| CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndrome PK Todd, SY Oh, A Krans, F He, C Sellier, M Frazer, AJ Renoux, K Chen, ... Neuron 78 (3), 440-455, 2013 | 507 | 2013 |
| Loss of C9 ORF 72 impairs autophagy and synergizes with polyQ Ataxin‐2 to induce motor neuron dysfunction and cell death C Sellier, ML Campanari, C Julie Corbier, A Gaucherot, I Kolb‐Cheynel, ... The EMBO journal 35 (12), 1276-1297, 2016 | 436 | 2016 |
| Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons S Almeida, E Gascon, H Tran, HJ Chou, TF Gendron, S DeGroot, ... Acta neuropathologica 126, 385-399, 2013 | 402 | 2013 |
| Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients C Sellier, F Rau, Y Liu, F Tassone, RK Hukema, R Gattoni, A Schneider, ... The EMBO journal 29 (7), 1248-1261, 2010 | 380 | 2010 |
| Sequestration of DROSHA and DGCR8 by expanded CGG RNA repeats alters microRNA processing in fragile X-associated tremor/ataxia syndrome C Sellier, F Freyermuth, R Tabet, T Tran, F He, F Ruffenach, V Alunni, ... Cell reports 3 (3), 869-880, 2013 | 252 | 2013 |
| Translation of expanded CGG repeats into FMRpolyG is pathogenic and may contribute to fragile X tremor ataxia syndrome C Sellier, RAM Buijsen, F He, S Natla, L Jung, P Tropel, A Gaucherot, ... Neuron 93 (2), 331-347, 2017 | 215 | 2017 |
| Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy F Freyermuth, F Rau, Y Kokunai, T Linke, C Sellier, M Nakamori, Y Kino, ... Nature communications 7 (1), 11067, 2016 | 180 | 2016 |
| Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers P Frick, C Sellier, IRA Mackenzie, CY Cheng, J Tahraoui-Bories, ... Acta neuropathologica communications 6, 1-17, 2018 | 125 | 2018 |
| Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders M Boivin, V Pfister, A Gaucherot, F Ruffenach, L Negroni, C Sellier, ... The EMBO journal 39 (4), e100574, 2020 | 111 | 2020 |
| A Small Molecule That Targets r(CGG)exp and Improves Defects in Fragile X-Associated Tremor Ataxia Syndrome MD Disney, B Liu, WY Yang, C Sellier, T Tran, N Charlet-Berguerand, ... ACS chemical biology 7 (10), 1711-1718, 2012 | 103 | 2012 |
| FUS-mediated regulation of acetylcholine receptor transcription at neuromuscular junctions is compromised in amyotrophic lateral sclerosis G Picchiarelli, M Demestre, A Zuko, M Been, J Higelin, S Dieterlé, MA Goy, ... Nature neuroscience 22 (11), 1793-1805, 2019 | 102 | 2019 |
| FMRpolyG-positive inclusions in CNS and non-CNS organs of a fragile X premutation carrier with fragile X-associated tremor/ataxia syndrome RAM Buijsen, C Sellier, LAWFM Severijnen, M Oulad-Abdelghani, ... Acta Neuropathologica Communications 2, 1-5, 2014 | 100 | 2014 |
| Decreased DGCR8 expression and miRNA dysregulation in individuals with 22q11. 2 deletion syndrome C Sellier, VJ Hwang, R Dandekar, B Durbin-Johnson, ... PloS one 9 (8), e103884, 2014 | 93 | 2014 |
| O-linked N-acetylglucosaminyltransferase inhibition prevents G2/M transition in Xenopus laevis oocytes V Dehennaut, T Lefebvre, C Sellier, Y Leroy, B Gross, S Walker, R Cacan, ... Journal of Biological Chemistry 282 (17), 12527-12536, 2007 | 83 | 2007 |
| Repeat-associated non-AUG (RAN) translation and other molecular mechanisms in Fragile X Tremor Ataxia Syndrome MR Glineburg, PK Todd, N Charlet-Berguerand, C Sellier Brain research 1693, 43-54, 2018 | 81 | 2018 |
| C9ORF72 is a GDP/GTP exchange factor for Rab8 and Rab39 and regulates autophagy C Corbier, C Sellier Small GTPases 8 (3), 181-186, 2017 | 74 | 2017 |
| rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences C Sellier, E Cerro-Herreros, M Blatter, F Freyermuth, A Gaucherot, ... Nature communications 9 (1), 2009, 2018 | 67 | 2018 |
| The most prevalent genetic cause of ALS-FTD, C9orf72 synergizes the toxicity of ATXN2 intermediate polyglutamine repeats through the autophagy pathway S Ciura, C Sellier, ML Campanari, N Charlet-Berguerand, E Kabashi Autophagy 12 (8), 1406-1408, 2016 | 59 | 2016 |
| The multiple molecular facets of fragile X-associated tremor/ataxia syndrome C Sellier, K Usdin, C Pastori, VJ Peschansky, F Tassone, ... Journal of neurodevelopmental disorders 6, 1-10, 2014 | 44 | 2014 |
| Potential pathogenic mechanisms underlying Fragile X Tremor Ataxia Syndrome: RAN translation and/or RNA gain-of-function? M Boivin, R Willemsen, RK Hukema, C Sellier European journal of medical genetics 61 (11), 674-679, 2018 | 34 | 2018 |
