Mouse models of diet-induced nonalcoholic steatohepatitis reproduce the heterogeneity of the human disease MV Machado, GA Michelotti, G Xie, TP de Almeida, J Boursier, B Bohnic, ... PloS one 10 (5), e0127991, 2015 | 397 | 2015 |
Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease WK Syn, Y Htun Oo, TA Pereira, GF Karaca, Y Jung, A Omenetti, RP Witek, ... Hepatology 51 (6), 1998-2007, 2010 | 298 | 2010 |
Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis WK Syn, SS Choi, E Liaskou, GF Karaca, KM Agboola, YH Oo, Z Mi, ... Hepatology 53 (1), 106-115, 2011 | 290 | 2011 |
NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease WK Syn, KM Agboola, M Swiderska, GA Michelotti, E Liaskou, H Pang, ... Gut 61 (9), 1323-1329, 2012 | 288 | 2012 |
Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease WK Syn, Y Jung, A Omenetti, M Abdelmalek, CD Guy, L Yang, J Wang, ... Gastroenterology 137 (4), 1478-1488. e8, 2009 | 287 | 2009 |
Pan‐caspase inhibitor VX‐166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis RP Witek, WC Stone, FG Karaca, WK Syn, TA Pereira, KM Agboola, ... Hepatology 50 (5), 1421-1430, 2009 | 284 | 2009 |
Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma T de Almeida Pereira, RP Witek, WK Syn, SS Choi, S Bradrick, GF Karaca, ... Laboratory investigation 90 (12), 1690-1703, 2010 | 138 | 2010 |
Accumulation of duct cells with activated YAP parallels fibrosis progression in non-alcoholic fatty liver disease MV Machado, GA Michelotti, TA Pereira, G Xie, R Premont, H Cortez-Pinto, ... Journal of hepatology 63 (4), 962-970, 2015 | 121 | 2015 |
Reduced lipoapoptosis, hedgehog pathway activation and fibrosis in caspase-2 deficient mice with non-alcoholic steatohepatitis MV Machado, GA Michelotti, T de Almeida Pereira, J Boursier, L Kruger, ... Gut 64 (7), 1148-1157, 2015 | 103 | 2015 |
Macrophage‐derived hedgehog ligands promotes fibrogenic and angiogenic responses in human schistosomiasis mansoni TA Pereira, G Xie, SS Choi, WK Syn, I Voieta, J Lu, IS Chan, M Swiderska, ... Liver International 33 (1), 149-161, 2013 | 76 | 2013 |
Repair-related activation of hedgehog signaling in stromal cells promotes intrahepatic hypothyroidism BN Bohinc, G Michelotti, G Xie, H Pang, A Suzuki, CD Guy, D Piercy, ... Endocrinology 155 (11), 4591-4601, 2014 | 68 | 2014 |
Activation of Rac1 promotes hedgehog‐mediated acquisition of the myofibroblastic phenotype in rat and human hepatic stellate cells SS Choi, RP Witek, L Yang, A Omenetti, WK Syn, CA Moylan, Y Jung, ... Hepatology 52 (1), 278-290, 2010 | 61 | 2010 |
Paracrine Hedgehog signaling drives metabolic changes in hepatocellular carcinoma IS Chan, CD Guy, Y Chen, J Lu, M Swiderska-Syn, GA Michelotti, ... Cancer research 72 (24), 6344-6350, 2012 | 55 | 2012 |
Caspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease MV Machado, GA Michelotti, ML Jewell, TA Pereira, G Xie, RT Premont, ... Cell death & disease 7 (2), e2096-e2096, 2016 | 53 | 2016 |
Sensitivity and specificity of the circulating cathodic antigen rapid urine test in the diagnosis of Schistosomiasis mansoni infection and evaluation of morbidity in a … FT Ferreira, TA Fidelis, TA Pereira, A Otoni, LC Queiroz, FF Amâncio, ... Revista da Sociedade Brasileira de Medicina Tropical 50 (03), 358-364, 2017 | 44 | 2017 |
Anti-IL-13Rα2 therapy promotes recovery in a murine model of inflammatory bowel disease EP Karmele, TS Pasricha, TR Ramalingam, RW Thompson, RL Gieseck III, ... Mucosal immunology 12 (5), 1174-1186, 2019 | 41 | 2019 |
Genetic differences in oxidative stress and inflammatory responses to diet‐induced obesity do not alter liver fibrosis in mice WK Syn, L Yang, DJ Chiang, Y Qian, Y Jung, G Karaca, SS Choi, ... Liver International 29 (8), 1262-1272, 2009 | 38 | 2009 |
Emerging role of HMGB1 in the pathogenesis of schistosomiasis liver fibrosis ARR Vicentino, VC Carneiro, D Allonso, RF Guilherme, CF Benjamim, ... Frontiers in immunology 9, 1979, 2018 | 36 | 2018 |
MCM3: a novel proliferation marker in oral squamous cell carcinoma LF Valverde, RD de Freitas, TA Pereira, MF de Resende, IMG Agra, ... Applied Immunohistochemistry & Molecular Morphology 26 (2), 120-125, 2018 | 36 | 2018 |
Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni TA Pereira, WK Syn, MV Machado, PV Vidigal, V Resende, I Voieta, G Xie, ... Clinical science 129 (10), 875-883, 2015 | 36 | 2015 |