A New Mechanism for β‐Lactamases: Class D Enzymes Degrade 1β‐Methyl Carbapenems via Lactone Formation CT Lohans, E van Groesen, K Kumar, CL Tooke, J Spencer, RS Paton, ... Angewandte Chemie, 2017 | 43 | 2017 |
Mechanistic insights into β-lactamase-catalysed carbapenem degradation through product characterisation CT Lohans, EI Freeman, E Groesen, CL Tooke, P Hinchliffe, J Spencer, ... Scientific reports 9 (1), 13608, 2019 | 41 | 2019 |
Recent advances in the development of semisynthetic glycopeptide antibiotics: 2014–2022 E van Groesen, P Innocenti, NI Martin ACS Infectious Diseases 8 (8), 1381-1407, 2022 | 34 | 2022 |
Non‐Hydrolytic β‐Lactam Antibiotic Fragmentation by l,d‐Transpeptidases and Serine β‐Lactamase Cysteine Variants CT Lohans, HTH Chan, TR Malla, K Kumar, JJAG Kamps, DJB McArdle, ... Angewandte Chemie International Edition 58 (7), 1990-1994, 2019 | 33 | 2019 |
Local release of siRNA using polyplex-loaded thermosensitive hydrogels LAL Fliervoet, H Zhang, E van Groesen, K Fortuin, NJCB Duin, K Remaut, ... Nanoscale 12 (18), 10347-10360, 2020 | 27 | 2020 |
Vancomyxins: Vancomycin-polymyxin nonapeptide conjugates that retain anti-Gram-positive activity with enhanced potency against Gram-negative strains E van Groesen, CJ Slingerland, P Innocenti, M Mihajlovic, R Masereeuw, ... ACS Infectious Diseases 7 (9), 2746-2754, 2021 | 22 | 2021 |
19F NMR Monitoring of Reversible Protein Post‐Translational Modifications: Class D β‐Lactamase Carbamylation and Inhibition E van Groesen, CT Lohans, J Brem, KMJ Aertker, TDW Claridge, ... Chemistry–A European Journal 25 (51), 11837-11841, 2019 | 20 | 2019 |
Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity E van Groesen, E Mons, I Kotsogianni, M Arts, KHME Tehrani, N Wade, ... Science Translational Medicine 16 (759), eabo4736, 2024 | | 2024 |
Specific Targeting and Killing of Antibiotic-Resistant Bacteria by Phototoxic Flavin-conjugated Compounds Y Xu, E van Groesen, R Cox, JH Lorent, R van Beekveld, ... The Bacterial Cell Envelope: Specific Labeling and Its Applications, 155, 2024 | | 2024 |
Antibiotic Compounds NI Martin, E Van Groesen, KHME Tehrani, N Wade US Patent App. 17/761,376, 2023 | | 2023 |