Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis S Mi, X Lee, X Li, GM Veldman, H Finnerty, L Racie, E LaVallie, XY Tang, ... Nature 403 (6771), 785-789, 2000 | 1910 | 2000 |
Evaluation of an estrogen receptor-β agonist in animal models of human disease HA Harris, LM Albert, Y Leathurby, MS Malamas, RE Mewshaw, CP Miller, ... Endocrinology 144 (10), 4241-4249, 2003 | 423 | 2003 |
Blockade of the interleukin‐21/interleukin‐21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis DA Young, M Hegen, HLM Ma, MJ Whitters, LM Albert, L Lowe, M Senices, ... Arthritis & Rheumatism 56 (4), 1152-1163, 2007 | 384 | 2007 |
Utility of animal models for identification of potential therapeutics for rheumatoid arthritis M Hegen, JC Keith, M Collins, CL Nickerson-Nutter Annals of the rheumatic diseases 67 (11), 1505-1515, 2008 | 379 | 2008 |
Interleukin-11 promotes T cell polarization and prevents acute graft-versus-host disease after allogeneic bone marrow transplantation. GR Hill, KR Cooke, T Teshima, JM Crawford, JC Keith, YS Brinson, ... The Journal of clinical investigation 102 (1), 115-123, 1998 | 351 | 1998 |
Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-β ligands MS Malamas, ES Manas, RE McDevitt, I Gunawan, ZB Xu, MD Collini, ... Journal of medicinal chemistry 47 (21), 5021-5040, 2004 | 321 | 2004 |
Hematopoietic, immunomodulatory and epithelial effects of interleukin-11 US Schwertschlag, WL Trepicchio, KH Dykstra, JC Keith, KJ Turner, ... Leukemia 13 (9), 1307-1315, 1999 | 246 | 1999 |
Downregulation of placental syncytin expression and abnormal protein localization in pre-eclampsia X Lee, JC Keith Jr, N Stumm, I Moutsatsos, JM McCoy, CP Crum, ... Placenta 22 (10), 808-812, 2001 | 240 | 2001 |
Inhibition of the RAGE products increases survival in experimental models of severe sepsis and systemic infection EC Lutterloh, SM Opal, DD Pittman, JC Keith, XY Tan, BM Clancy, ... Critical Care 11, 1-9, 2007 | 211 | 2007 |
Identification of pathway-selective estrogen receptor ligands that inhibit NF-κB transcriptional activity CC Chadwick, S Chippari, E Matelan, L Borges-Marcucci, AM Eckert, ... Proceedings of the National Academy of Sciences 102 (7), 2543-2548, 2005 | 197 | 2005 |
Assessment of arterial stiffness, a translational medicine biomarker system for evaluation of vascular risk X Wang, JC Keith Jr, AD Struthers, GZ Feuerstein Cardiovascular therapeutics 26 (3), 214-223, 2008 | 185 | 2008 |
ERβ ligands. 3. Exploiting two binding orientations of the 2-phenylnaphthalene scaffold to achieve ERβ selectivity RE Mewshaw, RJ Edsall, C Yang, ES Manas, ZB Xu, RA Henderson, ... Journal of medicinal chemistry 48 (12), 3953-3979, 2005 | 185 | 2005 |
IL-11, a pleiotropic cytokine: exciting new effects of IL-11 on gastrointestinal mucosal biology. JC Keith Jr, L Albert, ST Sonis, CJ Pfeiffer, RG Schaub Stem Cells (Dayton, Ohio) 12, 79-89; discussion 89, 1994 | 183 | 1994 |
Recombinant soluble form of PSGL-1 accelerates thrombolysis and prevents reocclusion in a porcine model A Kumar, MP Villani, UK Patel, JC Keith Jr, RG Schaub Circulation 99 (10), 1363-1369, 1999 | 173 | 1999 |
Synthesis and biological evaluation of quinoline salicylic acids as P-selectin antagonists N Kaila, K Janz, S DeBernardo, PW Bedard, RT Camphausen, S Tam, ... Journal of medicinal chemistry 50 (1), 21-39, 2007 | 159 | 2007 |
Beneficial effects of estrogen treatment in the HLA-B27 transgenic rat model of inflammatory bowel disease DC Harnish, LM Albert, Y Leathurby, AM Eckert, A Ciarletta, M Kasaian, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 286 (1 …, 2004 | 159 | 2004 |
Immunolocalization of tumour necrosis factor-α (TNF-α) in the placental bed of normotensive and hypertensive human pregnancies R Pijnenborg, PJ McLaughlin, L Vercruysse, M Hanssens, PM Johnson, ... Placenta 19 (4), 231-239, 1998 | 146 | 1998 |
Molecular effects of recombinant human interleukin-11 in the HLA-B27 rat model of inflammatory bowel disease. RL Peterson, L Wang, L Albert, JC Keith Jr, AJ Dorner Laboratory investigation; a journal of technical methods and pathology 78 …, 1998 | 136 | 1998 |
Protection by recombinant human interleukin-11 against experimental TNB-induced colitis in rats BS Qiu, CJ Pfeiffer, JC Keith Digestive diseases and sciences 41, 1625-1630, 1996 | 121 | 1996 |
LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse [S] EM Quinet, MD Basso, AR Halpern, DW Yates, RJ Steffan, V Clerin, ... Journal of lipid research 50 (12), 2358-2370, 2009 | 120 | 2009 |