GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses MK Lo, R Jordan, A Arvey, J Sudhamsu, P Shrivastava-Ranjan, AL Hotard, ... Scientific reports 7 (1), 43395, 2017 | 547 | 2017 |
Tryptophan-accelerated electron flow through proteins C Shih, AK Museth, M Abrahamsson, AM Blanco-Rodriguez, AJ Di Bilio, ... Science 320 (5884), 1760-1762, 2008 | 476 | 2008 |
Bacterial nitric oxide synthases BR Crane, J Sudhamsu, BA Patel Annual review of biochemistry 79 (1), 445-470, 2010 | 271 | 2010 |
Structure of the BRAF-MEK complex reveals a kinase activity independent role for BRAF in MAPK signaling JR Haling, J Sudhamsu, I Yen, S Sideris, W Sandoval, W Phung, BJ Bravo, ... Cancer cell 26 (3), 402-413, 2014 | 229 | 2014 |
Bacterial nitric oxide synthases: what are they good for? J Sudhamsu, BR Crane Trends in microbiology 17 (5), 212-218, 2009 | 171 | 2009 |
ARAF mutations confer resistance to the RAF inhibitor belvarafenib in melanoma I Yen, F Shanahan, J Lee, YS Hong, SJ Shin, AR Moore, J Sudhamsu, ... Nature 594 (7863), 418-423, 2021 | 84 | 2021 |
Negative regulation of RAF kinase activity by ATP is overcome by 14-3-3-induced dimerization NPD Liau, TJ Wendorff, JG Quinn, M Steffek, W Phung, P Liu, J Tang, ... Nature structural & molecular biology 27 (2), 134-141, 2020 | 76 | 2020 |
The structure of YqeH: an AtNOS1/AtNOA1 ortholog that couples GTP hydrolysis to molecular recognition J Sudhamsu, GI Lee, DF Klessig, BR Crane Journal of Biological Chemistry 283 (47), 32968-32976, 2008 | 69 | 2008 |
Phototriggering Electron Flow through ReI‐modified Pseudomonas aeruginosa Azurins AM Blanco‐Rodríguez, AJ Di Bilio, C Shih, AK Museth, IP Clark, M Towrie, ... Chemistry–A European Journal 17 (19), 5350-5361, 2011 | 66 | 2011 |
Co-expression of ferrochelatase allows for complete heme incorporation into recombinant proteins produced in E. coli J Sudhamsu, M Kabir, MV Airola, BA Patel, SR Yeh, DL Rousseau, ... Protein expression and purification 73 (1), 78-82, 2010 | 65 | 2010 |
EPR and ENDOR characterization of the reactive intermediates in the generation of NO by cryoreduced oxy-nitric oxide synthase from Geobacillus stearothermophilus R Davydov, J Sudhamsu, NS Lees, BR Crane, BM Hoffman Journal of the American Chemical Society 131 (40), 14493-14507, 2009 | 65 | 2009 |
Relaxation Dynamics of Pseudomonas aeruginosa ReI(CO)3(α-diimine)(HisX)+ (X = 83, 107, 109, 124, 126)CuII Azurins AM Blanco-Rodríguez, M Busby, K Ronayne, M Towrie, C Gradinaru, ... Journal of the American Chemical Society 131 (33), 11788-11800, 2009 | 59 | 2009 |
Structure and reactivity of a thermostable prokaryotic nitric-oxide synthase that forms a long-lived oxy-heme complex J Sudhamsu, BR Crane Journal of Biological Chemistry 281 (14), 9623-9632, 2006 | 57 | 2006 |
Theoretical determination of the standard reduction potential of plastocyanin in vitro SN Datta, J Sudhamsu, A Pandey The Journal of Physical Chemistry B 108 (23), 8007-8016, 2004 | 55 | 2004 |
Dimerization of LTβR by LTα1β2 is necessary and sufficient for signal transduction J Sudhamsu, JP Yin, EY Chiang, MA Starovasnik, JL Grogan, ... Proceedings of the National Academy of Sciences 110 (49), 19896-19901, 2013 | 44 | 2013 |
Structural analysis of bacterial ABC transporter inhibition by an antibody fragment S Ahuja, L Rougé, DL Swem, J Sudhamsu, P Wu, SJ Russell, ... Structure 23 (4), 713-723, 2015 | 43 | 2015 |
Azurin as a protein scaffold for a low-coordinate nonheme iron site with a small-molecule binding pocket MP McLaughlin, M Retegan, E Bill, TM Payne, HS Shafaat, S Pena, ... Journal of the American Chemical Society 134 (48), 19746-19757, 2012 | 39 | 2012 |
Dimerization induced by C-terminal 14–3–3 binding is sufficient for BRAF kinase activation NPD Liau, A Venkatanarayan, JG Quinn, W Phung, S Malek, ... Biochemistry 59 (41), 3982-3992, 2020 | 34 | 2020 |
Non-canonical reader modules of BAZ1A promote recovery from DNA damage M Oppikofer, M Sagolla, B Haley, HM Zhang, SK Kummerfeld, ... Nature Communications 8 (1), 862, 2017 | 29 | 2017 |
CRAF dimerization with ARAF regulates KRAS-driven tumor growth A Venkatanarayan, J Liang, I Yen, F Shanahan, B Haley, L Phu, ... Cell reports 38 (6), 2022 | 27 | 2022 |