Comparative tumor RNA sequencing analysis for difficult-to-treat pediatric and young adult patients with cancer OM Vaske, I Bjork, SR Salama, H Beale, AT Shah, L Sanders, J Pfeil, ... JAMA network open 2 (10), e1913968-e1913968, 2019 | 48 | 2019 |
Barriers to accessing public cancer genomic data K Learned, A Durbin, R Currie, ET Kephart, HC Beale, LM Sanders, J Pfeil, ... Scientific data 6 (1), 1-7, 2019 | 39 | 2019 |
Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome BJ Golbourn, ME Halbert, K Halligan, S Varadharajan, B Krug, NE Mbah, ... Nature Cancer 3 (5), 629-648, 2022 | 28 | 2022 |
The scalable precision medicine open knowledge engine (SPOKE): a massive knowledge graph of biomedical information JH Morris, K Soman, RE Akbas, X Zhou, B Smith, EC Meng, CC Huang, ... Bioinformatics 39 (2), btad080, 2023 | 27 | 2023 |
Identification of Novel RAS Signaling Therapeutic Vulnerabilities in Diffuse Intrinsic Pontine GliomasRAS Pathway Vulnerabilities in Histone-Mutant DIPG RF Koncar, BR Dey, ACJ Stanton, N Agrawal, ML Wassell, LH McCarl, ... Cancer Research 79 (16), 4026-4041, 2019 | 24 | 2019 |
Biomonitoring and precision health in deep space supported by artificial intelligence RT Scott, LM Sanders, EL Antonsen, JJA Hastings, S Park, G Mackintosh, ... Nature Machine Intelligence 5 (3), 196-207, 2023 | 17 | 2023 |
Identification of a differentiation stall in epithelial mesenchymal transition in histone H3–mutant diffuse midline glioma LM Sanders, A Cheney, L Seninge, A van den Bout, M Chen, HC Beale, ... GigaScience 9 (12), giaa136, 2020 | 15 | 2020 |
Biological research and self-driving labs in deep space supported by artificial intelligence LM Sanders, RT Scott, JH Yang, AA Qutub, H Garcia Martin, DC Berrios, ... Nature Machine Intelligence 5 (3), 208-219, 2023 | 14 | 2023 |
Validating Causal Diagrams of Human Health Risks for Spaceflight: An Example Using Bone Data from Rodents RJ Reynolds, RT Scott, RT Turner, UT Iwaniec, ML Bouxsein, LM Sanders, ... Biomedicines 10 (9), 2187, 2022 | 12 | 2022 |
Cancer microenvironment and genomics: evolution in process SP Leong, IP Witz, O Sagi-Assif, S Izraely, J Sleeman, B Piening, BA Fox, ... Clinical & Experimental Metastasis, 1-15, 2021 | 10 | 2021 |
A Second Space Age Spanning Omics, Platforms, and Medicine Across Orbits CE Mason, J Green, KI Adamopoulos, EE Afshin, JJ Baechle, M Basner, ... Nature, 1-4, 2024 | 6 | 2024 |
Beyond Low Earth Orbit: Biomonitoring, Artificial Intelligence, and Precision Space Health RT Scott, EL Antonsen, LM Sanders, JJA Hastings, S Park, G Mackintosh, ... arXiv preprint arXiv:2112.12554, 2021 | 5 | 2021 |
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank EG Overbey, JK Kim, BT Tierney, J Park, N Houerbi, AG Lucaci, ... Nature, 1-3, 2024 | 4 | 2024 |
Batch effect correction methods for NASA GeneLab transcriptomic datasets LM Sanders, H Chok, F Samson, AU Acuna, SHL Polo, V Boyko, YC Chen, ... Frontiers in Astronomy and Space Sciences 10, 1200132, 2023 | 4 | 2023 |
Machine learning multi-omics analysis reveals cancer driver dysregulation in pan-cancer cell lines compared to primary tumors LM Sanders, R Chandra, N Zebarjadi, HC Beale, AG Lyle, A Rodriguez, ... Communications Biology 5 (1), 1367, 2022 | 4 | 2022 |
Hydra: A mixture modeling framework for subtyping pediatric cancer cohorts using multimodal gene expression signatures J Pfeil, LM Sanders, I Anastopoulos, AG Lyle, AS Weinstein, Y Xue, ... PLoS computational biology 16 (4), e1007753, 2020 | 4 | 2020 |
Comparative RNA-seq analysis aids in diagnosis of a rare pediatric tumor LM Sanders, A Rangaswami, I Bjork, HC Beale, ET Kephart, A Durbin, ... Molecular Case Studies 5 (5), a004317, 2019 | 4 | 2019 |
Invariant risk minimisation for cross-organism inference: substituting mouse data for human data in human risk factor discovery O O'Donoghue, P Duckworth, G Ughi, L Scheibenreif, K Khezeli, ... arXiv preprint arXiv:2111.07348, 2021 | 3 | 2021 |
Explainable machine learning identifies multi-omics signatures of muscle response to spaceflight in mice K Li, R Desai, RT Scott, JR Steele, M Machado, S Demharter, A Hoarfrost, ... npj Microgravity 9 (1), 90, 2023 | 2 | 2023 |
Author Correction: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome BJ Golbourn, ME Halbert, K Halligan, S Varadharajan, B Krug, NE Mbah, ... Nature Cancer 3 (7), 899-899, 2022 | 2 | 2022 |