From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance T Litman, TE Druley, WD Stein, SE Bates Cellular and Molecular Life Sciences CMLS 58, 931-959, 2001 | 920 | 2001 |
Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia TN Wong, G Ramsingh, AL Young, CA Miller, W Touma, JS Welch, ... Nature 518 (7540), 552-555, 2015 | 825 | 2015 |
Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults AL Young, GA Challen, BM Birmann, TE Druley Nature communications 7 (1), 12484, 2016 | 657 | 2016 |
Cancer therapy shapes the fitness landscape of clonal hematopoiesis KL Bolton, RN Ptashkin, T Gao, L Braunstein, SM Devlin, D Kelly, M Patel, ... Nature genetics 52 (11), 1219-1226, 2020 | 452 | 2020 |
The evolutionary dynamics and fitness landscape of clonal hematopoiesis CJ Watson, AL Papula, GYP Poon, WH Wong, AL Young, TE Druley, ... Science 367 (6485), 1449-1454, 2020 | 342 | 2020 |
Integrated analysis of germline and somatic variants in ovarian cancer KL Kanchi, KJ Johnson, C Lu, MD McLellan, MDM Leiserson, MC Wendl, ... Nature communications 5 (1), 3156, 2014 | 316 | 2014 |
Whole-exome capture and sequencing identifies HEATR2 mutation as a cause of primary ciliary dyskinesia A Horani, TE Druley, MA Zariwala, AC Patel, BT Levinson, ... The American Journal of Human Genetics 91 (4), 685-693, 2012 | 245 | 2012 |
P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity EB Mechetner, B Schott, BS Morse, WD Stein, T Druley, KA Davis, ... Proceedings of the National Academy of Sciences 94 (24), 12908-12913, 1997 | 237 | 1997 |
Quantification of rare allelic variants from pooled genomic DNA TE Druley, FLM Vallania, DJ Wegner, KE Varley, OL Knowles, JA Bonds, ... Nature methods 6 (4), 263-265, 2009 | 224 | 2009 |
Surveillance recommendations for children with overgrowth syndromes and predisposition to Wilms tumors and hepatoblastoma JM Kalish, L Doros, LJ Helman, RC Hennekam, RP Kuiper, SM Maas, ... Clinical Cancer Research 23 (13), e115-e122, 2017 | 184 | 2017 |
Recommendations for surveillance for children with leukemia-predisposing conditions CC Porter, TE Druley, A Erez, RP Kuiper, K Onel, JD Schiffman, ... Clinical Cancer Research 23 (11), e14-e22, 2017 | 117 | 2017 |
Single ABCA3 Mutations Increase Risk for Neonatal Respiratory Distress Syndrome JA Wambach, DJ Wegner, K DePass, H Heins, TE Druley, RD Mitra, P An, ... Pediatrics 130 (6), e1575-e1582, 2012 | 117 | 2012 |
Myosin binding protein C1: a novel gene for autosomal dominant distal arthrogryposis type 1 CA Gurnett, DM Desruisseau, K McCall, R Choi, ZI Meyer, M Talerico, ... Human molecular genetics 19 (7), 1165-1173, 2010 | 108 | 2010 |
Traditional and targeted exome sequencing reveals common, rare and novel functional deleterious variants in RET-signaling complex in a cohort of living US patients with urinary … R Chatterjee, E Ramos, M Hoffman, J VanWinkle, DR Martin, TK Davis, ... Human genetics 131, 1725-1738, 2012 | 99 | 2012 |
Clonal hematopoiesis and risk of acute myeloid leukemia AL Young, RS Tong, BM Birmann, TE Druley haematologica 104 (12), 2410, 2019 | 96 | 2019 |
Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease SJ Matkovich, DJ Van Booven, A Hindes, MY Kang, TE Druley, ... The Journal of clinical investigation 120 (1), 280-289, 2010 | 91 | 2010 |
Quantifying ultra-rare pre-leukemic clones via targeted error-corrected sequencing AL Young, TN Wong, AEO Hughes, SE Heath, TJ Ley, DC Link, TE Druley Leukemia 29 (7), 1608-1611, 2015 | 90 | 2015 |
High-throughput discovery of rare insertions and deletions in large cohorts FLM Vallania, TE Druley, E Ramos, J Wang, I Borecki, M Province, ... Genome research 20 (12), 1711-1718, 2010 | 81 | 2010 |
Genome wide association and linkage analyses identified three loci—4q25, 17q23. 2, and 10q11. 21—associated with variation in leukocyte telomere length: the Long Life Family … JH Lee, R Cheng, LS Honig, M Feitosa, CM Kammerer, MS Kang, ... Frontiers in genetics 4, 310, 2014 | 80 | 2014 |
Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence G Haller, T Druley, FL Vallania, RD Mitra, P Li, G Akk, JH Steinbach, ... Human molecular genetics 21 (3), 647-655, 2012 | 77 | 2012 |