| Discovery of novel alkylated (bis) urea and (bis) thiourea polyamine analogues with potent antimalarial activities BK Verlinden, J Niemand, J Snyman, SK Sharma, RJ Beattie, PM Woster, ... Journal of medicinal chemistry 54 (19), 6624-6633, 2011 | 123 | 2011 |
| Polyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilities LM Birkholtz, M Williams, J Niemand, AI Louw, L Persson, O Heby Biochemical Journal 438 (2), 229-244, 2011 | 115 | 2011 |
| Hierarchical transcriptional control regulates Plasmodium falciparum sexual differentiation R Van Biljon, R Van Wyk, HJ Painter, L Orchard, J Reader, J Niemand, ... BMC genomics 20, 1-16, 2019 | 83 | 2019 |
| Bioassay-guided isolation and identification of gametocytocidal compounds from Artemisia afra (Asteraceae) P Moyo, P Kunyane, MA Selepe, JN Eloff, J Niemand, AI Louw, ... Malaria journal 18, 1-11, 2019 | 46 | 2019 |
| Functional consequences of perturbing polyamine metabolism in the malaria parasite, Plasmodium falciparum K Clark, J Niemand, S Reeksting, S Smit, AC Van Brummelen, M Williams, ... Amino Acids 38, 633-644, 2010 | 46 | 2010 |
| Inducing controlled cell cycle arrest and re-entry during asexual proliferation of Plasmodium falciparum malaria parasites R van Biljon, J Niemand, R van Wyk, K Clark, B Verlinden, C Abrie, ... Scientific reports 8 (1), 16581, 2018 | 43 | 2018 |
| In vitro inhibition of Plasmodium falciparum early and late stage gametocyte viability by extracts from eight traditionally used South African plant species P Moyo, ME Botha, S Nondaba, J Niemand, VJ Maharaj, JN Eloff, AI Louw, ... Journal of ethnopharmacology 185, 235-242, 2016 | 40 | 2016 |
| Exploring functional genomics for drug target and therapeutics discovery in Plasmodia L Birkholtz, AC Van Brummelen, K Clark, J Niemand, E Maréchal, ... Acta tropica 105 (2), 113-123, 2008 | 35 | 2008 |
| Polyamine uptake by the intraerythrocytic malaria parasite, Plasmodium falciparum J Niemand, AI Louw, L Birkholtz, K Kirk International journal for parasitology 42 (10), 921-929, 2012 | 30 | 2012 |
| Interrogating alkyl and arylalkylpolyamino (bis) urea and (bis) thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum … BK Verlinden, M De Beer, B Pachaiyappan, E Besaans, WA Andayi, ... Bioorganic & medicinal chemistry 23 (16), 5131-5143, 2015 | 28 | 2015 |
| Potent Plasmodium falciparum gametocytocidal compounds identified by exploring the kinase inhibitor chemical space for dual active antimalarials ME van der Watt, J Reader, A Churchyard, SH Nondaba, SB Lauterbach, ... Journal of antimicrobial chemotherapy 73 (5), 1279-1290, 2018 | 25 | 2018 |
| Morphological and Molecular Descriptors of the Developmental Cycle of Babesia divergens Parasites in Human Erythrocytes I Rossouw, C Maritz-Olivier, J Niemand, R van Biljon, A Smit, NA Olivier, ... PLoS neglected tropical diseases 9 (5), e0003711, 2015 | 24 | 2015 |
| Human Aurora kinase inhibitor Hesperadin reveals epistatic interaction between Plasmodium falciparum PfArk1 and PfNek1 kinases BJ Morahan, C Abrie, K Al-Hasani, MB Batty, V Corey, AN Cowell, ... Communications biology 3 (1), 701, 2020 | 23 | 2020 |
| Anthracene-Polyamine Conjugates Inhibit In Vitro Proliferation of Intraerythrocytic Plasmodium falciparum Parasites J Niemand, P Burger, BK Verlinden, J Reader, AM Joubert, A Kaiser, ... Antimicrobial agents and chemotherapy 57 (6), 2874-2877, 2013 | 22 | 2013 |
| Understanding human genetic factors influencing primaquine safety and efficacy to guide primaquine roll-out in a pre-elimination setting in southern Africa SS Awandu, J Raman, TI Makhanthisa, P Kruger, J Frean, T Bousema, ... Malaria Journal 17, 1-11, 2018 | 14 | 2018 |
| Novel S-adenosyl-L-methionine decarboxylase inhibitors as potent antiproliferative agents against intraerythrocytic Plasmodium falciparum parasites D Le Roux, PB Burger, J Niemand, A Grobler, P Urbán, ... International Journal for Parasitology: Drugs and Drug Resistance 4 (1), 28-36, 2014 | 9 | 2014 |
| Biochemical characterisation of putrescine and spermidine uptake as a potential therapeutic target against the human malaria parasite, Plasmodium falciparum J Niemand University of Pretoria, 2012 | 4 | 2012 |
| Genetic complexity alters drug susceptibility of asexual and gametocyte stages of Plasmodium falciparum to antimalarial candidates N Greyling, M van der Watt, H Gwarinda, A van Heerden, B Greenhouse, ... Antimicrobial Agents and Chemotherapy 68 (3), e01291-23, 2024 | 2 | 2024 |
| Chemogenomic fingerprints associated with stage-specific gametocytocidal compound action against human malaria parasites J Niemand, R Van Biljon, M Van Der Watt, A Van Heerden, J Reader, ... ACS Infectious Diseases 7 (10), 2904-2916, 2021 | 2 | 2021 |
| Polyamine uptake in the malaria parasite, Plasmodium falciparum, is dependent on the parasite's membrane potential J Niemand, L Birkholtz, AI Louw, K Kirk Malaria Journal 9, 1-1, 2010 | 2 | 2010 |
