YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase PA Scotti, ML Urbanus, J Brunner, JWL de Gier, G von Heijne, ... The EMBO journal 19 (4), 542-549, 2000 | 509 | 2000 |
Mapping the cellular response to small molecules using chemogenomic fitness signatures AY Lee, RP St. Onge, MJ Proctor, IM Wallace, AH Nile, PA Spagnuolo, ... Science 344 (6180), 208-211, 2014 | 266 | 2014 |
Sec-dependent membrane protein insertion: sequential interaction of nascent FtsQ with SecY and YidC ML Urbanus, PA Scotti, L Fröderberg, A Sääf, JWL de Gier, J Brunner, ... EMBO reports 2 (6), 524-529, 2001 | 239 | 2001 |
A conserved function of YidC in the biogenesis of respiratory chain complexes M van der Laan, ML Urbanus, CM Ten Hagen-Jongman, N Nouwen, ... Proceedings of the National Academy of Sciences 100 (10), 5801-5806, 2003 | 189 | 2003 |
Genome-wide analysis of intracellular pH reveals quantitative control of cell division rate by pHc in Saccharomyces cerevisiae. R Orij, ML Urbanus, FJ Vizeacoumar, G Giaever, C Boone, C Nislow, ... Genome Biology 13 (R80), 2012 | 171 | 2012 |
Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors MA Sukhai, S Prabha, R Hurren, AC Rutledge, AY Lee, ... The Journal of clinical investigation 123 (1), 2012 | 159 | 2012 |
Signal recognition particle (SRP)-mediated targeting and Sec-dependent translocation of an extracellular Escherichia coli protein R Sijbrandi, ML Urbanus, M Corinne, HD Bernstein, B Oudega, BR Otto, ... Journal of Biological Chemistry 278 (7), 4654-4659, 2003 | 155 | 2003 |
Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila ML Urbanus, AT Quaile, PJ Stogios, M Morar, C Rao, R Di Leo, ... Molecular systems biology 12 (12), 893, 2016 | 129 | 2016 |
Targeting, insertion, and localization of Escherichia coli YidC ML Urbanus, L Fröderberg, D Drew, P Björk, JWL de Gier, J Brunner, ... Journal of Biological Chemistry 277 (15), 12718-12723, 2002 | 122 | 2002 |
SecA is not required for signal recognition particle-mediated targeting and initial membrane insertion of a nascent inner membrane protein PA Scotti, QA Valent, EH Manting, ML Urbanus, AJM Driessen, B Oudega, ... Journal of Biological Chemistry 274 (42), 29883-29888, 1999 | 112 | 1999 |
Detection of cross-links between FtsH, YidC, HflK/C suggests a linked role for these proteins in quality control upon insertion of bacterial inner membrane proteins E van Bloois, HL Dekker, L Fröderberg, ENG Houben, ML Urbanus, ... FEBS letters 582 (10), 1419-1424, 2008 | 97 | 2008 |
Mixed-disulfide folding intermediates between thyroglobulin and endoplasmic reticulum resident oxidoreductases ERp57 and protein disulfide isomerase B Di Jeso, Y Park, L Ulianich, AS Treglia, ML Urbanas, S High, P Arvan Molecular and cellular biology 25 (22), 9793-9805, 2005 | 96 | 2005 |
YidC and SecY mediate membrane insertion of a Type I transmembrane domain ENG Houben, ML Urbanus, M Van Der Laan, CM ten Hagen-Jongman, ... Journal of Biological Chemistry 277 (39), 35880-35886, 2002 | 72 | 2002 |
Decreasing the chlorophyll a/b ratio in reconstituted LHCII: structural and functional consequences FJ Kleima, S Hobe, F Calkoen, ML Urbanus, EJG Peterman, ... Biochemistry 38 (20), 6587-6596, 1999 | 68 | 1999 |
Compound prioritization methods increase rates of chemical probe discovery in model organisms IM Wallace, ML Urbanus, GM Luciani, AR Burns, MKL Han, H Wang, ... Chemistry & biology 18 (10), 1273-1283, 2011 | 56 | 2011 |
Molecular characterization of LubX: functional divergence of the U-box fold by Legionella pneumophila AT Quaile, ML Urbanus, PJ Stogios, B Nocek, T Skarina, AW Ensminger, ... Structure 23 (8), 1459-1469, 2015 | 54 | 2015 |
Discovery of ubiquitin deamidases in the pathogenic arsenal of Legionella pneumophila D Valleau, AT Quaile, H Cui, X Xu, E Evdokimova, C Chang, ME Cuff, ... Cell reports 23 (2), 568-583, 2018 | 49 | 2018 |
Competitive genomic screens of barcoded yeast libraries AM Smith, T Durbic, J Oh, M Urbanus, M Proctor, LE Heisler, G Giaever, ... JoVE (Journal of Visualized Experiments), e2864, 2011 | 47 | 2011 |
The automated cell: compound and environment screening system (ACCESS) for chemogenomic screening M Proctor, ML Urbanus, EL Fung, DF Jaramillo, RW Davis, C Nislow, ... Yeast Systems Biology: Methods and Protocols, 239-269, 2011 | 36 | 2011 |
Dafadine inhibits DAF-9 to promote dauer formation and longevity of Caenorhabditis elegans GM Luciani, L Magomedova, R Puckrin, ML Urbanus, IM Wallace, ... Nature chemical biology 7 (12), 891-893, 2011 | 34 | 2011 |