2020 |
HDAC8 cooperates with SMAD3/4 complex to suppress SIRT7 and promote cell survival and migration X Tang, G Li, F Su, Y Cai, L Shi, Y Meng, Z Liu, J Sun, M Wang, M Qian, ... Nucleic Acids Research 48 (6), 2912-2923, 2020 | 72 | 2020 |
Downregulation of SIRT7 by 5-fluorouracil induces radiosensitivity in human colorectal cancer M Tang, X Lu, C Zhang, C Du, L Cao, T Hou, Z Li, B Tu, Z Cao, Y Li, ... Theranostics 7 (5), 1346, 2017 | 72 | 2017 |
A SIRT1-centered circuitry regulates breast cancer stemness and metastasis L Shi, X Tang, M Qian, Z Liu, F Meng, L Fu, Z Wang, WG Zhu, JD Huang, ... Oncogene 37 (49), 6299-6315, 2018 | 71 | 2018 |
Mitophagy promotes sorafenib resistance through hypoxia-inducible ATAD3A dependent Axis H Wu, T Wang, Y Liu, X Li, S Xu, C Wu, H Zou, M Cao, G Jin, J Lang, ... Journal of Experimental & Clinical Cancer Research 39, 1-16, 2020 | 68 | 2020 |